(data stored in ACNUC7421 zone)

SWISSPROT: UBID_SHESH

ID   UBID_SHESH              Reviewed;         493 AA.
AC   A8FQJ5;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   13-NOV-2007, sequence version 1.
DT   05-JUL-2017, entry version 67.
DE   RecName: Full=3-octaprenyl-4-hydroxybenzoate carboxy-lyase {ECO:0000255|HAMAP-Rule:MF_01636};
DE            EC=4.1.1.98 {ECO:0000255|HAMAP-Rule:MF_01636};
DE   AltName: Full=Polyprenyl p-hydroxybenzoate decarboxylase {ECO:0000255|HAMAP-Rule:MF_01636};
GN   Name=ubiD {ECO:0000255|HAMAP-Rule:MF_01636};
GN   OrderedLocusNames=Ssed_0505;
OS   Shewanella sediminis (strain HAW-EB3).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC   Shewanellaceae; Shewanella.
OX   NCBI_TaxID=425104;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HAW-EB3;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T.,
RA   Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D.,
RA   Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L.,
RA   Kyrpides N., Kim E., Zhao J.-S., Richardson P.;
RT   "Complete sequence of Shewanella sediminis HAW-EB3.";
RL   Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy
CC       benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone
CC       biosynthesis. {ECO:0000255|HAMAP-Rule:MF_01636}.
CC   -!- CATALYTIC ACTIVITY: A 4-hydroxy-3-polyprenylbenzoate = a 2-
CC       polyprenylphenol + CO(2). {ECO:0000255|HAMAP-Rule:MF_01636}.
CC   -!- COFACTOR:
CC       Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01636};
CC       Name=prenyl-FMN; Xref=ChEBI:CHEBI:87746;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01636};
CC       Note=Binds 1 prenylated FMN (prenyl-FMN) per subunit.
CC       {ECO:0000255|HAMAP-Rule:MF_01636};
CC   -!- PATHWAY: Cofactor biosynthesis; ubiquinone biosynthesis.
CC       {ECO:0000255|HAMAP-Rule:MF_01636}.
CC   -!- SUBUNIT: Homohexamer. {ECO:0000255|HAMAP-Rule:MF_01636}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01636}; Peripheral membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01636}.
CC   -!- SIMILARITY: Belongs to the UbiD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01636}.
DR   EMBL; CP000821; ABV35118.1; -; Genomic_DNA.
DR   RefSeq; WP_012140855.1; NC_009831.1.
DR   ProteinModelPortal; A8FQJ5; -.
DR   SMR; A8FQJ5; -.
DR   STRING; 425104.Ssed_0505; -.
DR   EnsemblBacteria; ABV35118; ABV35118; Ssed_0505.
DR   KEGG; sse:Ssed_0505; -.
DR   eggNOG; ENOG4105D3H; Bacteria.
DR   eggNOG; COG0043; LUCA.
DR   HOGENOM; HOG000227663; -.
DR   KO; K03182; -.
DR   OMA; IDATNKW; -.
DR   OrthoDB; POG091H05QI; -.
DR   UniPathway; UPA00232; -.
DR   Proteomes; UP000002015; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008694; F:3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity; IEA:InterPro.
DR   GO; GO:0048037; F:cofactor binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006744; P:ubiquinone biosynthetic process; IEA:UniProtKB-UniPathway.
DR   HAMAP; MF_01636; UbiD; 1.
DR   InterPro; IPR012349; Split_barrel_FMN-bd.
DR   InterPro; IPR002830; UbiD.
DR   InterPro; IPR023677; UbiD_bacteria.
DR   Pfam; PF01977; UbiD; 1.
DR   SUPFAM; SSF50475; SSF50475; 1.
DR   TIGRFAMs; TIGR00148; TIGR00148; 1.
PE   3: Inferred from homology;
DR   PRODOM; A8FQJ5.
DR   SWISS-2DPAGE; A8FQJ5.
KW   Cell membrane; Complete proteome; Decarboxylase; Lyase; Manganese;
KW   Membrane; Metal-binding; Ubiquinone biosynthesis.
FT   CHAIN         1    493       3-octaprenyl-4-hydroxybenzoate carboxy-
FT                                lyase.
FT                                /FTId=PRO_1000088194.
FT   REGION      172    177       prenyl-FMN binding. {ECO:0000255|HAMAP-
FT                                Rule:MF_01636}.
FT   REGION      194    195       prenyl-FMN binding. {ECO:0000255|HAMAP-
FT                                Rule:MF_01636}.
FT   ACT_SITE    287    287       Proton donor. {ECO:0000255|HAMAP-
FT                                Rule:MF_01636}.
FT   METAL       172    172       Manganese. {ECO:0000255|HAMAP-
FT                                Rule:MF_01636}.
FT   METAL       238    238       Manganese. {ECO:0000255|HAMAP-
FT                                Rule:MF_01636}.
SQ   SEQUENCE   493 AA;  55637 MW;  E23805258F613B1B CRC64;
     MSFKDLRSFI SHLEANGELK RISHPVDPHL EMTEIADRVL RAKGPALLFE NPVGNEMPVL
     ANLFGTPKRV AMALGKEDPL ALREVGELLA FLKEPEPPRG FKDAISKIPM FKQALNMPPK
     TVRNAPCQEV IKTGSDVDLT KLPIQHCWPG DVAPLVTWGL TITKGPRQKR QNLGIYRQQL
     LDKDKLIMRW LDHRGGALDF KDFKEKFPGE RYPVVVALGA DPVTILGAVT PVPDSMSEYA
     FAGLLRGERT DVCKAISCDL EVPATSEIIL EGYIDPEEMA EEGPYGDHTG YYNETDKFPV
     FTVTHITHRK DAIYHSTYTG RPPDEPAMLG VALNEIFVPI LRKQYPEIID FYLPPEGCSY
     RMAVISIRKE YPGHAKRVMM GAWSFLRQFM YTKFIIIVDE DVNCRDWNDV IWAITTRMDP
     KRDTVMIENT PIDYLDFASP VAGLGSKMGM DATNKWEGET DREWGTPIVM DEAVKQRIDT
     IWDDLGIDDA PTL
//

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