(data stored in ACNUC7421 zone)

SWISSPROT: SLMA_SHESH

ID   SLMA_SHESH              Reviewed;         197 AA.
AC   A8FQ72;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   13-NOV-2007, sequence version 1.
DT   07-JUN-2017, entry version 64.
DE   RecName: Full=Nucleoid occlusion factor SlmA {ECO:0000255|HAMAP-Rule:MF_01839};
GN   Name=slmA {ECO:0000255|HAMAP-Rule:MF_01839};
GN   OrderedLocusNames=Ssed_0382;
OS   Shewanella sediminis (strain HAW-EB3).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC   Shewanellaceae; Shewanella.
OX   NCBI_TaxID=425104;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HAW-EB3;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T.,
RA   Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D.,
RA   Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L.,
RA   Kyrpides N., Kim E., Zhao J.-S., Richardson P.;
RT   "Complete sequence of Shewanella sediminis HAW-EB3.";
RL   Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for nucleoid occlusion (NO) phenomenon, which
CC       prevents Z-ring formation and cell division over the nucleoid.
CC       Acts as a DNA-associated cell division inhibitor that binds
CC       simultaneously chromosomal DNA and FtsZ, and disrupts the assembly
CC       of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed
CC       on non-Ter regions of the chromosome, preventing FtsZ
CC       polymerization at these regions. {ECO:0000255|HAMAP-
CC       Rule:MF_01839}.
CC   -!- SUBUNIT: Homodimer. Interacts with FtsZ. {ECO:0000255|HAMAP-
CC       Rule:MF_01839}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, nucleoid {ECO:0000255|HAMAP-
CC       Rule:MF_01839}.
CC   -!- SIMILARITY: Belongs to the nucleoid occlusion factor SlmA family.
CC       {ECO:0000255|HAMAP-Rule:MF_01839}.
DR   EMBL; CP000821; ABV34995.1; -; Genomic_DNA.
DR   RefSeq; WP_012140733.1; NC_009831.1.
DR   ProteinModelPortal; A8FQ72; -.
DR   SMR; A8FQ72; -.
DR   STRING; 425104.Ssed_0382; -.
DR   EnsemblBacteria; ABV34995; ABV34995; Ssed_0382.
DR   KEGG; sse:Ssed_0382; -.
DR   eggNOG; ENOG4105EC0; Bacteria.
DR   eggNOG; COG1309; LUCA.
DR   HOGENOM; HOG000266053; -.
DR   KO; K05501; -.
DR   OMA; IEQTVFG; -.
DR   OrthoDB; POG091H068M; -.
DR   Proteomes; UP000002015; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0009295; C:nucleoid; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0010974; P:negative regulation of barrier septum assembly; IEA:InterPro.
DR   HAMAP; MF_01839; NO_factor_SlmA; 1.
DR   InterPro; IPR009057; Homeobox-like.
DR   InterPro; IPR001647; HTH_TetR.
DR   InterPro; IPR023769; NO_SlmA.
DR   Pfam; PF00440; TetR_N; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   PROSITE; PS50977; HTH_TETR_2; 1.
PE   3: Inferred from homology;
DR   PRODOM; A8FQ72.
DR   SWISS-2DPAGE; A8FQ72.
KW   Cell cycle; Cell division; Complete proteome; Cytoplasm; DNA-binding.
FT   CHAIN         1    197       Nucleoid occlusion factor SlmA.
FT                                /FTId=PRO_1000088464.
FT   DOMAIN        7     67       HTH tetR-type. {ECO:0000255|HAMAP-
FT                                Rule:MF_01839}.
FT   DNA_BIND     30     49       H-T-H motif. {ECO:0000255|HAMAP-
FT                                Rule:MF_01839}.
SQ   SEQUENCE   197 AA;  22628 MW;  AE401643F0EE7703 CRC64;
     MAVSPKINRR EHILQCLATM LETNPGQRIT TAKLAAEVGV SEAALYRHFP SKARMFEGLI
     DFIEESLLSR INLIMTEEKD TMKRCQLLLQ LLLIFSERNP GISRVLNGDA LLGENERLRS
     RVSLIFSKIE THLKQILREK TLREGKGFNL DEAILANLLL AIAEGRIAQF VRSEFKQKPT
     EHFDQQWIFI QQQLLQS
//

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