(data stored in ACNUC7421 zone)

SWISSPROT: A0KF18_AERHH

ID   A0KF18_AERHH            Unreviewed;       433 AA.
AC   A0KF18;
DT   12-DEC-2006, integrated into UniProtKB/TrEMBL.
DT   12-DEC-2006, sequence version 1.
DT   08-MAY-2019, entry version 95.
DE   SubName: Full=Osmolarity sensor protein EnvZ {ECO:0000313|EMBL:ABK35998.1};
DE            EC=2.7.3.- {ECO:0000313|EMBL:ABK35998.1};
GN   Name=envZ {ECO:0000313|EMBL:ABK35998.1};
GN   OrderedLocusNames=AHA_0306 {ECO:0000313|EMBL:ABK35998.1};
OS   Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 /
OS   JCM 1027 / KCTC 2358 / NCIMB 9240).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Aeromonadales;
OC   Aeromonadaceae; Aeromonas.
OX   NCBI_TaxID=380703 {ECO:0000313|EMBL:ABK35998.1, ECO:0000313|Proteomes:UP000000756};
RN   [1] {ECO:0000313|EMBL:ABK35998.1, ECO:0000313|Proteomes:UP000000756}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 7966 / DSM 30187 / JCM 1027 / KCTC 2358 / NCIMB 9240
RC   {ECO:0000313|Proteomes:UP000000756};
RX   PubMed=16980456; DOI=10.1128/JB.00621-06;
RA   Seshadri R., Joseph S.W., Chopra A.K., Sha J., Shaw J., Graf J.,
RA   Haft D., Wu M., Ren Q., Rosovitz M.J., Madupu R., Tallon L., Kim M.,
RA   Jin S., Vuong H., Stine O.C., Ali A., Horneman A.J., Heidelberg J.F.;
RT   "Genome sequence of Aeromonas hydrophila ATCC 7966T: jack of all
RT   trades.";
RL   J. Bacteriol. 188:8272-8282(2006).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC         histidine.; EC=2.7.13.3;
CC         Evidence={ECO:0000256|SAAS:SAAS01126420};
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; CP000462; ABK35998.1; -; Genomic_DNA.
DR   RefSeq; WP_011704311.1; NC_008570.1.
DR   RefSeq; YP_854836.1; NC_008570.1.
DR   STRING; 380703.AHA_0306; -.
DR   EnsemblBacteria; ABK35998; ABK35998; AHA_0306.
DR   GeneID; 4488765; -.
DR   KEGG; aha:AHA_0306; -.
DR   PATRIC; fig|380703.7.peg.295; -.
DR   eggNOG; ENOG4105E0F; Bacteria.
DR   eggNOG; ENOG410XTWD; LUCA.
DR   HOGENOM; HOG000218774; -.
DR   KO; K07638; -.
DR   OMA; WIRPPQA; -.
DR   BioCyc; AHYD380703:G1G7B-307-MONOMER; -.
DR   Proteomes; UP000000756; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   CDD; cd06225; HAMP; 1.
DR   CDD; cd00075; HATPase_c; 1.
DR   CDD; cd00082; HisKA; 1.
DR   Gene3D; 3.30.565.10; -; 1.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR005467; His_kinase_dom.
DR   InterPro; IPR003661; HisK_dim/P.
DR   InterPro; IPR036097; HisK_dim/P_sf.
DR   InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF02518; HATPase_c; 1.
DR   Pfam; PF00512; HisKA; 1.
DR   PRINTS; PR00344; BCTRLSENSOR.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM00387; HATPase_c; 1.
DR   SMART; SM00388; HisKA; 1.
DR   SUPFAM; SSF47384; SSF47384; 1.
DR   SUPFAM; SSF55874; SSF55874; 1.
DR   PROSITE; PS50885; HAMP; 1.
DR   PROSITE; PS50109; HIS_KIN; 1.
PE   4: Predicted;
DR   PRODOM; A0KF18.
DR   SWISS-2DPAGE; A0KF18.
KW   ATP-binding {ECO:0000256|SAAS:SAAS00925949};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000756};
KW   Kinase {ECO:0000256|SAAS:SAAS01003914};
KW   Membrane {ECO:0000256|SAAS:SAAS00925724, ECO:0000256|SAM:Phobius};
KW   Nucleotide-binding {ECO:0000256|SAAS:SAAS00925310};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000756};
KW   Transferase {ECO:0000256|SAAS:SAAS01003669,
KW   ECO:0000313|EMBL:ABK35998.1};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00926038,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00926160,
KW   ECO:0000256|SAM:Phobius};
KW   Two-component regulatory system {ECO:0000256|SAAS:SAAS00924981}.
FT   TRANSMEM    147    166       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      167    219       HAMP. {ECO:0000259|PROSITE:PS50885}.
FT   DOMAIN      227    427       Histidine kinase. {ECO:0000259|PROSITE:
FT                                PS50109}.
SQ   SEQUENCE   433 AA;  48718 MW;  48F1A34C06D435E6 CRC64;
     MSSMFSRMLW FLAAVLVVYQ FVSYATFYNY LLAPTVKQIS HLLANQVKLI FPVESNQLAL
     SEDAEALVYV ATGSDIYTQT EAEQHGLNES KPYTYLEESI SRELGGKTKV RVEIQDHYII
     WIQPPQANKV WVRIPLTEIE DDDIEPLILY MSVLLVVTLF AAWRFARQLV RPLEDLEAGA
     VAVARGNFPD ALGEQGSREV RRLTRTFNHM SSSIKGLIEE RNLMMAGVSH DLRTPLTRIR
     LATEMMSSGD EYLKESINAD IDESNGIIDQ FIDYIRPDEG LDTQQIDLTQ LIHDSLLVQT
     DQGLEVELEL PAEAVRVACN PISIRRILNN LSGNSLRYGA SRLQAELKDD GHWVRLRLSD
     DGPGIPEQDY YRVLKPFTQG NEARTGSGSG LGLAIVAKIV SQHHGTIRLG RSELGGLLVE
     IRLPKNQPLE WID
//

If you have problems or comments...

PBIL Back to PBIL home page