(data stored in ACNUC7421 zone)

SWISSPROT: DNAA_SHESH

ID   DNAA_SHESH              Reviewed;         462 AA.
AC   A8FP46;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   13-NOV-2007, sequence version 1.
DT   07-JUN-2017, entry version 66.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   Name=dnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   OrderedLocusNames=Ssed_0006;
OS   Shewanella sediminis (strain HAW-EB3).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC   Shewanellaceae; Shewanella.
OX   NCBI_TaxID=425104;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HAW-EB3;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T.,
RA   Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D.,
RA   Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L.,
RA   Kyrpides N., Kim E., Zhao J.-S., Richardson P.;
RT   "Complete sequence of Shewanella sediminis HAW-EB3.";
RL   Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00377}.
DR   EMBL; CP000821; ABV34619.1; -; Genomic_DNA.
DR   RefSeq; WP_012004145.1; NC_009831.1.
DR   ProteinModelPortal; A8FP46; -.
DR   SMR; A8FP46; -.
DR   STRING; 425104.Ssed_0006; -.
DR   EnsemblBacteria; ABV34619; ABV34619; Ssed_0006.
DR   KEGG; sse:Ssed_0006; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   HOGENOM; HOG000235659; -.
DR   KO; K02313; -.
DR   OMA; REFNPLF; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000002015; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
DR   PRODOM; A8FP46.
DR   SWISS-2DPAGE; A8FP46.
KW   ATP-binding; Complete proteome; Cytoplasm; DNA replication;
KW   DNA-binding; Nucleotide-binding.
FT   CHAIN         1    462       Chromosomal replication initiator protein
FT                                DnaA.
FT                                /FTId=PRO_1000079964.
FT   NP_BIND     167    174       ATP. {ECO:0000255|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   462 AA;  52422 MW;  412D1AAB2B7E8761 CRC64;
     MAVSLWQQCI GRLQDELSAQ QFSMWIRPLQ AQMDGDTLVL YAPNRFVLDW VRDKYINIIN
     QFFTEQMGSD APKLRFDIGS RPSAPRPVQA TAAVERPKFE QNTKPAKTSF NVNSPEPAMA
     ANHRSNINRT YQFENFVEGK SNQLGKAAAM QVAENPGGAY NPLFLYGGTG LGKTHLLHAV
     GNGIIKNNPN AKVVYMHSER FVQDMVKALQ NNAIEEFKRY YRSVDALFID DIQFFANKDR
     SQEEFFHTFN ALLEGNHQII LTSDKYPKEI DGVEDRLKSR FGWGLTVAIE PPELETRVAI
     LMRKAQESGI NLPDEVAFFI AKRLRSNVRE LEGALNRVIA NANFTGRPIT IDFVREALRD
     LLALQEKLVT IDNIQKTVAE YYKIKMADML SKRRSRSVAR PRQVAMALSK ELTNHSLPEI
     GDAFGGRDHT TVLHACRKIA QLREESHDTK EDYANLIRTL SS
//

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