(data stored in ACNUC7421 zone)

SWISSPROT: A8LB31_FRASN

ID   A8LB31_FRASN            Unreviewed;       447 AA.
AC   A8LB31;
DT   04-DEC-2007, integrated into UniProtKB/TrEMBL.
DT   04-DEC-2007, sequence version 1.
DT   08-MAY-2019, entry version 87.
DE   RecName: Full=Spermidine/putrescine import ATP-binding protein PotA {ECO:0000256|RuleBase:RU364083};
DE            EC=7.6.2.11 {ECO:0000256|RuleBase:RU364083};
GN   Name=potA {ECO:0000256|RuleBase:RU364083};
GN   OrderedLocusNames=Franean1_0023 {ECO:0000313|EMBL:ABW09492.1};
OS   Frankia sp. (strain EAN1pec).
OC   Bacteria; Actinobacteria; Frankiales; Frankiaceae; Frankia.
OX   NCBI_TaxID=298653 {ECO:0000313|EMBL:ABW09492.1, ECO:0000313|Proteomes:UP000001313};
RN   [1] {ECO:0000313|Proteomes:UP000001313}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=EAN1pec {ECO:0000313|Proteomes:UP000001313};
RX   PubMed=17151343; DOI=10.1101/gr.5798407;
RA   Normand P., Lapierre P., Tisa L.S., Gogarten J.P., Alloisio N.,
RA   Bagnarol E., Bassi C.A., Berry A.M., Bickhart D.M., Choisne N.,
RA   Couloux A., Cournoyer B., Cruveiller S., Daubin V., Demange N.,
RA   Francino M.P., Goltsman E., Huang Y., Kopp O.R., Labarre L.,
RA   Lapidus A., Lavire C., Marechal J., Martinez M., Mastronunzio J.E.,
RA   Mullin B.C., Niemann J., Pujic P., Rawnsley T., Rouy Z.,
RA   Schenowitz C., Sellstedt A., Tavares F., Tomkins J.P., Vallenet D.,
RA   Valverde C., Wall L.G., Wang Y., Medigue C., Benson D.R.;
RT   "Genome characteristics of facultatively symbiotic Frankia sp. strains
RT   reflect host range and host plant biogeography.";
RL   Genome Res. 17:7-15(2007).
CC   -!- FUNCTION: Part of the ABC transporter complex PotABCD involved in
CC       spermidine/putrescine import. Responsible for energy coupling to
CC       the transport system. {ECO:0000256|RuleBase:RU364083,
CC       ECO:0000256|SAAS:SAAS00083152}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H(2)O + polyamine-[polyamine-binding protein](Side
CC         1) = ADP + phosphate + polyamine(Side 2) + [polyamine-binding
CC         protein](Side 1).; EC=7.6.2.11;
CC         Evidence={ECO:0000256|RuleBase:RU364083,
CC         ECO:0000256|SAAS:SAAS01153263};
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins
CC       (PotA), two transmembrane proteins (PotB and PotC) and a solute-
CC       binding protein (PotD). {ECO:0000256|RuleBase:RU364083,
CC       ECO:0000256|SAAS:SAAS00083151}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily.
CC       Spermidine/putrescine importer (TC 3.A.1.11.1) family.
CC       {ECO:0000256|RuleBase:RU364083, ECO:0000256|SAAS:SAAS00569590}.
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DR   EMBL; CP000820; ABW09492.1; -; Genomic_DNA.
DR   RefSeq; WP_012157469.1; NC_009921.1.
DR   STRING; 298653.Franean1_0023; -.
DR   EnsemblBacteria; ABW09492; ABW09492; Franean1_0023.
DR   KEGG; fre:Franean1_0023; -.
DR   eggNOG; ENOG4105C53; Bacteria.
DR   eggNOG; COG3842; LUCA.
DR   KO; K11072; -.
DR   OMA; TMMRMLA; -.
DR   OrthoDB; 1200451at2; -.
DR   BioCyc; FSP298653:G1G9X-23-MONOMER; -.
DR   Proteomes; UP000001313; Chromosome.
DR   GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0015417; F:polyamine-transporting ATPase activity; IEA:InterPro.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like.
DR   InterPro; IPR017871; ABC_transporter_CS.
DR   InterPro; IPR008995; Mo/tungstate-bd_C_term_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005893; Sp_pt_ABC_ATP-bd.
DR   InterPro; IPR013611; Transp-assoc_OB_typ2.
DR   Pfam; PF00005; ABC_tran; 1.
DR   Pfam; PF08402; TOBE_2; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF50331; SSF50331; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR01187; potA; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE   3: Inferred from homology;
DR   PRODOM; A8LB31.
DR   SWISS-2DPAGE; A8LB31.
KW   ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00434,
KW   ECO:0000256|RuleBase:RU364083, ECO:0000256|SAAS:SAAS00237035};
KW   Cell membrane {ECO:0000256|RuleBase:RU364083,
KW   ECO:0000256|SAAS:SAAS00458580};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001313};
KW   Membrane {ECO:0000256|RuleBase:RU364083,
KW   ECO:0000256|SAAS:SAAS00458555};
KW   Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00434,
KW   ECO:0000256|RuleBase:RU364083, ECO:0000256|SAAS:SAAS00452314};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001313};
KW   Translocase {ECO:0000256|RuleBase:RU364083,
KW   ECO:0000256|SAAS:SAAS01153264};
KW   Transport {ECO:0000256|RuleBase:RU364083,
KW   ECO:0000256|SAAS:SAAS00237071}.
FT   DOMAIN       49    283       ABC transporter. {ECO:0000259|PROSITE:
FT                                PS50893}.
FT   NP_BIND      85     92       ATP. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00434}.
SQ   SEQUENCE   447 AA;  48927 MW;  EA91ED01879DA952 CRC64;
     MPSSLSTPMS SRRSREQWRG QRGGDPGRRR PRCARVPAGR IRRTLAPAIE FVGVAKEYSS
     RAGLVGAVSR VDLSIEQGEF FSLLGPSGCG KTTTLRMIAG FEEPTRGRIL LHGRDVTAVP
     PNRRDVNLVF QSYALFPHLD VASNVAFGLR RRGVRGQELR RRVGEILELV ELSGLADRRP
     RALSGGQQQR VALARALVNR PRALLLDEPL GALDLKLRQT MQIELKRIQR EVGITFVYVT
     HDQSEALTMS DRIAVMNRGR VEQLAAPREI YERPGTRFVA GFIGTSNLLR RSVRSVDPAG
     VDGTPVAVLD SAAEERLVVP LRPELGRPAT GSELEMTVRP EKITLGVTRP NGTCCALHGR
     VTEVVYLGTY TTYTVLTHGG SEITVFWQNS ADATNIADRG DEVWLSWLPT HSFALAPSAH
     AKSTPPSALA PSGSLREDQN HTEGLAS
//

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