(data stored in ACNUC1104 zone)

SWISSPROT: A1SCY4_NOCSJ

ID   A1SCY4_NOCSJ            Unreviewed;       471 AA.
AC   A1SCY4;
DT   06-FEB-2007, integrated into UniProtKB/TrEMBL.
DT   06-FEB-2007, sequence version 1.
DT   08-MAY-2019, entry version 65.
DE   SubName: Full=Drug resistance transporter, EmrB/QacA subfamily {ECO:0000313|EMBL:ABL79669.1};
GN   OrderedLocusNames=Noca_0124 {ECO:0000313|EMBL:ABL79669.1};
OS   Nocardioides sp. (strain ATCC BAA-499 / JS614).
OC   Bacteria; Actinobacteria; Propionibacteriales; Nocardioidaceae;
OC   Nocardioides.
OX   NCBI_TaxID=196162 {ECO:0000313|EMBL:ABL79669.1, ECO:0000313|Proteomes:UP000000640};
RN   [1] {ECO:0000313|Proteomes:UP000000640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-499 / JS614 {ECO:0000313|Proteomes:UP000000640};
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H.,
RA   Pitluck S., Thompson L.S., Brettin T., Bruce D., Han C., Tapia R.,
RA   Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E.,
RA   Mattes T., Gossett J., Richardson P.;
RT   "Complete sequence of chromosome 1 of Nocardioides sp. JS614.";
RL   Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ABL79669.1, ECO:0000313|Proteomes:UP000000640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-499 / JS614 {ECO:0000313|Proteomes:UP000000640};
RX   PubMed=21551312; DOI=10.1128/JB.05109-11;
RA   Coleman N.V., Wilson N.L., Barry K., Brettin T.S., Bruce D.C.,
RA   Copeland A., Dalin E., Detter J.C., Del Rio T.G., Goodwin L.A.,
RA   Hammon N.M., Han S., Hauser L.J., Israni S., Kim E., Kyrpides N.,
RA   Land M.L., Lapidus A., Larimer F.W., Lucas S., Pitluck S.,
RA   Richardson P., Schmutz J., Tapia R., Thompson S., Tice H.N.,
RA   Spain J.C., Gossett J.G., Mattes T.E.;
RT   "Genome Sequence of the ethene- and vinyl chloride-oxidizing
RT   actinomycete Nocardioides sp. strain JS614.";
RL   J. Bacteriol. 193:3399-3400(2011).
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC       {ECO:0000256|SAAS:SAAS00769108}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; CP000509; ABL79669.1; -; Genomic_DNA.
DR   RefSeq; WP_011753620.1; NC_008699.1.
DR   STRING; 196162.Noca_0124; -.
DR   EnsemblBacteria; ABL79669; ABL79669; Noca_0124.
DR   KEGG; nca:Noca_0124; -.
DR   eggNOG; ENOG4105C0R; Bacteria.
DR   eggNOG; ENOG410XNN3; LUCA.
DR   HOGENOM; HOG000239124; -.
DR   OMA; LDIIWRM; -.
DR   OrthoDB; 1108236at2; -.
DR   BioCyc; NSP196162:GH4V-123-MONOMER; -.
DR   Proteomes; UP000000640; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   CDD; cd06174; MFS; 1.
DR   InterPro; IPR004638; EmrB-like.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   TIGRFAMs; TIGR00711; efflux_EmrB; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   3: Inferred from homology;
DR   PRODOM; A1SCY4.
DR   SWISS-2DPAGE; A1SCY4.
KW   Cell membrane {ECO:0000256|SAAS:SAAS00769078};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000640};
KW   Membrane {ECO:0000256|SAAS:SAAS00769060, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000640};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00769091,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00769070,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00769034}.
FT   TRANSMEM     12     30       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     53     71       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     83    102       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    108    129       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    141    163       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    169    191       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    203    223       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    229    246       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    267    291       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    297    317       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    338    358       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    364    388       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    400    420       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    432    454       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       17    460       MFS. {ECO:0000259|PROSITE:PS50850}.
SQ   SEQUENCE   471 AA;  47855 MW;  B081FDE8EF20E976 CRC64;
     MAGPDGVRLG TATGRAVVLA AVLGSGMTML DGTVVNVALR TIGADLDASL PELQWITNGY
     LLSMASLILL GGSLGDRFGR RRVFVVGTVW FAVASLACGS APTPEVLIVA RILQGVGAAL
     LTPGSLAMIQ GAFVRDDRAQ AIGSWSGLTS IAAAVGPLVG GALVQYASWR WIFLVNLPIA
     TLTVVVARRA VPETRDPNAP RRFDALGAVL AALALGGLTY ALIEWGGALA PWAVVVTVLA
     AAAYLVDERR SDHPMLPLGI FADRTFTAAN AMTMVVYAAL GAVLFFLVLQ LQTVSGYGAL
     GAGLATLPIT FCMLLLASQG GRLGARIGPR VPMSLGPLVM AAGTLLLLRV GAGTTYWTDV
     LPGLVVFGLG LALLVAPLTA TVLAAVADEH AGIASGVNNA VARAGSLLAV AALPAAVGLR
     GEEYADPVAF DAAYGSAILA CAALLALGGV VSWLSIRDPG IGRTAAPPIG R
//

If you have problems or comments...

PBIL Back to PBIL home page