(data stored in ACNUC7421 zone)

SWISSPROT: A0KFV2_AERHH

ID   A0KFV2_AERHH            Unreviewed;       338 AA.
AC   A0KFV2;
DT   12-DEC-2006, integrated into UniProtKB/TrEMBL.
DT   12-DEC-2006, sequence version 1.
DT   08-MAY-2019, entry version 84.
DE   RecName: Full=Ornithine carbamoyltransferase {ECO:0000256|SAAS:SAAS00393033};
DE            EC=2.1.3.3 {ECO:0000256|SAAS:SAAS00393033};
GN   Name=argF-1 {ECO:0000313|EMBL:ABK39334.1};
GN   OrderedLocusNames=AHA_0595 {ECO:0000313|EMBL:ABK39334.1};
OS   Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 /
OS   JCM 1027 / KCTC 2358 / NCIMB 9240).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Aeromonadales;
OC   Aeromonadaceae; Aeromonas.
OX   NCBI_TaxID=380703 {ECO:0000313|EMBL:ABK39334.1, ECO:0000313|Proteomes:UP000000756};
RN   [1] {ECO:0000313|EMBL:ABK39334.1, ECO:0000313|Proteomes:UP000000756}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 7966 / DSM 30187 / JCM 1027 / KCTC 2358 / NCIMB 9240
RC   {ECO:0000313|Proteomes:UP000000756};
RX   PubMed=16980456; DOI=10.1128/JB.00621-06;
RA   Seshadri R., Joseph S.W., Chopra A.K., Sha J., Shaw J., Graf J.,
RA   Haft D., Wu M., Ren Q., Rosovitz M.J., Madupu R., Tallon L., Kim M.,
RA   Jin S., Vuong H., Stine O.C., Ali A., Horneman A.J., Heidelberg J.F.;
RT   "Genome sequence of Aeromonas hydrophila ATCC 7966T: jack of all
RT   trades.";
RL   J. Bacteriol. 188:8272-8282(2006).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=carbamoyl phosphate + L-ornithine = H(+) + L-citrulline +
CC         phosphate; Xref=Rhea:RHEA:19513, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:46911, ChEBI:CHEBI:57743,
CC         ChEBI:CHEBI:58228; EC=2.1.3.3;
CC         Evidence={ECO:0000256|SAAS:SAAS01125822};
CC   -!- SIMILARITY: Belongs to the ATCase/OTCase family.
CC       {ECO:0000256|RuleBase:RU003634, ECO:0000256|SAAS:SAAS00578869}.
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DR   EMBL; CP000462; ABK39334.1; -; Genomic_DNA.
DR   RefSeq; WP_011704562.1; NC_008570.1.
DR   RefSeq; YP_855128.1; NC_008570.1.
DR   STRING; 380703.AHA_0595; -.
DR   EnsemblBacteria; ABK39334; ABK39334; AHA_0595.
DR   GeneID; 4489262; -.
DR   KEGG; aha:AHA_0595; -.
DR   PATRIC; fig|380703.7.peg.592; -.
DR   eggNOG; ENOG4105DBV; Bacteria.
DR   eggNOG; COG0078; LUCA.
DR   HOGENOM; HOG000022686; -.
DR   KO; K00611; -.
DR   OMA; NLSRWCD; -.
DR   BioCyc; AHYD380703:G1G7B-596-MONOMER; -.
DR   Proteomes; UP000000756; Chromosome.
DR   GO; GO:0016597; F:amino acid binding; IEA:InterPro.
DR   GO; GO:0004585; F:ornithine carbamoyltransferase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.40.50.1370; -; 2.
DR   InterPro; IPR006132; Asp/Orn_carbamoyltranf_P-bd.
DR   InterPro; IPR006130; Asp/Orn_carbamoylTrfase.
DR   InterPro; IPR036901; Asp/Orn_carbamoylTrfase_sf.
DR   InterPro; IPR006131; Asp_carbamoyltransf_Asp/Orn-bd.
DR   InterPro; IPR002292; Orn/put_carbamltrans.
DR   Pfam; PF00185; OTCace; 1.
DR   Pfam; PF02729; OTCace_N; 1.
DR   PRINTS; PR00100; AOTCASE.
DR   PRINTS; PR00102; OTCASE.
DR   SUPFAM; SSF53671; SSF53671; 1.
DR   TIGRFAMs; TIGR00658; orni_carb_tr; 1.
PE   3: Inferred from homology;
DR   PRODOM; A0KFV2.
DR   SWISS-2DPAGE; A0KFV2.
KW   Complete proteome {ECO:0000313|Proteomes:UP000000756};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000756};
KW   Transferase {ECO:0000256|RuleBase:RU003634,
KW   ECO:0000256|SAAS:SAAS00470455, ECO:0000313|EMBL:ABK39334.1}.
FT   DOMAIN       37    175       OTCace_N. {ECO:0000259|Pfam:PF02729}.
FT   DOMAIN      182    333       OTCace. {ECO:0000259|Pfam:PF00185}.
SQ   SEQUENCE   338 AA;  36809 MW;  47D2FB29F1D72D72 CRC64;
     MSPAGATRIS CSSCWLAARS APKWLFDLHR SKEHPMQHLL KDSDLNKAQI EALIALGKAV
     KADPKKYGQA LAGKSVVTLF EKPSLRTRVT FDIGIAKLGG HSVYLDQQNG ALGKRESVQD
     FAANLSRWCD AIVARVFDHQ TLVELAEHGT VPVVNSLCNL YHPCQGLADF MTISEHYGDL
     SKVKLAYLGD GNNVSHSLLL LGATLGTNVT LVCPKGHGPD TQIFLQAQAL AAQSGATIHI
     SDDVAAIEGF DVAYTDTWVS MGDNTPMEQV KDIFMPYQIN QALLDRTGIQ HVLHCQPAHR
     ELEITSQVMD GPGSLIMDEA ENRMHIQNAV LLTLLGHK
//

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