(data stored in ACNUC7421 zone)

SWISSPROT: A0KF81_AERHH

ID   A0KF81_AERHH            Unreviewed;       284 AA.
AC   A0KF81;
DT   12-DEC-2006, integrated into UniProtKB/TrEMBL.
DT   12-DEC-2006, sequence version 1.
DT   08-MAY-2019, entry version 95.
DE   RecName: Full=RNA polymerase sigma factor RpoH {ECO:0000256|HAMAP-Rule:MF_00961};
DE   AltName: Full=RNA polymerase sigma-32 factor {ECO:0000256|HAMAP-Rule:MF_00961};
GN   Name=rpoH {ECO:0000256|HAMAP-Rule:MF_00961,
GN   ECO:0000313|EMBL:ABK37097.1};
GN   OrderedLocusNames=AHA_0374 {ECO:0000313|EMBL:ABK37097.1};
OS   Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 /
OS   JCM 1027 / KCTC 2358 / NCIMB 9240).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Aeromonadales;
OC   Aeromonadaceae; Aeromonas.
OX   NCBI_TaxID=380703 {ECO:0000313|EMBL:ABK37097.1, ECO:0000313|Proteomes:UP000000756};
RN   [1] {ECO:0000313|EMBL:ABK37097.1, ECO:0000313|Proteomes:UP000000756}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 7966 / DSM 30187 / JCM 1027 / KCTC 2358 / NCIMB 9240
RC   {ECO:0000313|Proteomes:UP000000756};
RX   PubMed=16980456; DOI=10.1128/JB.00621-06;
RA   Seshadri R., Joseph S.W., Chopra A.K., Sha J., Shaw J., Graf J.,
RA   Haft D., Wu M., Ren Q., Rosovitz M.J., Madupu R., Tallon L., Kim M.,
RA   Jin S., Vuong H., Stine O.C., Ali A., Horneman A.J., Heidelberg J.F.;
RT   "Genome sequence of Aeromonas hydrophila ATCC 7966T: jack of all
RT   trades.";
RL   J. Bacteriol. 188:8272-8282(2006).
CC   -!- FUNCTION: Sigma factors are initiation factors that promote the
CC       attachment of RNA polymerase to specific initiation sites and are
CC       then released. This sigma factor is involved in regulation of
CC       expression of heat shock genes. {ECO:0000256|HAMAP-Rule:MF_00961}.
CC   -!- SUBUNIT: Interacts with the RNA polymerase core enzyme.
CC       {ECO:0000256|HAMAP-Rule:MF_00961}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00961}.
CC   -!- SIMILARITY: Belongs to the sigma-70 factor family. RpoH subfamily.
CC       {ECO:0000256|HAMAP-Rule:MF_00961}.
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DR   EMBL; CP000462; ABK37097.1; -; Genomic_DNA.
DR   RefSeq; WP_011704351.1; NC_008570.1.
DR   RefSeq; YP_854903.1; NC_008570.1.
DR   STRING; 380703.AHA_0374; -.
DR   EnsemblBacteria; ABK37097; ABK37097; AHA_0374.
DR   GeneID; 4490820; -.
DR   KEGG; aha:AHA_0374; -.
DR   PATRIC; fig|380703.7.peg.361; -.
DR   eggNOG; ENOG4105DEK; Bacteria.
DR   eggNOG; COG0568; LUCA.
DR   HOGENOM; HOG000270269; -.
DR   KO; K03089; -.
DR   OMA; YQRWLAE; -.
DR   BioCyc; AHYD380703:G1G7B-375-MONOMER; -.
DR   Proteomes; UP000000756; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0016987; F:sigma factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0009408; P:response to heat; IEA:UniProtKB-UniRule.
DR   GO; GO:0001123; P:transcription initiation from bacterial-type RNA polymerase promoter; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.10.10; -; 1.
DR   HAMAP; MF_00961; Sigma70_RpoH; 1.
DR   InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR   InterPro; IPR000943; RNA_pol_sigma70.
DR   InterPro; IPR009042; RNA_pol_sigma70_r1_2.
DR   InterPro; IPR007627; RNA_pol_sigma70_r2.
DR   InterPro; IPR007630; RNA_pol_sigma70_r4.
DR   InterPro; IPR013325; RNA_pol_sigma_r2.
DR   InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR   InterPro; IPR012759; RNA_pol_sigma_RpoH_proteobac.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   Pfam; PF00140; Sigma70_r1_2; 1.
DR   Pfam; PF04542; Sigma70_r2; 1.
DR   Pfam; PF04545; Sigma70_r4; 1.
DR   PIRSF; PIRSF000770; RNA_pol_sigma-SigE/K; 1.
DR   PRINTS; PR00046; SIGMA70FCT.
DR   SUPFAM; SSF88659; SSF88659; 1.
DR   SUPFAM; SSF88946; SSF88946; 1.
DR   TIGRFAMs; TIGR02392; rpoH_proteo; 1.
DR   TIGRFAMs; TIGR02937; sigma70-ECF; 1.
DR   PROSITE; PS00715; SIGMA70_1; 1.
DR   PROSITE; PS00716; SIGMA70_2; 1.
PE   3: Inferred from homology;
DR   PRODOM; A0KF81.
DR   SWISS-2DPAGE; A0KF81.
KW   Complete proteome {ECO:0000313|Proteomes:UP000000756};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00961};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00961,
KW   ECO:0000256|SAAS:SAAS00611263};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000756};
KW   Sigma factor {ECO:0000256|HAMAP-Rule:MF_00961,
KW   ECO:0000256|SAAS:SAAS00611278};
KW   Stress response {ECO:0000256|HAMAP-Rule:MF_00961};
KW   Transcription {ECO:0000256|HAMAP-Rule:MF_00961,
KW   ECO:0000256|SAAS:SAAS00611290};
KW   Transcription regulation {ECO:0000256|HAMAP-Rule:MF_00961,
KW   ECO:0000256|SAAS:SAAS00611294}.
FT   DOMAIN       78     91       RNA_pol_sigma70. {ECO:0000259|PROSITE:
FT                                PS00715}.
FT   DOMAIN      252    278       RNA_pol_sigma70. {ECO:0000259|PROSITE:
FT                                PS00716}.
FT   DNA_BIND    253    272       H-T-H motif. {ECO:0000256|HAMAP-Rule:
FT                                MF_00961}.
FT   REGION       54    123       Sigma-70 factor domain-2.
FT                                {ECO:0000256|HAMAP-Rule:MF_00961}.
FT   REGION      228    280       Sigma-70 factor domain-4.
FT                                {ECO:0000256|HAMAP-Rule:MF_00961}.
FT   MOTIF        78     81       Interaction with polymerase core subunit
FT                                RpoC. {ECO:0000256|HAMAP-Rule:MF_00961}.
SQ   SEQUENCE   284 AA;  31908 MW;  323C726C53282577 CRC64;
     MGTSLQRTMA LIPQGSLEGY IQAVNSIPVL SAEEERELAE RLQQGGDLEA ARQLVMSHLR
     FVVHVAKSYA GYGLPQADLV QEGNIGLMKA VKRFDPSVGV RLVSFAVHWI KAEIHEYVLR
     NWRMVKVATT KAQRKLFFNL RKSKKRLGWL NHEEVQAVAA DLGVSAADVT EMEARMSNYD
     QAFDLVGDDE EEGGFAPVHY LEDKSSDLAA TIENDNWDDH ATRRLSSALA TLDERSQHII
     RARWLDDESK TTLQELADTY GVSAERVRQL EKNALKKLKD AMEA
//

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