(data stored in ACNUC1104 zone)

SWISSPROT: A1SCV0_NOCSJ

ID   A1SCV0_NOCSJ            Unreviewed;       542 AA.
AC   A1SCV0;
DT   06-FEB-2007, integrated into UniProtKB/TrEMBL.
DT   06-FEB-2007, sequence version 1.
DT   08-MAY-2019, entry version 74.
DE   SubName: Full=Delta-1-pyrroline-5-carboxylate dehydrogenase {ECO:0000313|EMBL:ABL79635.1};
GN   OrderedLocusNames=Noca_0089 {ECO:0000313|EMBL:ABL79635.1};
OS   Nocardioides sp. (strain ATCC BAA-499 / JS614).
OC   Bacteria; Actinobacteria; Propionibacteriales; Nocardioidaceae;
OC   Nocardioides.
OX   NCBI_TaxID=196162 {ECO:0000313|EMBL:ABL79635.1, ECO:0000313|Proteomes:UP000000640};
RN   [1] {ECO:0000313|Proteomes:UP000000640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-499 / JS614 {ECO:0000313|Proteomes:UP000000640};
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H.,
RA   Pitluck S., Thompson L.S., Brettin T., Bruce D., Han C., Tapia R.,
RA   Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E.,
RA   Mattes T., Gossett J., Richardson P.;
RT   "Complete sequence of chromosome 1 of Nocardioides sp. JS614.";
RL   Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ABL79635.1, ECO:0000313|Proteomes:UP000000640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-499 / JS614 {ECO:0000313|Proteomes:UP000000640};
RX   PubMed=21551312; DOI=10.1128/JB.05109-11;
RA   Coleman N.V., Wilson N.L., Barry K., Brettin T.S., Bruce D.C.,
RA   Copeland A., Dalin E., Detter J.C., Del Rio T.G., Goodwin L.A.,
RA   Hammon N.M., Han S., Hauser L.J., Israni S., Kim E., Kyrpides N.,
RA   Land M.L., Lapidus A., Larimer F.W., Lucas S., Pitluck S.,
RA   Richardson P., Schmutz J., Tapia R., Thompson S., Tice H.N.,
RA   Spain J.C., Gossett J.G., Mattes T.E.;
RT   "Genome Sequence of the ethene- and vinyl chloride-oxidizing
RT   actinomycete Nocardioides sp. strain JS614.";
RL   J. Bacteriol. 193:3399-3400(2011).
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DR   EMBL; CP000509; ABL79635.1; -; Genomic_DNA.
DR   RefSeq; WP_011753586.1; NC_008699.1.
DR   STRING; 196162.Noca_0089; -.
DR   EnsemblBacteria; ABL79635; ABL79635; Noca_0089.
DR   KEGG; nca:Noca_0089; -.
DR   eggNOG; ENOG4107RMK; Bacteria.
DR   eggNOG; COG1012; LUCA.
DR   HOGENOM; HOG000271511; -.
DR   KO; K00294; -.
DR   OMA; FAGIHFT; -.
DR   OrthoDB; 744602at2; -.
DR   BioCyc; NSP196162:GH4V-89-MONOMER; -.
DR   Proteomes; UP000000640; Chromosome.
DR   GO; GO:0003842; F:1-pyrroline-5-carboxylate dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   GO; GO:0010133; P:proline catabolic process to glutamate; IEA:InterPro.
DR   CDD; cd07123; ALDH_F4-17_P5CDH; 1.
DR   Gene3D; 3.40.309.10; -; 1.
DR   Gene3D; 3.40.605.10; -; 1.
DR   InterPro; IPR016161; Ald_DH/histidinol_DH.
DR   InterPro; IPR016163; Ald_DH_C.
DR   InterPro; IPR016160; Ald_DH_CS_CYS.
DR   InterPro; IPR016162; Ald_DH_N.
DR   InterPro; IPR015590; Aldehyde_DH_dom.
DR   InterPro; IPR005931; P5CDH/ALDH4A1.
DR   Pfam; PF00171; Aldedh; 1.
DR   SUPFAM; SSF53720; SSF53720; 1.
DR   TIGRFAMs; TIGR01236; D1pyr5carbox1; 1.
DR   PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
PE   4: Predicted;
DR   PRODOM; A1SCV0.
DR   SWISS-2DPAGE; A1SCV0.
KW   Complete proteome {ECO:0000313|Proteomes:UP000000640};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000640}.
FT   DOMAIN       50    524       Aldedh. {ECO:0000259|Pfam:PF00171}.
FT   ACT_SITE    328    328       {ECO:0000256|PROSITE-ProRule:PRU10008}.
SQ   SEQUENCE   542 AA;  58879 MW;  D2B028BD40D9A440 CRC64;
     MDAVTTPPAP TNEPNLTYAP GAPERATLVA EIEKLQKTQK TLHAYIGGRW RAGGGAEIPV
     VQPHDHQHVL GTMKNSTQAD ARAAITAASD AAPQWRDMTF DDRAAVLLKA ADLLAGPWRQ
     RLNAATMLGQ SKTAFQAEID SACELVDFWR FNVHYAKQIL TDQPIANSPG VWNRTDHRPL
     EGFVYAITPF NFTAIAGNLP TAPVLMGNTV LWKPSSTQQL AASLTMELLE EAGMPPGVIN
     MLPGDGLAVS EVALAHPDLA GIHFTGSTPL FQRLWKTVGE NIARYRSYPR LVGETGGKDF
     IVAHASADPD VLRTAMIRGA FEFQGQKCSA ASRAYVARSV WNKMKDSFLS EIESLTVGDP
     TDFSHFMGAV IDDRAFARHR AAIDRAKRSG KLDILAGGTL DDTVGWFVRP TAIESGDPTD
     EIFTTEYFGP ILAVHVFDDG DFEKVVHAME SSTPYALTGS IIARDRRTIA WAQETLRFAA
     GNFYVNDKPT GAVVGQQPFG GGRASGTNDK AGSAANLLRW TSPRSIKETF DPPTDYRYPH
     LG
//

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