(data stored in ACNUC7421 zone)

SWISSPROT: A0KEF5_AERHH

ID   A0KEF5_AERHH            Unreviewed;       138 AA.
AC   A0KEF5;
DT   12-DEC-2006, integrated into UniProtKB/TrEMBL.
DT   12-DEC-2006, sequence version 1.
DT   11-DEC-2019, entry version 86.
DE   RecName: Full=Putative fluoride ion transporter CrcB {ECO:0000256|HAMAP-Rule:MF_00454};
GN   Name=crcB {ECO:0000256|HAMAP-Rule:MF_00454,
GN   ECO:0000313|EMBL:ABK37803.1};
GN   OrderedLocusNames=AHA_0083 {ECO:0000313|EMBL:ABK37803.1};
OS   Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / JCM
OS   1027 / KCTC 2358 / NCIMB 9240).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Aeromonadales;
OC   Aeromonadaceae; Aeromonas.
OX   NCBI_TaxID=380703 {ECO:0000313|EMBL:ABK37803.1, ECO:0000313|Proteomes:UP000000756};
RN   [1] {ECO:0000313|EMBL:ABK37803.1, ECO:0000313|Proteomes:UP000000756}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 7966 / DSM 30187 / JCM 1027 / KCTC 2358 / NCIMB 9240
RC   {ECO:0000313|Proteomes:UP000000756};
RX   PubMed=16980456; DOI=10.1128/JB.00621-06;
RA   Seshadri R., Joseph S.W., Chopra A.K., Sha J., Shaw J., Graf J., Haft D.,
RA   Wu M., Ren Q., Rosovitz M.J., Madupu R., Tallon L., Kim M., Jin S.,
RA   Vuong H., Stine O.C., Ali A., Horneman A.J., Heidelberg J.F.;
RT   "Genome sequence of Aeromonas hydrophila ATCC 7966T: jack of all trades.";
RL   J. Bacteriol. 188:8272-8282(2006).
CC   -!- FUNCTION: Important for reducing fluoride concentration in the cell,
CC       thus reducing its toxicity. {ECO:0000256|HAMAP-Rule:MF_00454,
CC       ECO:0000256|SAAS:SAAS00388086}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000256|HAMAP-
CC       Rule:MF_00454}; Multi-pass membrane protein {ECO:0000256|HAMAP-
CC       Rule:MF_00454}.
CC   -!- SIMILARITY: Belongs to the CrcB (TC 9.B.71) family. {ECO:0000256|HAMAP-
CC       Rule:MF_00454, ECO:0000256|SAAS:SAAS00573618}.
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DR   EMBL; CP000462; ABK37803.1; -; Genomic_DNA.
DR   RefSeq; WP_011704115.1; NC_008570.1.
DR   RefSeq; YP_854605.1; NC_008570.1.
DR   STRING; 380703.AHA_0083; -.
DR   EnsemblBacteria; ABK37803; ABK37803; AHA_0083.
DR   GeneID; 4490978; -.
DR   KEGG; aha:AHA_0083; -.
DR   PATRIC; fig|380703.7.peg.74; -.
DR   eggNOG; ENOG4105WMR; Bacteria.
DR   eggNOG; COG0239; LUCA.
DR   HOGENOM; HOG000052573; -.
DR   KO; K06199; -.
DR   OMA; FLMFESF; -.
DR   BioCyc; AHYD380703:G1G7B-83-MONOMER; -.
DR   Proteomes; UP000000756; Chromosome.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0015103; F:inorganic anion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00454; CrcB; 1.
DR   InterPro; IPR003691; CrcB.
DR   PANTHER; PTHR28259; PTHR28259; 1.
DR   Pfam; PF02537; CRCB; 1.
DR   TIGRFAMs; TIGR00494; crcB; 1.
PE   3: Inferred from homology;
DR   PRODOM; A0KEF5.
DR   SWISS-2DPAGE; A0KEF5.
KW   Cell inner membrane {ECO:0000256|HAMAP-Rule:MF_00454};
KW   Cell membrane {ECO:0000256|HAMAP-Rule:MF_00454,
KW   ECO:0000256|SAAS:SAAS00702610};
KW   Membrane {ECO:0000256|HAMAP-Rule:MF_00454, ECO:0000256|SAAS:SAAS00702614};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000756};
KW   Transmembrane {ECO:0000256|HAMAP-Rule:MF_00454,
KW   ECO:0000256|SAAS:SAAS00702612};
KW   Transmembrane helix {ECO:0000256|HAMAP-Rule:MF_00454,
KW   ECO:0000256|SAAS:SAAS00702611};
KW   Transport {ECO:0000256|HAMAP-Rule:MF_00454, ECO:0000256|SAAS:SAAS00702613}.
FT   TRANSMEM        16..34
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_00454"
FT   TRANSMEM        46..69
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_00454"
FT   TRANSMEM        81..104
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_00454"
FT   TRANSMEM        116..135
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_00454"
SQ   SEQUENCE   138 AA;  14712 MW;  78A731AA7D1D9E72 CRC64;
     MHNVGPILWR HAPMQTWLYV AAGGAIGACL RFGIAELMAL LLGRHFPYGT LMVNVVGSFI
     MGIAFALISH GHVVEHPLKP LLMVGILGAL TTFSSFALDT VVLAQQGAYL KAALNIGLNL
     FLCLAMVVLG MQLVASRV
//

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