(data stored in ACNUC7421 zone)

SWISSPROT: A8FPE5_SHESH

ID   A8FPE5_SHESH            Unreviewed;       240 AA.
AC   A8FPE5;
DT   13-NOV-2007, integrated into UniProtKB/TrEMBL.
DT   13-NOV-2007, sequence version 1.
DT   07-JUN-2017, entry version 63.
DE   RecName: Full=3-deoxy-D-manno-octulosonic acid kinase {ECO:0000256|HAMAP-Rule:MF_00521};
DE            Short=Kdo kinase {ECO:0000256|HAMAP-Rule:MF_00521};
DE            EC=2.7.1.166 {ECO:0000256|HAMAP-Rule:MF_00521};
GN   Name=kdkA {ECO:0000256|HAMAP-Rule:MF_00521};
GN   OrderedLocusNames=Ssed_0105 {ECO:0000313|EMBL:ABV34718.1};
OS   Shewanella sediminis (strain HAW-EB3).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC   Shewanellaceae; Shewanella.
OX   NCBI_TaxID=425104 {ECO:0000313|EMBL:ABV34718.1, ECO:0000313|Proteomes:UP000002015};
RN   [1] {ECO:0000313|EMBL:ABV34718.1, ECO:0000313|Proteomes:UP000002015}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HAW-EB3 {ECO:0000313|EMBL:ABV34718.1,
RC   ECO:0000313|Proteomes:UP000002015};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T.,
RA   Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D.,
RA   Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L.,
RA   Kyrpides N., Kim E., Zhao J.-S., Richardson P.;
RT   "Complete sequence of Shewanella sediminis HAW-EB3.";
RL   Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Catalyzes the ATP-dependent phosphorylation of the 3-
CC       deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at
CC       the 4-OH position. {ECO:0000256|HAMAP-Rule:MF_00521}.
CC   -!- CATALYTIC ACTIVITY: Alpha-Kdo-(2->6)-lipid IV(A) + ATP = 4-O-
CC       phospho-alpha-Kdo-(2->6)-lipid IV(A) + ADP. {ECO:0000256|HAMAP-
CC       Rule:MF_00521}.
CC   -!- PATHWAY: Bacterial outer membrane biogenesis; LPS core
CC       biosynthesis. {ECO:0000256|HAMAP-Rule:MF_00521}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000256|HAMAP-
CC       Rule:MF_00521}; Peripheral membrane protein {ECO:0000256|HAMAP-
CC       Rule:MF_00521}; Cytoplasmic side {ECO:0000256|HAMAP-
CC       Rule:MF_00521}.
CC   -!- SIMILARITY: Belongs to the protein kinase superfamily. KdkA/RfaP
CC       family. {ECO:0000256|HAMAP-Rule:MF_00521}.
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DR   EMBL; CP000821; ABV34718.1; -; Genomic_DNA.
DR   RefSeq; WP_012004244.1; NC_009831.1.
DR   ProteinModelPortal; A8FPE5; -.
DR   STRING; 425104.Ssed_0105; -.
DR   EnsemblBacteria; ABV34718; ABV34718; Ssed_0105.
DR   KEGG; sse:Ssed_0105; -.
DR   eggNOG; ENOG4108W7E; Bacteria.
DR   eggNOG; COG0515; LUCA.
DR   HOGENOM; HOG000269423; -.
DR   KO; K11211; -.
DR   OMA; HTDLNAH; -.
DR   OrthoDB; POG091H0606; -.
DR   UniPathway; UPA00958; -.
DR   Proteomes; UP000002015; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:UniProtKB-HAMAP.
DR   GO; GO:0009244; P:lipopolysaccharide core region biosynthetic process; IEA:UniProtKB-UniPathway.
DR   HAMAP; MF_00521; KDO_kinase; 1.
DR   InterPro; IPR022826; KDO_kinase.
DR   InterPro; IPR011009; Kinase-like_dom.
DR   InterPro; IPR010440; LipoPS_kinase.
DR   Pfam; PF06293; Kdo; 1.
DR   SUPFAM; SSF56112; SSF56112; 1.
PE   3: Inferred from homology;
DR   PRODOM; A8FPE5.
DR   SWISS-2DPAGE; A8FPE5.
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00521};
KW   Cell inner membrane {ECO:0000256|HAMAP-Rule:MF_00521};
KW   Cell membrane {ECO:0000256|HAMAP-Rule:MF_00521};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002015};
KW   Kinase {ECO:0000256|HAMAP-Rule:MF_00521, ECO:0000313|EMBL:ABV34718.1};
KW   Lipopolysaccharide biosynthesis {ECO:0000256|HAMAP-Rule:MF_00521};
KW   Membrane {ECO:0000256|HAMAP-Rule:MF_00521};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00521};
KW   Transferase {ECO:0000256|HAMAP-Rule:MF_00521}.
FT   ACT_SITE    171    171       {ECO:0000256|HAMAP-Rule:MF_00521}.
SQ   SEQUENCE   240 AA;  27542 MW;  78800AB1D0C5B0B2 CRC64;
     MQIKQTSSGA IAYCDATPET ISVPWFTFDY WQSQGAITGS SKGRYTTWFV KPNMAETDKS
     EWVLRHYYRG GLMEKISKDS YFYTGLKNTR AVAELSLLEL LYSEGFEVPR PIAANVERNG
     LYYRADIIIE RVEGAQDLVA QLSKSPMSDL QWQQLGACIA KFHQRGVYHA DLNAKNILIT
     PDKFYLIDFD RGEIRTPNPK WQGANLERLL RSFRKELAKL PTLAFNETNW QSLMQGYSNP
//

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