(data stored in ACNUC7421 zone)

SWISSPROT: YACG_SHESH

ID   YACG_SHESH              Reviewed;          70 AA.
AC   A8FQB0;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   13-NOV-2007, sequence version 1.
DT   07-JUN-2017, entry version 68.
DE   RecName: Full=DNA gyrase inhibitor YacG {ECO:0000255|HAMAP-Rule:MF_00649};
GN   Name=yacG {ECO:0000255|HAMAP-Rule:MF_00649};
GN   OrderedLocusNames=Ssed_0420;
OS   Shewanella sediminis (strain HAW-EB3).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC   Shewanellaceae; Shewanella.
OX   NCBI_TaxID=425104;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HAW-EB3;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T.,
RA   Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D.,
RA   Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L.,
RA   Kyrpides N., Kim E., Zhao J.-S., Richardson P.;
RT   "Complete sequence of Shewanella sediminis HAW-EB3.";
RL   Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Inhibits all the catalytic activities of DNA gyrase by
CC       preventing its interaction with DNA. Acts by binding directly to
CC       the C-terminal domain of GyrB, which probably disrupts DNA binding
CC       by the gyrase. {ECO:0000255|HAMAP-Rule:MF_00649}.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00649};
CC       Note=Binds 1 zinc ion. {ECO:0000255|HAMAP-Rule:MF_00649};
CC   -!- SUBUNIT: Interacts with GyrB. {ECO:0000255|HAMAP-Rule:MF_00649}.
CC   -!- SIMILARITY: Belongs to the DNA gyrase inhibitor YacG family.
CC       {ECO:0000255|HAMAP-Rule:MF_00649}.
DR   EMBL; CP000821; ABV35033.1; -; Genomic_DNA.
DR   RefSeq; WP_012140770.1; NC_009831.1.
DR   ProteinModelPortal; A8FQB0; -.
DR   SMR; A8FQB0; -.
DR   STRING; 425104.Ssed_0420; -.
DR   EnsemblBacteria; ABV35033; ABV35033; Ssed_0420.
DR   KEGG; sse:Ssed_0420; -.
DR   eggNOG; ENOG41067SF; Bacteria.
DR   eggNOG; COG3024; LUCA.
DR   HOGENOM; HOG000255917; -.
DR   KO; K09862; -.
DR   OMA; WAAEEHK; -.
DR   OrthoDB; POG091H04DF; -.
DR   Proteomes; UP000002015; Chromosome.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   Gene3D; 3.30.50.10; -; 1.
DR   HAMAP; MF_00649; DNA_gyrase_inhibitor_YacG; 1.
DR   InterPro; IPR005584; DNA_gyrase_inhibitor_YacG.
DR   InterPro; IPR013088; Znf_NHR/GATA.
DR   Pfam; PF03884; YacG; 1.
PE   3: Inferred from homology;
DR   PRODOM; A8FQB0.
DR   SWISS-2DPAGE; A8FQB0.
KW   Complete proteome; Metal-binding; Zinc.
FT   CHAIN         1     70       DNA gyrase inhibitor YacG.
FT                                /FTId=PRO_1000082730.
FT   METAL         7      7       Zinc. {ECO:0000255|HAMAP-Rule:MF_00649}.
FT   METAL        10     10       Zinc. {ECO:0000255|HAMAP-Rule:MF_00649}.
FT   METAL        26     26       Zinc. {ECO:0000255|HAMAP-Rule:MF_00649}.
FT   METAL        30     30       Zinc. {ECO:0000255|HAMAP-Rule:MF_00649}.
SQ   SEQUENCE   70 AA;  8021 MW;  6D88D37E4D2E155F CRC64;
     MTTTVKCPTC QKEVIWNSES KFKPFCSDRC KLIDLGDWAS EKHAIPVKSE FDPETLDGLG
     YDEADFFKDQ
//

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