(data stored in ACNUC7421 zone)

SWISSPROT: CH601_SYNFM

ID   CH601_SYNFM             Reviewed;         543 AA.
AC   A0LEH2;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   12-DEC-2006, sequence version 1.
DT   11-DEC-2019, entry version 81.
DE   RecName: Full=60 kDa chaperonin 1 {ECO:0000255|HAMAP-Rule:MF_00600};
DE   AltName: Full=GroEL protein 1 {ECO:0000255|HAMAP-Rule:MF_00600};
DE   AltName: Full=Protein Cpn60 1 {ECO:0000255|HAMAP-Rule:MF_00600};
GN   Name=groL1 {ECO:0000255|HAMAP-Rule:MF_00600};
GN   Synonyms=groEL1 {ECO:0000255|HAMAP-Rule:MF_00600};
GN   OrderedLocusNames=Sfum_0121;
OS   Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Syntrophobacterales;
OC   Syntrophobacteraceae; Syntrophobacter.
OX   NCBI_TaxID=335543;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 10017 / MPOB;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Pitluck S., Goltsman E.G.,
RA   Martinez M., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Kim E., Boone D.R., Brockman F., Culley D., Ferry J., Gunsalus R.,
RA   McInerney M.J., Morrison M., Plugge C., Rohlin L., Scholten J., Sieber J.,
RA   Stams A.J.M., Worm P., Henstra A.M., Richardson P.;
RT   "Complete sequence of Syntrophobacter fumaroxidans MPOB.";
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Prevents misfolding and promotes the refolding and proper
CC       assembly of unfolded polypeptides generated under stress conditions.
CC       {ECO:0000255|HAMAP-Rule:MF_00600}.
CC   -!- SUBUNIT: Oligomer of 14 subunits composed of two stacked rings of 7
CC       subunits. {ECO:0000255|HAMAP-Rule:MF_00600}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00600}.
CC   -!- SIMILARITY: Belongs to the chaperonin (HSP60) family.
CC       {ECO:0000255|HAMAP-Rule:MF_00600}.
DR   EMBL; CP000478; ABK15824.1; -; Genomic_DNA.
DR   RefSeq; WP_011696997.1; NC_008554.1.
DR   SMR; A0LEH2; -.
DR   STRING; 335543.Sfum_0121; -.
DR   PRIDE; A0LEH2; -.
DR   EnsemblBacteria; ABK15824; ABK15824; Sfum_0121.
DR   KEGG; sfu:Sfum_0121; -.
DR   eggNOG; ENOG4105CJ9; Bacteria.
DR   eggNOG; COG0459; LUCA.
DR   HOGENOM; HOG000076290; -.
DR   KO; K04077; -.
DR   OMA; GEQRLWA; -.
DR   OrthoDB; 265347at2; -.
DR   BioCyc; SFUM335543:G1G7I-127-MONOMER; -.
DR   Proteomes; UP000001784; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0042026; P:protein refolding; IEA:UniProtKB-UniRule.
DR   CDD; cd03344; GroEL; 1.
DR   Gene3D; 1.10.560.10; -; 1.
DR   Gene3D; 3.30.260.10; -; 1.
DR   Gene3D; 3.50.7.10; -; 1.
DR   HAMAP; MF_00600; CH60; 1.
DR   InterPro; IPR018370; Chaperonin_Cpn60_CS.
DR   InterPro; IPR001844; Chaprnin_Cpn60.
DR   InterPro; IPR002423; Cpn60/TCP-1.
DR   InterPro; IPR027409; GroEL-like_apical_dom_sf.
DR   InterPro; IPR027413; GROEL-like_equatorial_sf.
DR   InterPro; IPR027410; TCP-1-like_intermed_sf.
DR   Pfam; PF00118; Cpn60_TCP1; 1.
DR   PRINTS; PR00298; CHAPERONIN60.
DR   SUPFAM; SSF48592; SSF48592; 1.
DR   SUPFAM; SSF52029; SSF52029; 1.
DR   SUPFAM; SSF54849; SSF54849; 1.
DR   TIGRFAMs; TIGR02348; GroEL; 1.
DR   PROSITE; PS00296; CHAPERONINS_CPN60; 1.
PE   3: Inferred from homology;
DR   PRODOM; A0LEH2.
DR   SWISS-2DPAGE; A0LEH2.
KW   ATP-binding; Chaperone; Cytoplasm; Nucleotide-binding; Reference proteome.
FT   CHAIN           1..543
FT                   /note="60 kDa chaperonin 1"
FT                   /id="PRO_0000332094"
SQ   SEQUENCE   543 AA;  57766 MW;  4BED24F2400B32A3 CRC64;
     MAKQLIYDVK AREALLSGVN ILADAVKVTL GPKGRNVVIE KAFGGPTVTK DGVTVAKEIE
     LEDKFENMGA QMVKEVASKT SDVAGDGTTT ATILAQSIYY EGSKLVAAGA NPMALKRGIE
     KAVQVVVDEL KKISKPTKDQ KEIAQVGTIS ANNDPTIGNI IAEAMNKVGK EGVITVEEAK
     AMETTLEVVE GMQFDRGYIS PYFVTDPEKM EVLLNEPLIL INEKKISNMK DLLPVLEQIA
     KMGRPLLIIA EDVEGEALAT LVVNKLRGTL HVCAVKAPGF GDRRKAMLDD IAILTGGQVI
     SEEKGIKLES VGLNDLGKAK TIRIDKDNTT IVDGAGDRKA LEGRVRQIRT QIDETTSDYD
     REKLQERLAK MVGGVAVISV GAATETEMKE KKARVEDALN ATRAAVEEGI VPGGGVAYLR
     CLGALGAVNL EGDEKLGLNI VKRALEEPAR QIAMNAGEEG SVIVQRVKSE TGAFGFDAET
     SQFCDLIEAG VIDPTKVTRT ALLNAASVSA LMLTTECMVS EIPKEDKGAP AGMGGMPPGG
     GMY
//

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