(data stored in ACNUC7421 zone)

SWISSPROT: A8FPQ8_SHESH

ID   A8FPQ8_SHESH            Unreviewed;       193 AA.
AC   A8FPQ8;
DT   13-NOV-2007, integrated into UniProtKB/TrEMBL.
DT   13-NOV-2007, sequence version 1.
DT   08-MAY-2019, entry version 64.
DE   RecName: Full=Ribosomal RNA small subunit methyltransferase D {ECO:0000256|PIRNR:PIRNR004553};
DE            EC=2.1.1.171 {ECO:0000256|PIRNR:PIRNR004553};
GN   OrderedLocusNames=Ssed_0218 {ECO:0000313|EMBL:ABV34831.1};
OS   Shewanella sediminis (strain HAW-EB3).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC   Shewanellaceae; Shewanella.
OX   NCBI_TaxID=425104 {ECO:0000313|EMBL:ABV34831.1, ECO:0000313|Proteomes:UP000002015};
RN   [1] {ECO:0000313|EMBL:ABV34831.1, ECO:0000313|Proteomes:UP000002015}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HAW-EB3 {ECO:0000313|EMBL:ABV34831.1,
RC   ECO:0000313|Proteomes:UP000002015};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T.,
RA   Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D.,
RA   Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L.,
RA   Kyrpides N., Kim E., Zhao J.-S., Richardson P.;
RT   "Complete sequence of Shewanella sediminis HAW-EB3.";
RL   Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Specifically methylates the guanine in position 966 of
CC       16S rRNA in the assembled 30S particle.
CC       {ECO:0000256|PIRNR:PIRNR004553}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=guanosine(966) in 16S rRNA + S-adenosyl-L-methionine =
CC         H(+) + N(2)-methylguanosine(966) in 16S rRNA + S-adenosyl-L-
CC         homocysteine; Xref=Rhea:RHEA:23548, Rhea:RHEA-COMP:10211,
CC         Rhea:RHEA-COMP:10212, ChEBI:CHEBI:15378, ChEBI:CHEBI:57856,
CC         ChEBI:CHEBI:59789, ChEBI:CHEBI:74269, ChEBI:CHEBI:74481;
CC         EC=2.1.1.171; Evidence={ECO:0000256|PIRNR:PIRNR004553};
CC   -!- SIMILARITY: Belongs to the methyltransferase superfamily. RsmD
CC       family. {ECO:0000256|PIRNR:PIRNR004553}.
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DR   EMBL; CP000821; ABV34831.1; -; Genomic_DNA.
DR   RefSeq; WP_012004357.1; NC_009831.1.
DR   STRING; 425104.Ssed_0218; -.
DR   EnsemblBacteria; ABV34831; ABV34831; Ssed_0218.
DR   KEGG; sse:Ssed_0218; -.
DR   eggNOG; ENOG4106H78; Bacteria.
DR   eggNOG; COG0742; LUCA.
DR   HOGENOM; HOG000050676; -.
DR   KO; K08316; -.
DR   OMA; MGAEALC; -.
DR   OrthoDB; 1827334at2; -.
DR   BioCyc; SSED425104:G1G9Y-227-MONOMER; -.
DR   Proteomes; UP000002015; Chromosome.
DR   GO; GO:0052913; F:16S rRNA (guanine(966)-N(2))-methyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR   InterPro; IPR004398; RNA_MeTrfase_RsmD.
DR   InterPro; IPR029063; SAM-dependent_MTases.
DR   PIRSF; PIRSF004553; CHP00095; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   TIGRFAMs; TIGR00095; TIGR00095; 1.
DR   PROSITE; PS00092; N6_MTASE; 1.
PE   3: Inferred from homology;
DR   PRODOM; A8FPQ8.
DR   SWISS-2DPAGE; A8FPQ8.
KW   Complete proteome {ECO:0000313|Proteomes:UP000002015};
KW   Methyltransferase {ECO:0000256|PIRNR:PIRNR004553,
KW   ECO:0000313|EMBL:ABV34831.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002015};
KW   rRNA processing {ECO:0000256|PIRNR:PIRNR004553};
KW   S-adenosyl-L-methionine {ECO:0000256|PIRNR:PIRNR004553};
KW   Transferase {ECO:0000256|PIRNR:PIRNR004553,
KW   ECO:0000313|EMBL:ABV34831.1}.
SQ   SEQUENCE   193 AA;  21527 MW;  08B5056B615A350E CRC64;
     MAKNRPSSGQ VRIIAGQWRS RRLPIQDLEG LRPTTDRVRE TLFNWLAGDL TGARILDCFG
     GSGALCLESL SRYASYAKVF ELQASAAEQL KDNLKTLKCD SSTAEVIKGD TLKLLATKPS
     EGFDIIYIDP PFRKGLAEKT IQLIAGNGWL NENAQIYVET ESETAQLAVP SDWVQLKEKK
     AGQVIYRLYQ YQP
//

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