(data stored in ACNUC7421 zone)

SWISSPROT: NFUA_SHESH

ID   NFUA_SHESH              Reviewed;         192 AA.
AC   A8FPL9;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   13-NOV-2007, sequence version 1.
DT   05-JUL-2017, entry version 61.
DE   RecName: Full=Fe/S biogenesis protein NfuA {ECO:0000255|HAMAP-Rule:MF_01637};
GN   Name=nfuA {ECO:0000255|HAMAP-Rule:MF_01637};
GN   OrderedLocusNames=Ssed_0179;
OS   Shewanella sediminis (strain HAW-EB3).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC   Shewanellaceae; Shewanella.
OX   NCBI_TaxID=425104;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HAW-EB3;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T.,
RA   Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D.,
RA   Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L.,
RA   Kyrpides N., Kim E., Zhao J.-S., Richardson P.;
RT   "Complete sequence of Shewanella sediminis HAW-EB3.";
RL   Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-
CC       4S cluster, can transfer this cluster to apoproteins, and thereby
CC       intervenes in the maturation of Fe/S proteins. Could also act as a
CC       scaffold/chaperone for damaged Fe/S proteins. {ECO:0000255|HAMAP-
CC       Rule:MF_01637}.
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01637};
CC       Note=Binds 1 [4Fe-4S] cluster per subunit. The cluster is
CC       presumably bound at the interface of two monomers.
CC       {ECO:0000255|HAMAP-Rule:MF_01637};
CC   -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_01637}.
CC   -!- SIMILARITY: Belongs to the NfuA family. {ECO:0000255|HAMAP-
CC       Rule:MF_01637}.
DR   EMBL; CP000821; ABV34792.1; -; Genomic_DNA.
DR   RefSeq; WP_012004318.1; NC_009831.1.
DR   ProteinModelPortal; A8FPL9; -.
DR   SMR; A8FPL9; -.
DR   STRING; 425104.Ssed_0179; -.
DR   EnsemblBacteria; ABV34792; ABV34792; Ssed_0179.
DR   KEGG; sse:Ssed_0179; -.
DR   eggNOG; ENOG4107RUK; Bacteria.
DR   eggNOG; COG0316; LUCA.
DR   eggNOG; COG0694; LUCA.
DR   HOGENOM; HOG000137052; -.
DR   KO; K07400; -.
DR   OMA; ETCLAYC; -.
DR   OrthoDB; POG091H02LB; -.
DR   Proteomes; UP000002015; Chromosome.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0016226; P:iron-sulfur cluster assembly; IEA:InterPro.
DR   GO; GO:0051604; P:protein maturation; IEA:InterPro.
DR   Gene3D; 2.60.300.12; -; 1.
DR   Gene3D; 3.30.300.130; -; 1.
DR   HAMAP; MF_01637; Fe_S_biogen_NfuA; 1.
DR   InterPro; IPR017726; Fe/S_biogenesis_protein_NfuA.
DR   InterPro; IPR000361; FeS_biogenesis.
DR   InterPro; IPR034904; FSCA_dom.
DR   InterPro; IPR001075; NIF_FeS_clus_asmbl_NifU_C.
DR   PANTHER; PTHR10072:SF59; PTHR10072:SF59; 1.
DR   Pfam; PF01521; Fe-S_biosyn; 1.
DR   Pfam; PF01106; NifU; 1.
DR   ProDom; PD002830; NIF_FeS_clus_asmbl_NifU_C; 1.
DR   SUPFAM; SSF117916; SSF117916; 1.
DR   SUPFAM; SSF89360; SSF89360; 1.
DR   TIGRFAMs; TIGR03341; YhgI_GntY; 1.
PE   3: Inferred from homology;
DR   PRODOM; A8FPL9.
DR   SWISS-2DPAGE; A8FPL9.
KW   4Fe-4S; Complete proteome; Iron; Iron-sulfur; Metal-binding.
FT   CHAIN         1    192       Fe/S biogenesis protein NfuA.
FT                                /FTId=PRO_1000088202.
FT   METAL       149    149       Iron-sulfur (4Fe-4S). {ECO:0000255|HAMAP-
FT                                Rule:MF_01637}.
FT   METAL       152    152       Iron-sulfur (4Fe-4S). {ECO:0000255|HAMAP-
FT                                Rule:MF_01637}.
SQ   SEQUENCE   192 AA;  20663 MW;  B5A45EAA7AFA0F67 CRC64;
     MITISDAAQA HFVTLLADQP EGTHIRVFVI SPGTATAECG VSYCPPDAVE ADDMEFEFNG
     FNAMVDEKSA PFLEEASIDF VTDQLGSQLT LKAPNAKMRK VASDAPLSER IDYVIQSEIN
     PQLASHGGNI MLVEVTEEGT AILQFGGGCN GCSMVDVTLK DGIETQLLEK FPGELTGVKD
     VTEHQHGDHS YQ
//

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