(data stored in ACNUC7421 zone)

SWISSPROT: A0LFP3_SYNFM

ID   A0LFP3_SYNFM            Unreviewed;       477 AA.
AC   A0LFP3;
DT   12-DEC-2006, integrated into UniProtKB/TrEMBL.
DT   12-DEC-2006, sequence version 1.
DT   16-JAN-2019, entry version 75.
DE   SubName: Full=UDP-N-acetylmuramate--L-alanine ligase {ECO:0000313|EMBL:ABK16245.1};
DE            EC=6.3.2.8 {ECO:0000313|EMBL:ABK16245.1};
GN   OrderedLocusNames=Sfum_0546 {ECO:0000313|EMBL:ABK16245.1};
OS   Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Syntrophobacterales;
OC   Syntrophobacteraceae; Syntrophobacter.
OX   NCBI_TaxID=335543 {ECO:0000313|EMBL:ABK16245.1, ECO:0000313|Proteomes:UP000001784};
RN   [1] {ECO:0000313|EMBL:ABK16245.1, ECO:0000313|Proteomes:UP000001784}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 10017 / MPOB {ECO:0000313|Proteomes:UP000001784};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Pitluck S., Goltsman E.G.,
RA   Martinez M., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Kim E., Boone D.R., Brockman F., Culley D., Ferry J., Gunsalus R.,
RA   McInerney M.J., Morrison M., Plugge C., Rohlin L., Scholten J.,
RA   Sieber J., Stams A.J.M., Worm P., Henstra A.M., Richardson P.;
RT   "Complete sequence of Syntrophobacter fumaroxidans MPOB.";
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; CP000478; ABK16245.1; -; Genomic_DNA.
DR   STRING; 335543.Sfum_0546; -.
DR   EnsemblBacteria; ABK16245; ABK16245; Sfum_0546.
DR   KEGG; sfu:Sfum_0546; -.
DR   eggNOG; ENOG4105DFU; Bacteria.
DR   eggNOG; COG0773; LUCA.
DR   HOGENOM; HOG000256032; -.
DR   KO; K02558; -.
DR   OMA; CDANVYP; -.
DR   Proteomes; UP000001784; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0008763; F:UDP-N-acetylmuramate-L-alanine ligase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.40.1190.10; -; 1.
DR   Gene3D; 3.90.190.20; -; 1.
DR   InterPro; IPR036565; Mur-like_cat_sf.
DR   InterPro; IPR004101; Mur_ligase_C.
DR   InterPro; IPR036615; Mur_ligase_C_dom_sf.
DR   InterPro; IPR013221; Mur_ligase_cen.
DR   InterPro; IPR000713; Mur_ligase_N.
DR   Pfam; PF01225; Mur_ligase; 1.
DR   Pfam; PF02875; Mur_ligase_C; 1.
DR   Pfam; PF08245; Mur_ligase_M; 1.
DR   SUPFAM; SSF53244; SSF53244; 1.
DR   SUPFAM; SSF53623; SSF53623; 1.
PE   4: Predicted;
DR   PRODOM; A0LFP3.
DR   SWISS-2DPAGE; A0LFP3.
KW   Complete proteome {ECO:0000313|Proteomes:UP000001784};
KW   Ligase {ECO:0000313|EMBL:ABK16245.1};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001784};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM      9     26       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN        8    105       Mur_ligase. {ECO:0000259|Pfam:PF01225}.
FT   DOMAIN      115    302       Mur_ligase_M. {ECO:0000259|Pfam:PF08245}.
FT   DOMAIN      322    371       Mur_ligase_C. {ECO:0000259|Pfam:PF02875}.
SQ   SEQUENCE   477 AA;  52509 MW;  9E97FDFA376E5FA0 CRC64;
     MRRKNSKTIY LLGIGGIAMG TLATMLTEKG FNVTGSDLNL YPPMSTHLET LGIPVCQGYD
     AANPEKCAPD LVIIGNAIRR TNPEAEYVLS HGLPYLSMPQ AIAEFFLCAH KSMVVAGTHG
     KSTTSSLLSW VLSRGGLDPS VFVGAFIKNW NSSYRIGRGP FMVIEGDEYD TAFFDKGPKF
     LHYSPWIGIV TSVEFDHADI FTDFEAVRRA FRSFARLIQP DGHLILNADD ANCLALAKES
     RGRVTTYGWS RTADWRIVDM IHTDGRIRFT YENPLSRGTE SILTRMPGRH NVSNSMAVMA
     AASLAGLDRN AVQDGLLTFE GVKRRQDILG EIGGILVMDD FAHHPTAVRE TIQALKDFYP
     RRRIFCAFEP RTNSSRRSVF QQAYTTAFDD AFCICIKHPP GMDAIPREER LDVQKLVADI
     AERGKECHGF ASAEDLIGFL VDHCASGDLV VCMSNGSFDG LPHGLCTALA QKHAGAS
//

If you have problems or comments...

PBIL Back to PBIL home page