(data stored in ACNUC7421 zone)

SWISSPROT: A0A0H2ZKK4_PSEAB

ID   A0A0H2ZKK4_PSEAB        Unreviewed;       369 AA.
AC   A0A0H2ZKK4;
DT   16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT   16-SEP-2015, sequence version 1.
DT   08-MAY-2019, entry version 25.
DE   RecName: Full=Spermidine/putrescine import ATP-binding protein PotA {ECO:0000256|RuleBase:RU364083};
DE            EC=7.6.2.11 {ECO:0000256|RuleBase:RU364083};
GN   Name=potA {ECO:0000256|RuleBase:RU364083};
GN   OrderedLocusNames=PA14_07860 {ECO:0000313|EMBL:ABJ15567.1};
OS   Pseudomonas aeruginosa (strain UCBPP-PA14).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=208963 {ECO:0000313|EMBL:ABJ15567.1, ECO:0000313|Proteomes:UP000000653};
RN   [1] {ECO:0000313|EMBL:ABJ15567.1, ECO:0000313|Proteomes:UP000000653}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UCBPP-PA14 {ECO:0000313|EMBL:ABJ15567.1,
RC   ECO:0000313|Proteomes:UP000000653};
RX   PubMed=17038190; DOI=10.1186/gb-2006-7-10-r90;
RA   Lee D.G., Urbach J.M., Wu G., Liberati N.T., Feinbaum R.L., Miyata S.,
RA   Diggins L.T., He J., Saucier M., Deziel E., Friedman L., Li L.,
RA   Grills G., Montgomery K., Kucherlapati R., Rahme L.G., Ausubel F.M.;
RT   "Genomic analysis reveals that Pseudomonas aeruginosa virulence is
RT   combinatorial.";
RL   Genome Biol. 7:R90.1-R90.14(2006).
CC   -!- FUNCTION: Part of the ABC transporter complex PotABCD involved in
CC       spermidine/putrescine import. Responsible for energy coupling to
CC       the transport system. {ECO:0000256|RuleBase:RU364083,
CC       ECO:0000256|SAAS:SAAS00083152}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H(2)O + polyamine-[polyamine-binding protein](Side
CC         1) = ADP + phosphate + polyamine(Side 2) + [polyamine-binding
CC         protein](Side 1).; EC=7.6.2.11;
CC         Evidence={ECO:0000256|RuleBase:RU364083,
CC         ECO:0000256|SAAS:SAAS01153263};
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins
CC       (PotA), two transmembrane proteins (PotB and PotC) and a solute-
CC       binding protein (PotD). {ECO:0000256|RuleBase:RU364083,
CC       ECO:0000256|SAAS:SAAS00083151}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily.
CC       Spermidine/putrescine importer (TC 3.A.1.11.1) family.
CC       {ECO:0000256|RuleBase:RU364083, ECO:0000256|SAAS:SAAS00569590}.
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DR   EMBL; CP000438; ABJ15567.1; -; Genomic_DNA.
DR   RefSeq; WP_003085109.1; NC_008463.1.
DR   SMR; A0A0H2ZKK4; -.
DR   EnsemblBacteria; ABJ15567; ABJ15567; PA14_07860.
DR   KEGG; pau:PA14_07860; -.
DR   KO; K02052; -.
DR   OMA; QQIAPPR; -.
DR   BioCyc; PAER208963:G1G74-648-MONOMER; -.
DR   Proteomes; UP000000653; Chromosome.
DR   GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0015417; F:polyamine-transporting ATPase activity; IEA:InterPro.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like.
DR   InterPro; IPR017871; ABC_transporter_CS.
DR   InterPro; IPR008995; Mo/tungstate-bd_C_term_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005893; Sp_pt_ABC_ATP-bd.
DR   InterPro; IPR013611; Transp-assoc_OB_typ2.
DR   Pfam; PF00005; ABC_tran; 1.
DR   Pfam; PF08402; TOBE_2; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF50331; SSF50331; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR01187; potA; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE   3: Inferred from homology;
DR   PRODOM; A0A0H2ZKK4.
DR   SWISS-2DPAGE; A0A0H2ZKK4.
KW   ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00434,
KW   ECO:0000256|RuleBase:RU364083, ECO:0000256|SAAS:SAAS00237035,
KW   ECO:0000313|EMBL:ABJ15567.1};
KW   Cell membrane {ECO:0000256|RuleBase:RU364083,
KW   ECO:0000256|SAAS:SAAS00458580};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000653};
KW   Membrane {ECO:0000256|RuleBase:RU364083,
KW   ECO:0000256|SAAS:SAAS00458555};
KW   Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00434,
KW   ECO:0000256|RuleBase:RU364083, ECO:0000256|SAAS:SAAS00452314};
KW   Translocase {ECO:0000256|RuleBase:RU364083,
KW   ECO:0000256|SAAS:SAAS01153264};
KW   Transport {ECO:0000256|RuleBase:RU364083,
KW   ECO:0000256|SAAS:SAAS00237071}.
FT   DOMAIN       11    242       ABC transporter. {ECO:0000259|PROSITE:
FT                                PS50893}.
FT   NP_BIND      44     51       ATP. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00434}.
SQ   SEQUENCE   369 AA;  40656 MW;  404060ED351FAB50 CRC64;
     MAETQGGDVL VSFRGVQKSY DGETLIVKDL NLDIRKGEFL TLLGPSGSGK TTSLMMLAGF
     ETPTAGEILL AGRSINNVPP HKRDIGMVFQ NYALFPHMTV AENLAFPLSV RGMSKTDVKE
     RVKRALSMVQ LDAFAGRYPA QLSGGQQQRV ALARALVFEP QLVLMDEPLG ALDKQLREHM
     QMEIKHLHQR LGVTVVYVTH DQGEALTMSD RVAVFHQGEI QQIEPPRNLY EQPRNTFVAN
     FIGENNRLSG QLLSCDGERC VVGLPRGEKV EALAVNVGQP GEPVTLSIRP ERVRLNGASE
     SCVNRFSGRV AEFVYLGDHV RVRLEVCGRD DFFVKQPIAE LDPTLSVGDV VPLGWQVEHV
     RALDPLPAA
//

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