(data stored in ACNUC7421 zone)

SWISSPROT: A0KFU5_AERHH

ID   A0KFU5_AERHH            Unreviewed;       107 AA.
AC   A0KFU5;
DT   12-DEC-2006, integrated into UniProtKB/TrEMBL.
DT   12-DEC-2006, sequence version 1.
DT   08-MAY-2019, entry version 80.
DE   RecName: Full=Met repressor {ECO:0000256|SAAS:SAAS00343455};
GN   Name=metJ {ECO:0000313|EMBL:ABK38234.1};
GN   OrderedLocusNames=AHA_0588 {ECO:0000313|EMBL:ABK38234.1};
OS   Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 /
OS   JCM 1027 / KCTC 2358 / NCIMB 9240).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Aeromonadales;
OC   Aeromonadaceae; Aeromonas.
OX   NCBI_TaxID=380703 {ECO:0000313|EMBL:ABK38234.1, ECO:0000313|Proteomes:UP000000756};
RN   [1] {ECO:0000313|EMBL:ABK38234.1, ECO:0000313|Proteomes:UP000000756}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 7966 / DSM 30187 / JCM 1027 / KCTC 2358 / NCIMB 9240
RC   {ECO:0000313|Proteomes:UP000000756};
RX   PubMed=16980456; DOI=10.1128/JB.00621-06;
RA   Seshadri R., Joseph S.W., Chopra A.K., Sha J., Shaw J., Graf J.,
RA   Haft D., Wu M., Ren Q., Rosovitz M.J., Madupu R., Tallon L., Kim M.,
RA   Jin S., Vuong H., Stine O.C., Ali A., Horneman A.J., Heidelberg J.F.;
RT   "Genome sequence of Aeromonas hydrophila ATCC 7966T: jack of all
RT   trades.";
RL   J. Bacteriol. 188:8272-8282(2006).
CC   -!- FUNCTION: This regulatory protein, when combined with SAM (S-
CC       adenosylmethionine) represses the expression of the methionine
CC       regulon and of enzymes involved in SAM synthesis.
CC       {ECO:0000256|SAAS:SAAS00343434}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000256|SAAS:SAAS00343435}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|SAAS:SAAS00012459}.
CC   -!- SIMILARITY: Belongs to the MetJ family.
CC       {ECO:0000256|SAAS:SAAS00539576}.
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DR   EMBL; CP000462; ABK38234.1; -; Genomic_DNA.
DR   RefSeq; WP_005308521.1; NC_008570.1.
DR   RefSeq; YP_855121.1; NC_008570.1.
DR   STRING; 380703.AHA_0588; -.
DR   EnsemblBacteria; ABK38234; ABK38234; AHA_0588.
DR   GeneID; 4489255; -.
DR   KEGG; aha:AHA_0588; -.
DR   PATRIC; fig|380703.7.peg.584; -.
DR   eggNOG; ENOG4105GGQ; Bacteria.
DR   eggNOG; COG3060; LUCA.
DR   HOGENOM; HOG000271582; -.
DR   KO; K03764; -.
DR   OMA; KWNGEYI; -.
DR   BioCyc; AHYD380703:G1G7B-589-MONOMER; -.
DR   Proteomes; UP000000756; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.140.10; -; 1.
DR   InterPro; IPR002084; Met_repressor_MetJ.
DR   InterPro; IPR023453; Met_repressor_MetJ_dom_sf.
DR   InterPro; IPR010985; Ribbon_hlx_hlx.
DR   Pfam; PF01340; MetJ; 1.
DR   ProDom; PD020365; Met_repressor_MetJ; 1.
DR   SUPFAM; SSF47598; SSF47598; 1.
PE   3: Inferred from homology;
DR   PRODOM; A0KFU5.
DR   SWISS-2DPAGE; A0KFU5.
KW   Amino-acid biosynthesis {ECO:0000256|SAAS:SAAS00422005};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000756};
KW   Cytoplasm {ECO:0000256|SAAS:SAAS00012454};
KW   DNA-binding {ECO:0000256|SAAS:SAAS00422008};
KW   Methionine biosynthesis {ECO:0000256|SAAS:SAAS00106923};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000756};
KW   Repressor {ECO:0000256|SAAS:SAAS00422009};
KW   Transcription {ECO:0000256|SAAS:SAAS00422006};
KW   Transcription regulation {ECO:0000256|SAAS:SAAS00422010}.
SQ   SEQUENCE   107 AA;  12091 MW;  B3D3283538B2C704 CRC64;
     MGTEWNGDYV SPYAEHGKKS EQVKKITVSI PLKVLKVLTD ERTRRQVNNL RHATNSELLC
     EAFLHAFTGQ PLPCDEDLRK DHPDSVPAEA RAIMEALGKE IEDFDAE
//

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