(data stored in ACNUC7421 zone)

SWISSPROT: CH601_POLNA

ID   CH601_POLNA             Reviewed;         544 AA.
AC   A1VJ84;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   06-FEB-2007, sequence version 1.
DT   11-DEC-2019, entry version 72.
DE   RecName: Full=60 kDa chaperonin 1 {ECO:0000255|HAMAP-Rule:MF_00600};
DE   AltName: Full=GroEL protein 1 {ECO:0000255|HAMAP-Rule:MF_00600};
DE   AltName: Full=Protein Cpn60 1 {ECO:0000255|HAMAP-Rule:MF_00600};
GN   Name=groL1 {ECO:0000255|HAMAP-Rule:MF_00600};
GN   Synonyms=groEL1 {ECO:0000255|HAMAP-Rule:MF_00600};
GN   OrderedLocusNames=Pnap_0389;
OS   Polaromonas naphthalenivorans (strain CJ2).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Comamonadaceae; Polaromonas.
OX   NCBI_TaxID=365044;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CJ2;
RX   PubMed=19453698; DOI=10.1111/j.1462-2920.2009.01947.x;
RA   Yagi J.M., Sims D., Brettin T., Bruce D., Madsen E.L.;
RT   "The genome of Polaromonas naphthalenivorans strain CJ2, isolated from coal
RT   tar-contaminated sediment, reveals physiological and metabolic versatility
RT   and evolution through extensive horizontal gene transfer.";
RL   Environ. Microbiol. 11:2253-2270(2009).
CC   -!- FUNCTION: Prevents misfolding and promotes the refolding and proper
CC       assembly of unfolded polypeptides generated under stress conditions.
CC       {ECO:0000255|HAMAP-Rule:MF_00600}.
CC   -!- SUBUNIT: Oligomer of 14 subunits composed of two stacked rings of 7
CC       subunits. {ECO:0000255|HAMAP-Rule:MF_00600}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00600}.
CC   -!- SIMILARITY: Belongs to the chaperonin (HSP60) family.
CC       {ECO:0000255|HAMAP-Rule:MF_00600}.
DR   EMBL; CP000529; ABM35712.1; -; Genomic_DNA.
DR   RefSeq; WP_011799815.1; NC_008781.1.
DR   SMR; A1VJ84; -.
DR   STRING; 365044.Pnap_0389; -.
DR   PRIDE; A1VJ84; -.
DR   EnsemblBacteria; ABM35712; ABM35712; Pnap_0389.
DR   KEGG; pna:Pnap_0389; -.
DR   eggNOG; COG0459; LUCA.
DR   HOGENOM; HOG000076290; -.
DR   OMA; IGKVGPD; -.
DR   OrthoDB; 265347at2; -.
DR   Proteomes; UP000000644; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0042026; P:protein refolding; IEA:UniProtKB-UniRule.
DR   CDD; cd03344; GroEL; 1.
DR   Gene3D; 1.10.560.10; -; 1.
DR   Gene3D; 3.30.260.10; -; 1.
DR   Gene3D; 3.50.7.10; -; 1.
DR   HAMAP; MF_00600; CH60; 1.
DR   InterPro; IPR018370; Chaperonin_Cpn60_CS.
DR   InterPro; IPR001844; Chaprnin_Cpn60.
DR   InterPro; IPR002423; Cpn60/TCP-1.
DR   InterPro; IPR027409; GroEL-like_apical_dom_sf.
DR   InterPro; IPR027413; GROEL-like_equatorial_sf.
DR   InterPro; IPR027410; TCP-1-like_intermed_sf.
DR   Pfam; PF00118; Cpn60_TCP1; 1.
DR   PRINTS; PR00298; CHAPERONIN60.
DR   SUPFAM; SSF48592; SSF48592; 1.
DR   SUPFAM; SSF52029; SSF52029; 1.
DR   SUPFAM; SSF54849; SSF54849; 1.
DR   TIGRFAMs; TIGR02348; GroEL; 1.
DR   PROSITE; PS00296; CHAPERONINS_CPN60; 1.
PE   3: Inferred from homology;
DR   PRODOM; A1VJ84.
DR   SWISS-2DPAGE; A1VJ84.
KW   ATP-binding; Chaperone; Cytoplasm; Nucleotide-binding; Reference proteome.
FT   CHAIN           1..544
FT                   /note="60 kDa chaperonin 1"
FT                   /id="PRO_0000332036"
SQ   SEQUENCE   544 AA;  57763 MW;  19D0B172544E399B CRC64;
     MKPKQLIFHD AARGKIWRGV EALAEAVKVT LGPRGRTVIL ERDFGPPQIV NSGVLVAKSI
     ELEDRFENMG AQLLREVAAR TSEMAGDGTT TATVLAHGMI QEGLRYLAGG MNPMDLKRGI
     ELAIDTVVAE LQRMAKPCAS SQEIAHVAAI SANNDRSIGD LLASAIDKVG REGAISIEDG
     SGLVSVLEVV EGMQFDRGFL SPYFINNAER QSAVLEDVSI LLCEGRLTSL NDLLPLLEEV
     VKAGRPLLVI AEDVDSDSLA ALVINTMRGT LKTCAVKAPG FGDRRKAMVQ DIAVLTGGTV
     VSDEVGLTLG KVRLQDLGRA TRAEITKEST TLIGGAGKPQ AIRDRIATIR KERELAASDY
     DREKLDERAA KLSGGVALIK VGAATETELK ERKLRVEDAL HATRAAVEEG IVPGGGVALL
     RARRTLAGLT GGTLDETSGI RLVSRALEEP LRRIVSNAGD EPSVILNRVD ESPDPAFGYN
     AATRAYGDLL QMGVIDPAKV TRLALQNAAS IASLILTTDC MIATAPKPSS EEGALNPEGS
     SPMF
//

If you have problems or comments...

PBIL Back to PBIL home page