(data stored in ACNUC7421 zone)

SWISSPROT: A8FQ24_SHESH

ID   A8FQ24_SHESH            Unreviewed;       701 AA.
AC   A8FQ24;
DT   13-NOV-2007, integrated into UniProtKB/TrEMBL.
DT   13-NOV-2007, sequence version 1.
DT   05-JUL-2017, entry version 65.
DE   SubName: Full=GTP diphosphokinase {ECO:0000313|EMBL:ABV34947.1};
DE            EC=2.7.6.5 {ECO:0000313|EMBL:ABV34947.1};
GN   OrderedLocusNames=Ssed_0334 {ECO:0000313|EMBL:ABV34947.1};
OS   Shewanella sediminis (strain HAW-EB3).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC   Shewanellaceae; Shewanella.
OX   NCBI_TaxID=425104 {ECO:0000313|EMBL:ABV34947.1, ECO:0000313|Proteomes:UP000002015};
RN   [1] {ECO:0000313|EMBL:ABV34947.1, ECO:0000313|Proteomes:UP000002015}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HAW-EB3 {ECO:0000313|EMBL:ABV34947.1,
RC   ECO:0000313|Proteomes:UP000002015};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T.,
RA   Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D.,
RA   Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L.,
RA   Kyrpides N., Kim E., Zhao J.-S., Richardson P.;
RT   "Complete sequence of Shewanella sediminis HAW-EB3.";
RL   Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: In eubacteria ppGpp (guanosine 3'-diphosphate 5-'
CC       diphosphate) is a mediator of the stringent response that
CC       coordinates a variety of cellular activities in response to
CC       changes in nutritional abundance. {ECO:0000256|RuleBase:RU003847}.
CC   -!- SIMILARITY: Belongs to the relA/spoT family.
CC       {ECO:0000256|RuleBase:RU003847}.
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DR   EMBL; CP000821; ABV34947.1; -; Genomic_DNA.
DR   RefSeq; WP_012004473.1; NC_009831.1.
DR   ProteinModelPortal; A8FQ24; -.
DR   STRING; 425104.Ssed_0334; -.
DR   EnsemblBacteria; ABV34947; ABV34947; Ssed_0334.
DR   KEGG; sse:Ssed_0334; -.
DR   eggNOG; ENOG4105CWR; Bacteria.
DR   eggNOG; COG0317; LUCA.
DR   HOGENOM; HOG000018299; -.
DR   KO; K01139; -.
DR   OMA; HYYSIYQ; -.
DR   OrthoDB; POG091H01YD; -.
DR   BioCyc; SSED425104:GH7Q-343-MONOMER; -.
DR   Proteomes; UP000002015; Chromosome.
DR   GO; GO:0008728; F:GTP diphosphokinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0015969; P:guanosine tetraphosphate metabolic process; IEA:InterPro.
DR   CDD; cd05399; NT_Rel-Spo_like; 1.
DR   CDD; cd01668; TGS_RelA_SpoT; 1.
DR   Gene3D; 3.10.20.30; -; 1.
DR   InterPro; IPR002912; ACT_dom.
DR   InterPro; IPR012675; Beta-grasp_dom.
DR   InterPro; IPR003607; HD/PDEase_dom.
DR   InterPro; IPR004811; RelA/Spo_fam.
DR   InterPro; IPR007685; RelA_SpoT.
DR   InterPro; IPR004095; TGS.
DR   InterPro; IPR012676; TGS-like.
DR   InterPro; IPR033655; TGS_RelA.
DR   Pfam; PF13291; ACT_4; 1.
DR   Pfam; PF13328; HD_4; 1.
DR   Pfam; PF04607; RelA_SpoT; 1.
DR   Pfam; PF02824; TGS; 1.
DR   SMART; SM00471; HDc; 1.
DR   SMART; SM00954; RelA_SpoT; 1.
DR   SUPFAM; SSF81271; SSF81271; 1.
DR   TIGRFAMs; TIGR00691; spoT_relA; 1.
DR   PROSITE; PS51671; ACT; 1.
PE   3: Inferred from homology;
DR   PRODOM; A8FQ24.
DR   SWISS-2DPAGE; A8FQ24.
KW   Complete proteome {ECO:0000313|Proteomes:UP000002015};
KW   Kinase {ECO:0000313|EMBL:ABV34947.1};
KW   Transferase {ECO:0000313|EMBL:ABV34947.1}.
FT   DOMAIN      628    701       ACT. {ECO:0000259|PROSITE:PS51671}.
SQ   SEQUENCE   701 AA;  78920 MW;  DB4B28288F62B8AC CRC64;
     MYLFEGLKES ASGYLEPDQV ELLKQAYQVA RDAHEGQMRT SGEPYITHPV AVARILADMR
     LDHETLMAAL LHDTIEDTPV TKEELAEIFS ESIAELVEGV SKLDKLKFRD KKEAQAENFR
     KMMMAMTQDI RVILIKLADR THNMRTLGAL RPDKRRRIAR ETLEIYAPIA NRLGIHNIKI
     ELEDLGFQAY YPMRYRVLKE VVKAARGNRK ELIQSIEAAV HTRLEDTGLQ GTVKGREKNL
     YSIYNKMRSK ELQFQEVMDI YAFRVIVDSI DTCYRVMGAM HGLYKPRPGR FKDYIAIPKA
     NGYQSLHTSL FGPHAVPVEI QIRTEDMDQM ADKGVAAHWV YKKGSSAEQG TTTQVRARKW
     MQSLLELQQS ASTSFEFVEN FKTELFPEEI YVFTPEGRIL ELPVGATPVD FAYEVHTDVG
     NTCVGARVNR QAYPLSQPLI SGQTVEIITA KGARPNAAWL NFVVTGKARA KIRQILKSLK
     EVDAVALGKR LLNHALGETK LDTISAEQID SVVNDTKHNT LDELLADIGL GNAMSIVIAQ
     RLRGDQIEQH EDKDSNMMPI RGAEGMLVTF ANCCRPIPGD AVIAHVSPGK GLVVHMESCA
     NIRGYQGEPD KYIPVQWDSA EGVEYQANLR VEIVNHQGAL AKITSIVAAE GANIHNLSTE
     ERDGRVFLIN LRVSVRDRIH LANVMRRIRV LPEVLRTSRN R
//

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