(data stored in ACNUC1104 zone)

SWISSPROT: A1SE18_NOCSJ

ID   A1SE18_NOCSJ            Unreviewed;       624 AA.
AC   A1SE18;
DT   06-FEB-2007, integrated into UniProtKB/TrEMBL.
DT   06-FEB-2007, sequence version 1.
DT   08-MAY-2019, entry version 78.
DE   SubName: Full=Sodium/proton antiporter, CPA1 family {ECO:0000313|EMBL:ABL80053.1};
GN   OrderedLocusNames=Noca_0511 {ECO:0000313|EMBL:ABL80053.1};
OS   Nocardioides sp. (strain ATCC BAA-499 / JS614).
OC   Bacteria; Actinobacteria; Propionibacteriales; Nocardioidaceae;
OC   Nocardioides.
OX   NCBI_TaxID=196162 {ECO:0000313|EMBL:ABL80053.1, ECO:0000313|Proteomes:UP000000640};
RN   [1] {ECO:0000313|Proteomes:UP000000640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-499 / JS614 {ECO:0000313|Proteomes:UP000000640};
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H.,
RA   Pitluck S., Thompson L.S., Brettin T., Bruce D., Han C., Tapia R.,
RA   Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E.,
RA   Mattes T., Gossett J., Richardson P.;
RT   "Complete sequence of chromosome 1 of Nocardioides sp. JS614.";
RL   Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ABL80053.1, ECO:0000313|Proteomes:UP000000640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-499 / JS614 {ECO:0000313|Proteomes:UP000000640};
RX   PubMed=21551312; DOI=10.1128/JB.05109-11;
RA   Coleman N.V., Wilson N.L., Barry K., Brettin T.S., Bruce D.C.,
RA   Copeland A., Dalin E., Detter J.C., Del Rio T.G., Goodwin L.A.,
RA   Hammon N.M., Han S., Hauser L.J., Israni S., Kim E., Kyrpides N.,
RA   Land M.L., Lapidus A., Larimer F.W., Lucas S., Pitluck S.,
RA   Richardson P., Schmutz J., Tapia R., Thompson S., Tice H.N.,
RA   Spain J.C., Gossett J.G., Mattes T.E.;
RT   "Genome Sequence of the ethene- and vinyl chloride-oxidizing
RT   actinomycete Nocardioides sp. strain JS614.";
RL   J. Bacteriol. 193:3399-3400(2011).
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DR   EMBL; CP000509; ABL80053.1; -; Genomic_DNA.
DR   STRING; 196162.Noca_0511; -.
DR   EnsemblBacteria; ABL80053; ABL80053; Noca_0511.
DR   KEGG; nca:Noca_0511; -.
DR   eggNOG; ENOG4105EEQ; Bacteria.
DR   eggNOG; COG0025; LUCA.
DR   HOGENOM; HOG000263348; -.
DR   KO; K03316; -.
DR   OMA; RRIDDEM; -.
DR   BioCyc; NSP196162:GH4V-515-MONOMER; -.
DR   Proteomes; UP000000640; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015299; F:solute:proton antiporter activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   Gene3D; 3.30.40.10; -; 1.
DR   InterPro; IPR006153; Cation/H_exchanger.
DR   InterPro; IPR018422; Cation/H_exchanger_CPA1.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   InterPro; IPR001607; Znf_UBP.
DR   PANTHER; PTHR10110; PTHR10110; 1.
DR   Pfam; PF00999; Na_H_Exchanger; 1.
DR   Pfam; PF02148; zf-UBP; 1.
DR   PROSITE; PS50271; ZF_UBP; 1.
PE   4: Predicted;
DR   PRODOM; A1SE18.
DR   SWISS-2DPAGE; A1SE18.
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000640};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000640};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM      6     24       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     60     79       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     86    106       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    184    204       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    268    291       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    303    325       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    345    368       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    377    400       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      558    624       UBP-type. {ECO:0000259|PROSITE:PS50271}.
FT   COILED      416    436       {ECO:0000256|SAM:Coils}.
FT   COILED      512    532       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   624 AA;  67546 MW;  CB514C9A0A04915D CRC64;
     MADVDTALFL VALAVAVLAG VVVAGRIGVP APLLLVVAGV AASFLPFLPE VHLEPDVVLF
     GLLPPLLYSA AITSSLVDFN ANRRPILLLS VGLVVFTTLG VGVLVHELVP GLSWPVAFAL
     GAVVAPPDAV AATSIGRHIG LPRRVVTILE GESLFNDATA LVSLQTALGA TLVGVELWRV
     GLDFVVAAGG GVLIGVVVFL VVGAMRRRLS DPMLDVAMSF VIPFTAFLAA EEVHASGVVA
     VVTAGLLLGH RAPVLQTAQS RIAERINWRT IAFLLENTVF ALIGLQARWL FDDLGESTLS
     PARIIAVSAA TLVAVIVLRL VWVFLSRSLL VRPRVDPATG QVPPWSFTLL LGWSGMRGVV
     TLAAAFLIPP DTRHREVLLV VAFAVVAGTL LVQGLSLPWL TRRLHVPAPD PLDDALARAT
     LLQQASKAAV EELERQEYDD QAGVGDLIRQ RLDQRNFAAW ERLGTTADQE SPAAVYYRIR
     MAMIAAERRR ILEIRRSGTV ASEVIAEVLS MLDVEESMLD NAHQERDEAE DYARRRWTLG
     ETCDDLGRYP VVDAEPATYC QACLDEGTRW VALRRCLECG NLACCDSSPR QHATAHFRET
     QHPVMQSAEP GEDWRWCYLH HLTA
//

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