(data stored in ACNUC7421 zone)

SWISSPROT: A0LER4_SYNFM

ID   A0LER4_SYNFM            Unreviewed;       254 AA.
AC   A0LER4;
DT   12-DEC-2006, integrated into UniProtKB/TrEMBL.
DT   12-DEC-2006, sequence version 1.
DT   08-MAY-2019, entry version 61.
DE   RecName: Full=Ribosomal RNA small subunit methyltransferase E {ECO:0000256|PIRNR:PIRNR015601};
DE            EC=2.1.1.193 {ECO:0000256|PIRNR:PIRNR015601};
GN   OrderedLocusNames=Sfum_0215 {ECO:0000313|EMBL:ABK15916.1};
OS   Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Syntrophobacterales;
OC   Syntrophobacteraceae; Syntrophobacter.
OX   NCBI_TaxID=335543 {ECO:0000313|EMBL:ABK15916.1, ECO:0000313|Proteomes:UP000001784};
RN   [1] {ECO:0000313|EMBL:ABK15916.1, ECO:0000313|Proteomes:UP000001784}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 10017 / MPOB {ECO:0000313|Proteomes:UP000001784};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Pitluck S., Goltsman E.G.,
RA   Martinez M., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Kim E., Boone D.R., Brockman F., Culley D., Ferry J., Gunsalus R.,
RA   McInerney M.J., Morrison M., Plugge C., Rohlin L., Scholten J.,
RA   Sieber J., Stams A.J.M., Worm P., Henstra A.M., Richardson P.;
RT   "Complete sequence of Syntrophobacter fumaroxidans MPOB.";
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Specifically methylates the N3 position of the uracil
CC       ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully
CC       assembled 30S ribosomal subunit. {ECO:0000256|PIRNR:PIRNR015601}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=S-adenosyl-L-methionine + uridine(1498) in 16S rRNA =
CC         H(+) + N(3)-methyluridine(1498) in 16S rRNA + S-adenosyl-L-
CC         homocysteine; Xref=Rhea:RHEA:42920, Rhea:RHEA-COMP:10283,
CC         Rhea:RHEA-COMP:10284, ChEBI:CHEBI:15378, ChEBI:CHEBI:57856,
CC         ChEBI:CHEBI:59789, ChEBI:CHEBI:65315, ChEBI:CHEBI:74502;
CC         EC=2.1.1.193; Evidence={ECO:0000256|PIRNR:PIRNR015601};
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|PIRNR:PIRNR015601}.
CC   -!- SIMILARITY: Belongs to the RNA methyltransferase RsmE family.
CC       {ECO:0000256|PIRNR:PIRNR015601}.
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DR   EMBL; CP000478; ABK15916.1; -; Genomic_DNA.
DR   RefSeq; WP_011697089.1; NC_008554.1.
DR   STRING; 335543.Sfum_0215; -.
DR   EnsemblBacteria; ABK15916; ABK15916; Sfum_0215.
DR   KEGG; sfu:Sfum_0215; -.
DR   eggNOG; ENOG4105QF0; Bacteria.
DR   eggNOG; COG1385; LUCA.
DR   HOGENOM; HOG000015265; -.
DR   KO; K09761; -.
DR   OMA; ERMEFTI; -.
DR   OrthoDB; 1490892at2; -.
DR   BioCyc; SFUM335543:G1G7I-218-MONOMER; -.
DR   Proteomes; UP000001784; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.1280.10; -; 1.
DR   InterPro; IPR029028; Alpha/beta_knot_MTases.
DR   InterPro; IPR015947; PUA-like_sf.
DR   InterPro; IPR006700; rRNA_ssu_MeTrfase-E.
DR   InterPro; IPR029026; tRNA_m1G_MTases_N.
DR   PANTHER; PTHR30027; PTHR30027; 1.
DR   Pfam; PF04452; Methyltrans_RNA; 1.
DR   PIRSF; PIRSF015601; MTase_slr0722; 1.
DR   SUPFAM; SSF75217; SSF75217; 1.
DR   SUPFAM; SSF88697; SSF88697; 1.
DR   TIGRFAMs; TIGR00046; TIGR00046; 1.
PE   3: Inferred from homology;
DR   PRODOM; A0LER4.
DR   SWISS-2DPAGE; A0LER4.
KW   Complete proteome {ECO:0000313|Proteomes:UP000001784};
KW   Cytoplasm {ECO:0000256|PIRNR:PIRNR015601};
KW   Methyltransferase {ECO:0000256|PIRNR:PIRNR015601};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001784};
KW   rRNA processing {ECO:0000256|PIRNR:PIRNR015601};
KW   S-adenosyl-L-methionine {ECO:0000256|PIRNR:PIRNR015601};
KW   Transferase {ECO:0000256|PIRNR:PIRNR015601}.
SQ   SEQUENCE   254 AA;  27827 MW;  29F82ABE8C4E0B59 CRC64;
     MTRKRFFVER AVPGEGTIDL GVDAAHHIEH VLRLRAGEEV ELIDGVGGGW LGAIVEAGTG
     TVRVRITGRL GPPAESSLNL SLALAFSRAD RMDLVLRQAT EIGVNRFIAF RSRRSQYALT
     GRAAGKRLER WQRIAREAVC QCGRLNVPEM VILSDVRELL AKIEQRERSG NLLRILAFER
     GNGKGIVDLH RAFPQCTEVM VAVGPEGGWS SEEAELLTRN GFHAVHLGPR ILRLETAAAI
     VLSSVQLLWG DLGA
//

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