(data stored in ACNUC7421 zone)

SWISSPROT: A1AZA1_PARDP

ID   A1AZA1_PARDP            Unreviewed;       133 AA.
AC   A1AZA1;
DT   23-JAN-2007, integrated into UniProtKB/TrEMBL.
DT   23-JAN-2007, sequence version 1.
DT   08-MAY-2019, entry version 82.
DE   RecName: Full=Ribonuclease VapC {ECO:0000256|HAMAP-Rule:MF_00265};
DE            Short=RNase VapC {ECO:0000256|HAMAP-Rule:MF_00265};
DE            EC=3.1.-.- {ECO:0000256|HAMAP-Rule:MF_00265};
DE   AltName: Full=Toxin VapC {ECO:0000256|HAMAP-Rule:MF_00265};
GN   Name=vapC {ECO:0000256|HAMAP-Rule:MF_00265};
GN   OrderedLocusNames=Pden_0483 {ECO:0000313|EMBL:ABL68595.1};
OS   Paracoccus denitrificans (strain Pd 1222).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
OC   Rhodobacteraceae; Paracoccus.
OX   NCBI_TaxID=318586 {ECO:0000313|EMBL:ABL68595.1, ECO:0000313|Proteomes:UP000000361};
RN   [1] {ECO:0000313|Proteomes:UP000000361}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Pd 1222 {ECO:0000313|Proteomes:UP000000361};
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H.,
RA   Pitluck S., Munk A.C., Brettin T., Bruce D., Han C., Tapia R.,
RA   Gilna P., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Lykidis A., Spiro S., Richardson D.J., Moir J.W.B., Ferguson S.J.,
RA   van Spanning R.J.M., Richardson P.;
RT   "Complete sequence of chromosome 1 of Paracoccus denitrificans
RT   PD1222.";
RL   Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Toxic component of a toxin-antitoxin (TA) system. An
CC       RNase. {ECO:0000256|HAMAP-Rule:MF_00265}.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000256|HAMAP-
CC         Rule:MF_00265, ECO:0000256|SAAS:SAAS00608033};
CC   -!- SIMILARITY: Belongs to the PINc/VapC protein family.
CC       {ECO:0000256|HAMAP-Rule:MF_00265, ECO:0000256|SAAS:SAAS00541436}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; CP000489; ABL68595.1; -; Genomic_DNA.
DR   STRING; 318586.Pden_0483; -.
DR   PRIDE; A1AZA1; -.
DR   EnsemblBacteria; ABL68595; ABL68595; Pden_0483.
DR   KEGG; pde:Pden_0483; -.
DR   eggNOG; ENOG4105M0J; Bacteria.
DR   eggNOG; COG1487; LUCA.
DR   HOGENOM; HOG000121274; -.
DR   KO; K18828; -.
DR   OMA; DTCVISD; -.
DR   Proteomes; UP000000361; Chromosome 1.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0004540; F:ribonuclease activity; IEA:InterPro.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR   HAMAP; MF_00265; VapC_Nob1; 1.
DR   InterPro; IPR029060; PIN-like_dom_sf.
DR   InterPro; IPR002716; PIN_dom.
DR   InterPro; IPR022907; VapC_family.
DR   Pfam; PF01850; PIN; 1.
DR   SMART; SM00670; PINc; 1.
DR   SUPFAM; SSF88723; SSF88723; 1.
PE   3: Inferred from homology;
DR   PRODOM; A1AZA1.
DR   SWISS-2DPAGE; A1AZA1.
KW   Complete proteome {ECO:0000313|Proteomes:UP000000361};
KW   Hydrolase {ECO:0000256|HAMAP-Rule:MF_00265,
KW   ECO:0000256|SAAS:SAAS00423921};
KW   Magnesium {ECO:0000256|HAMAP-Rule:MF_00265,
KW   ECO:0000256|SAAS:SAAS00541414};
KW   Metal-binding {ECO:0000256|HAMAP-Rule:MF_00265,
KW   ECO:0000256|SAAS:SAAS00423897};
KW   Nuclease {ECO:0000256|HAMAP-Rule:MF_00265,
KW   ECO:0000256|SAAS:SAAS00423900};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000361};
KW   Toxin {ECO:0000256|HAMAP-Rule:MF_00265};
KW   Toxin-antitoxin system {ECO:0000256|HAMAP-Rule:MF_00265,
KW   ECO:0000256|SAAS:SAAS00986330}.
FT   DOMAIN        2    121       PINc. {ECO:0000259|SMART:SM00670}.
FT   METAL         7      7       Magnesium. {ECO:0000256|HAMAP-Rule:
FT                                MF_00265}.
FT   METAL        98     98       Magnesium. {ECO:0000256|HAMAP-Rule:
FT                                MF_00265}.
SQ   SEQUENCE   133 AA;  14135 MW;  BC13664272472964 CRC64;
     MTLYMLDTNI VSDLLRHPDG SAAKRIAEVG PDAICVSIIT AAELRYGCAR KGSAKLLAHV
     EAILENVQVL ALDVPADAEY GGIRAELEAA GKPIGPNDLL IAAHAYAAGA ILVTDNTGEF
     SRVRGLRVEN WIR
//

If you have problems or comments...

PBIL Back to PBIL home page