(data stored in ACNUC7421 zone)

SWISSPROT: A0LEQ4_SYNFM

ID   A0LEQ4_SYNFM            Unreviewed;       175 AA.
AC   A0LEQ4;
DT   12-DEC-2006, integrated into UniProtKB/TrEMBL.
DT   12-DEC-2006, sequence version 1.
DT   08-MAY-2019, entry version 66.
DE   RecName: Full=NADH-quinone oxidoreductase subunit J {ECO:0000256|RuleBase:RU004429};
DE            EC=7.1.1.- {ECO:0000256|RuleBase:RU004429};
GN   OrderedLocusNames=Sfum_0205 {ECO:0000313|EMBL:ABK15906.1};
OS   Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Syntrophobacterales;
OC   Syntrophobacteraceae; Syntrophobacter.
OX   NCBI_TaxID=335543 {ECO:0000313|EMBL:ABK15906.1, ECO:0000313|Proteomes:UP000001784};
RN   [1] {ECO:0000313|EMBL:ABK15906.1, ECO:0000313|Proteomes:UP000001784}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 10017 / MPOB {ECO:0000313|Proteomes:UP000001784};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Pitluck S., Goltsman E.G.,
RA   Martinez M., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Kim E., Boone D.R., Brockman F., Culley D., Ferry J., Gunsalus R.,
RA   McInerney M.J., Morrison M., Plugge C., Rohlin L., Scholten J.,
RA   Sieber J., Stams A.J.M., Worm P., Henstra A.M., Richardson P.;
RT   "Complete sequence of Syntrophobacter fumaroxidans MPOB.";
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: NDH-1 shuttles electrons from NADH, via FMN and iron-
CC       sulfur (Fe-S) centers, to quinones in the respiratory chain.
CC       Couples the redox reaction to proton translocation (for every two
CC       electrons transferred, four hydrogen ions are translocated across
CC       the cytoplasmic membrane), and thus conserves the redox energy in
CC       a proton gradient. {ECO:0000256|RuleBase:RU004429}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a quinone + 5 H(+)(in) + NADH = a quinol + 4 H(+)(out) +
CC         NAD(+); Xref=Rhea:RHEA:57888, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:24646, ChEBI:CHEBI:57540, ChEBI:CHEBI:57945,
CC         ChEBI:CHEBI:132124; Evidence={ECO:0000256|RuleBase:RU004429};
CC   -!- SUBCELLULAR LOCATION: Cell membrane
CC       {ECO:0000256|RuleBase:RU004429}; Multi-pass membrane protein
CC       {ECO:0000256|RuleBase:RU004429}.
CC   -!- SIMILARITY: Belongs to the complex I subunit 6 family.
CC       {ECO:0000256|RuleBase:RU004429}.
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DR   EMBL; CP000478; ABK15906.1; -; Genomic_DNA.
DR   RefSeq; WP_011697079.1; NC_008554.1.
DR   STRING; 335543.Sfum_0205; -.
DR   EnsemblBacteria; ABK15906; ABK15906; Sfum_0205.
DR   KEGG; sfu:Sfum_0205; -.
DR   eggNOG; ENOG4108435; Bacteria.
DR   eggNOG; ENOG410ZX6N; LUCA.
DR   KO; K00339; -.
DR   OMA; WPALILM; -.
DR   OrthoDB; 1683794at2; -.
DR   BioCyc; SFUM335543:G1G7I-208-MONOMER; -.
DR   Proteomes; UP000001784; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0048038; F:quinone binding; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.20.120.1200; -; 1.
DR   InterPro; IPR001457; NADH_UbQ/plastoQ_OxRdtase_su6.
DR   InterPro; IPR042106; Nuo/plastoQ_OxRdtase_6_NuoJ.
DR   Pfam; PF00499; Oxidored_q3; 1.
PE   3: Inferred from homology;
DR   PRODOM; A0LEQ4.
DR   SWISS-2DPAGE; A0LEQ4.
KW   Cell membrane {ECO:0000256|RuleBase:RU004429};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001784};
KW   Membrane {ECO:0000256|RuleBase:RU004429};
KW   NAD {ECO:0000256|RuleBase:RU004429};
KW   Quinone {ECO:0000256|RuleBase:RU004429};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001784};
KW   Transmembrane {ECO:0000256|RuleBase:RU004429};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU004429};
KW   Ubiquinone {ECO:0000313|EMBL:ABK15906.1}.
FT   TRANSMEM     13     32       Helical. {ECO:0000256|RuleBase:RU004429}.
FT   TRANSMEM     39     60       Helical. {ECO:0000256|RuleBase:RU004429}.
FT   TRANSMEM     66     87       Helical. {ECO:0000256|RuleBase:RU004429}.
FT   TRANSMEM     99    122       Helical. {ECO:0000256|RuleBase:RU004429}.
FT   TRANSMEM    142    169       Helical. {ECO:0000256|RuleBase:RU004429}.
SQ   SEQUENCE   175 AA;  18579 MW;  8D77909C26C2BB1B CRC64;
     MNVLTGMDAA AHAGFWIVVG LTLAGASFAV FPRNILHNVL GLILALSGIG GLYLSLGSFF
     MGLMQLLIYV GAICVAIVFA IMLSRPLHLE VPKREAPKVA MAVATSVVFL VAMVGVVLRT
     NWVPAVERGT DWSVEAIGDL LLTRYALVFE VISLILLIAI IGAIITAGFS RRLSS
//

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