(data stored in ACNUC7421 zone)

SWISSPROT: MNMG_PARDP

ID   MNMG_PARDP              Reviewed;         619 AA.
AC   A1AXX7;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 1.
DT   08-MAY-2019, entry version 78.
DE   RecName: Full=tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG {ECO:0000255|HAMAP-Rule:MF_00129};
DE   AltName: Full=Glucose-inhibited division protein A {ECO:0000255|HAMAP-Rule:MF_00129};
GN   Name=mnmG {ECO:0000255|HAMAP-Rule:MF_00129};
GN   Synonyms=gidA {ECO:0000255|HAMAP-Rule:MF_00129};
GN   OrderedLocusNames=Pden_0004;
OS   Paracoccus denitrificans (strain Pd 1222).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
OC   Rhodobacteraceae; Paracoccus.
OX   NCBI_TaxID=318586;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Pd 1222;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H.,
RA   Pitluck S., Munk A.C., Brettin T., Bruce D., Han C., Tapia R.,
RA   Gilna P., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Lykidis A., Spiro S., Richardson D.J., Moir J.W.B., Ferguson S.J.,
RA   van Spanning R.J.M., Richardson P.;
RT   "Complete sequence of chromosome 1 of Paracoccus denitrificans
RT   PD1222.";
RL   Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: NAD-binding protein involved in the addition of a
CC       carboxymethylaminomethyl (cmnm) group at the wobble position (U34)
CC       of certain tRNAs, forming tRNA-cmnm(5)s(2)U34. {ECO:0000255|HAMAP-
CC       Rule:MF_00129}.
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00129};
CC   -!- SUBUNIT: Homodimer. Heterotetramer of two MnmE and two MnmG
CC       subunits. {ECO:0000255|HAMAP-Rule:MF_00129}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00129}.
CC   -!- SIMILARITY: Belongs to the MnmG family. {ECO:0000255|HAMAP-
CC       Rule:MF_00129}.
DR   EMBL; CP000489; ABL68121.1; -; Genomic_DNA.
DR   RefSeq; WP_011746354.1; NC_008686.1.
DR   SMR; A1AXX7; -.
DR   STRING; 318586.Pden_0004; -.
DR   PRIDE; A1AXX7; -.
DR   EnsemblBacteria; ABL68121; ABL68121; Pden_0004.
DR   KEGG; pde:Pden_0004; -.
DR   eggNOG; ENOG4107RE5; Bacteria.
DR   eggNOG; COG0445; LUCA.
DR   HOGENOM; HOG000201059; -.
DR   KO; K03495; -.
DR   OMA; FRPGYAI; -.
DR   BioCyc; PDEN318586:G1GW1-4-MONOMER; -.
DR   Proteomes; UP000000361; Chromosome 1.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0002098; P:tRNA wobble uridine modification; IEA:InterPro.
DR   Gene3D; 3.50.50.60; -; 2.
DR   HAMAP; MF_00129; MnmG_GidA; 1.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR026904; GidA-assoc_3.
DR   InterPro; IPR004416; MnmG.
DR   InterPro; IPR002218; MnmG-rel.
DR   InterPro; IPR020595; MnmG-rel_CS.
DR   PANTHER; PTHR11806; PTHR11806; 1.
DR   PANTHER; PTHR11806:SF0; PTHR11806:SF0; 1.
DR   Pfam; PF13932; GIDA_assoc; 1.
DR   SUPFAM; SSF51905; SSF51905; 1.
DR   TIGRFAMs; TIGR00136; gidA; 1.
DR   PROSITE; PS01280; GIDA_1; 1.
DR   PROSITE; PS01281; GIDA_2; 1.
PE   3: Inferred from homology;
DR   PRODOM; A1AXX7.
DR   SWISS-2DPAGE; A1AXX7.
KW   Complete proteome; Cytoplasm; FAD; Flavoprotein; NAD;
KW   Reference proteome; tRNA processing.
FT   CHAIN         1    619       tRNA uridine 5-carboxymethylaminomethyl
FT                                modification enzyme MnmG.
FT                                /FTId=PRO_1000016634.
FT   NP_BIND      10     15       FAD. {ECO:0000255|HAMAP-Rule:MF_00129}.
FT   NP_BIND     269    283       NAD. {ECO:0000255|HAMAP-Rule:MF_00129}.
SQ   SEQUENCE   619 AA;  67252 MW;  6EB03030EB3C10B8 CRC64;
     MKQFDVIVIG GGHAGVEAAM AAARMGVKTA LVTLHRDDIG TMSCNPAIGG LGKGHLVREI
     DALDGVMGKL ADTAGIQFRL LNRRKGPAVQ GPRAQADRKL YRSAAAKIVA GQDGLSLILG
     EAAELLHERG QVTGLRLADD SELQARQIIL TTGTFLNGLI HIGEISRQAG RWGGSTSVTL
     AASLRPLNLP LGRLKTGTPP RILRQSIDWE SLHQQPGDEE PVMFSYLNTV PEAPQVSCAI
     THTNPDTHRI IRENLARSAM YGGRIDGVGP RYCPSIEDKV VRFADKESHQ IFLEPEGLDS
     DLVYPNGIST SLPEDIQLAY VRSIRGLERA QIAQPGYAVE YDYVDPRALA ASLEVKNLSG
     LFLAGQINGT TGYEEAAAQG LVAGLNAALK AQGREALHFS RSQSYIGVMI DDLTTRGVSE
     PYRMFTSRAE FRLSLRADNA DQRLTPFGID IGCVGQERRA AFSEKMRRYT AARDRAESVS
     FTPTELSRSG IEVRHDGARR SLFALLAQQE IPQDQVLALD DQLVLQDPAI IRQLATDALY
     HQYTDRQGKD AELLRKEEAV AIPAEFDYDA LSGLSNELKF KLNQHRPATL AAAANIEGMT
     PAALTLILAV IRAGNRRSA
//

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