(data stored in ACNUC7421 zone)

SWISSPROT: A5FTK6_ACICJ

ID   A5FTK6_ACICJ            Unreviewed;       206 AA.
AC   A5FTK6;
DT   12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT   12-JUN-2007, sequence version 1.
DT   07-JUN-2017, entry version 63.
DE   RecName: Full=Holliday junction ATP-dependent DNA helicase RuvA {ECO:0000256|HAMAP-Rule:MF_00031};
DE            EC=3.6.4.12 {ECO:0000256|HAMAP-Rule:MF_00031};
GN   Name=ruvA {ECO:0000256|HAMAP-Rule:MF_00031};
GN   OrderedLocusNames=Acry_3326 {ECO:0000313|EMBL:ABQ28938.1};
OS   Acidiphilium cryptum (strain JF-5).
OG   Plasmid pACRY02 {ECO:0000313|EMBL:ABQ28938.1,
OG   ECO:0000313|Proteomes:UP000000245}.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodospirillales;
OC   Acetobacteraceae; Acidiphilium.
OX   NCBI_TaxID=349163 {ECO:0000313|EMBL:ABQ28938.1, ECO:0000313|Proteomes:UP000000245};
RN   [1] {ECO:0000313|EMBL:ABQ28938.1, ECO:0000313|Proteomes:UP000000245}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JF-5 {ECO:0000313|EMBL:ABQ28938.1,
RC   ECO:0000313|Proteomes:UP000000245};
RC   PLASMID=Plasmid pACRY02 {ECO:0000313|Proteomes:UP000000245};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H.,
RA   Pitluck S., Sims D., Brettin T., Bruce D., Han C., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Magnuson T.,
RA   Richardson P.;
RT   "Complete sequence of plasmid2 pACRY02 of Acidiphilium cryptum JF-5.";
RL   Submitted (MAY-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: The RuvA-RuvB complex in the presence of ATP renatures
CC       cruciform structure in supercoiled DNA with palindromic sequence,
CC       indicating that it may promote strand exchange reactions in
CC       homologous recombination. RuvAB is a helicase that mediates the
CC       Holliday junction migration by localized denaturation and
CC       reannealing. RuvA stimulates, in the presence of DNA, the weak
CC       ATPase activity of RuvB. {ECO:0000256|HAMAP-Rule:MF_00031}.
CC   -!- CATALYTIC ACTIVITY: ATP + H(2)O = ADP + phosphate.
CC       {ECO:0000256|HAMAP-Rule:MF_00031}.
CC   -!- SUBUNIT: Forms a complex with RuvB. {ECO:0000256|HAMAP-
CC       Rule:MF_00031}.
CC   -!- SIMILARITY: Belongs to the RuvA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00031}.
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DR   EMBL; CP000690; ABQ28938.1; -; Genomic_DNA.
DR   RefSeq; WP_011930715.1; NC_009468.1.
DR   ProteinModelPortal; A5FTK6; -.
DR   EnsemblBacteria; ABQ28938; ABQ28938; Acry_3326.
DR   KEGG; acr:Acry_3326; -.
DR   HOGENOM; HOG000057115; -.
DR   OrthoDB; POG091H02EF; -.
DR   Proteomes; UP000000245; Plasmid pACRY02.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0009378; F:four-way junction helicase activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-HAMAP.
DR   GO; GO:0009432; P:SOS response; IEA:UniProtKB-HAMAP.
DR   HAMAP; MF_00031; DNA_helic_RuvA; 1.
DR   InterPro; IPR013849; DNA_helicase_Holl-junc_RuvA_I.
DR   InterPro; IPR003583; Hlx-hairpin-Hlx_DNA-bd_motif.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR000085; RuvA.
DR   InterPro; IPR010994; RuvA_2-like.
DR   PANTHER; PTHR33796; PTHR33796; 1.
DR   Pfam; PF01330; RuvA_N; 1.
DR   SMART; SM00278; HhH1; 2.
DR   SUPFAM; SSF47781; SSF47781; 1.
DR   SUPFAM; SSF50249; SSF50249; 1.
PE   3: Inferred from homology;
DR   PRODOM; A5FTK6.
DR   SWISS-2DPAGE; A5FTK6.
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00031};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000245};
KW   DNA damage {ECO:0000256|HAMAP-Rule:MF_00031};
KW   DNA recombination {ECO:0000256|HAMAP-Rule:MF_00031};
KW   DNA repair {ECO:0000256|HAMAP-Rule:MF_00031};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00031};
KW   Helicase {ECO:0000256|HAMAP-Rule:MF_00031,
KW   ECO:0000313|EMBL:ABQ28938.1};
KW   Hydrolase {ECO:0000256|HAMAP-Rule:MF_00031};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00031};
KW   Plasmid {ECO:0000313|EMBL:ABQ28938.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000245};
KW   SOS response {ECO:0000256|HAMAP-Rule:MF_00031}.
FT   DOMAIN       73     92       HhH1. {ECO:0000259|SMART:SM00278}.
FT   DOMAIN      108    127       HhH1. {ECO:0000259|SMART:SM00278}.
SQ   SEQUENCE   206 AA;  21305 MW;  B105F4CE26AC95AA CRC64;
     MITQLTGIPR RIGDQECVID VHGVGYGVHV PSATLDMIEG EAGPVTILIQ TRMSDSEISL
     YGFATPADLQ TFRKLVGVQG VGPATALNLL SQLAPEELWR AIREADQKAL TAVKGIGPAA
     AKRLISELES HAAKLAAEMP APAARLDLGL SADQLAQSLQ RLGHAPSAAR AAAQFALNGA
     KPGDTEQELV ARALQAAAGM TTGAAA
//

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