(data stored in ACNUC7421 zone)

SWISSPROT: YIDC_SHESH

ID   YIDC_SHESH              Reviewed;         544 AA.
AC   A8FP42;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   13-NOV-2007, sequence version 1.
DT   30-AUG-2017, entry version 59.
DE   RecName: Full=Membrane protein insertase YidC {ECO:0000255|HAMAP-Rule:MF_01810};
DE   AltName: Full=Foldase YidC {ECO:0000255|HAMAP-Rule:MF_01810};
DE   AltName: Full=Membrane integrase YidC {ECO:0000255|HAMAP-Rule:MF_01810};
DE   AltName: Full=Membrane protein YidC {ECO:0000255|HAMAP-Rule:MF_01810};
GN   Name=yidC {ECO:0000255|HAMAP-Rule:MF_01810};
GN   OrderedLocusNames=Ssed_0002;
OS   Shewanella sediminis (strain HAW-EB3).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC   Shewanellaceae; Shewanella.
OX   NCBI_TaxID=425104;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HAW-EB3;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T.,
RA   Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D.,
RA   Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L.,
RA   Kyrpides N., Kim E., Zhao J.-S., Richardson P.;
RT   "Complete sequence of Shewanella sediminis HAW-EB3.";
RL   Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for the insertion and/or proper folding and/or
CC       complex formation of integral membrane proteins into the membrane.
CC       Involved in integration of membrane proteins that insert both
CC       dependently and independently of the Sec translocase complex, as
CC       well as at least some lipoproteins. Aids folding of multispanning
CC       membrane proteins. {ECO:0000255|HAMAP-Rule:MF_01810}.
CC   -!- SUBUNIT: Interacts with the Sec translocase complex via SecD.
CC       Specifically interacts with transmembrane segments of nascent
CC       integral membrane proteins during membrane integration.
CC       {ECO:0000255|HAMAP-Rule:MF_01810}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01810}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01810}.
CC   -!- SIMILARITY: Belongs to the OXA1/ALB3/YidC family. Type 1
CC       subfamily. {ECO:0000255|HAMAP-Rule:MF_01810}.
DR   EMBL; CP000821; ABV34615.1; -; Genomic_DNA.
DR   RefSeq; WP_012004142.1; NC_009831.1.
DR   ProteinModelPortal; A8FP42; -.
DR   SMR; A8FP42; -.
DR   STRING; 425104.Ssed_0002; -.
DR   EnsemblBacteria; ABV34615; ABV34615; Ssed_0002.
DR   KEGG; sse:Ssed_0002; -.
DR   eggNOG; ENOG4105DHW; Bacteria.
DR   eggNOG; COG0706; LUCA.
DR   HOGENOM; HOG000101822; -.
DR   KO; K03217; -.
DR   OMA; INPVAGC; -.
DR   OrthoDB; POG091H00BE; -.
DR   Proteomes; UP000002015; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0051205; P:protein insertion into membrane; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   HAMAP; MF_01810; YidC_type1; 1.
DR   InterPro; IPR019998; Membr_insert_YidC.
DR   InterPro; IPR028055; Membr_insert_YidC/Oxa1_C.
DR   InterPro; IPR028053; Membr_insert_YidC_N.
DR   InterPro; IPR001708; Membrane_insert_OXA1/ALB3/YidC.
DR   PANTHER; PTHR12428; PTHR12428; 1.
DR   Pfam; PF02096; 60KD_IMP; 1.
DR   Pfam; PF14849; YidC_periplas; 1.
DR   PRINTS; PR00701; 60KDINNERMP.
DR   PRINTS; PR01900; YIDCPROTEIN.
DR   TIGRFAMs; TIGR03593; yidC_nterm; 1.
DR   TIGRFAMs; TIGR03592; yidC_oxa1_cterm; 1.
PE   3: Inferred from homology;
DR   PRODOM; A8FP42.
DR   SWISS-2DPAGE; A8FP42.
KW   Cell inner membrane; Cell membrane; Chaperone; Complete proteome;
KW   Membrane; Protein transport; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN         1    544       Membrane protein insertase YidC.
FT                                /FTId=PRO_1000088266.
FT   TRANSMEM      6     26       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01810}.
FT   TRANSMEM    345    365       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01810}.
FT   TRANSMEM    423    443       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01810}.
FT   TRANSMEM    460    480       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01810}.
FT   TRANSMEM    503    523       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01810}.
SQ   SEQUENCE   544 AA;  61116 MW;  6196970F43A7718D CRC64;
     MESQRNILLI GLLFVSFLLW QQWQTDQAPQ PVAMESSSTI PSSSTSDSHS SDVPDADSAL
     PAAVVASKEL ITVNTDQLII KINPIGGDIV YSALVEHKLE LDKDEPFVLL EQTKDINYIA
     QSGLIGRNGI DSSSKGRAHF DSASREYTLA SGQDTLEVPL TFVADNGATY TKMFVFHRGQ
     FKVDVDYVID NSTDQQLQVQ MYGQIKHSIK QSESSMMMPT YRGAAFSTAN TRYEKYSFDD
     MADKNLDEKT LGGWAAMLQH YFVSAWVPPA NDQNIIFSSI SAGGQANIGF RGAVYDVAPG
     ATQTINSEFY VGPKNQEALS AISESLNLVV DYGFLWWLAV PIYKLLMFFQ SLVTNWGLAI
     ILITLTVRGM LYPLTKAQYT SMAKMRNLQP KLAEMKERFG DDRQKMGQAM MELYKKEKVN
     PMGGCLPILL QMPIFIALYW VLLESVELRH APFMLWITDL SVQDPYYVMP ILMGISMFVM
     QKMQPMAPTM DPMQQKMMQW MPVVFTVFFL WFPAGLVLYW LVGNLVAITQ QKIIYAGLAK
     KGLK
//

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