(data stored in ACNUC7421 zone)

SWISSPROT: A8LGG9_FRASN

ID   A8LGG9_FRASN            Unreviewed;       133 AA.
AC   A8LGG9;
DT   04-DEC-2007, integrated into UniProtKB/TrEMBL.
DT   04-DEC-2007, sequence version 1.
DT   08-MAY-2019, entry version 66.
DE   RecName: Full=Ribonuclease VapC {ECO:0000256|HAMAP-Rule:MF_00265};
DE            Short=RNase VapC {ECO:0000256|HAMAP-Rule:MF_00265};
DE            EC=3.1.-.- {ECO:0000256|HAMAP-Rule:MF_00265};
DE   AltName: Full=Toxin VapC {ECO:0000256|HAMAP-Rule:MF_00265};
GN   Name=vapC {ECO:0000256|HAMAP-Rule:MF_00265};
GN   OrderedLocusNames=Franean1_0444 {ECO:0000313|EMBL:ABW09908.1};
OS   Frankia sp. (strain EAN1pec).
OC   Bacteria; Actinobacteria; Frankiales; Frankiaceae; Frankia.
OX   NCBI_TaxID=298653 {ECO:0000313|EMBL:ABW09908.1, ECO:0000313|Proteomes:UP000001313};
RN   [1] {ECO:0000313|Proteomes:UP000001313}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=EAN1pec {ECO:0000313|Proteomes:UP000001313};
RX   PubMed=17151343; DOI=10.1101/gr.5798407;
RA   Normand P., Lapierre P., Tisa L.S., Gogarten J.P., Alloisio N.,
RA   Bagnarol E., Bassi C.A., Berry A.M., Bickhart D.M., Choisne N.,
RA   Couloux A., Cournoyer B., Cruveiller S., Daubin V., Demange N.,
RA   Francino M.P., Goltsman E., Huang Y., Kopp O.R., Labarre L.,
RA   Lapidus A., Lavire C., Marechal J., Martinez M., Mastronunzio J.E.,
RA   Mullin B.C., Niemann J., Pujic P., Rawnsley T., Rouy Z.,
RA   Schenowitz C., Sellstedt A., Tavares F., Tomkins J.P., Vallenet D.,
RA   Valverde C., Wall L.G., Wang Y., Medigue C., Benson D.R.;
RT   "Genome characteristics of facultatively symbiotic Frankia sp. strains
RT   reflect host range and host plant biogeography.";
RL   Genome Res. 17:7-15(2007).
CC   -!- FUNCTION: Toxic component of a toxin-antitoxin (TA) system. An
CC       RNase. {ECO:0000256|HAMAP-Rule:MF_00265}.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000256|HAMAP-
CC         Rule:MF_00265, ECO:0000256|SAAS:SAAS00608033};
CC   -!- SIMILARITY: Belongs to the PINc/VapC protein family.
CC       {ECO:0000256|HAMAP-Rule:MF_00265, ECO:0000256|SAAS:SAAS00541436}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; CP000820; ABW09908.1; -; Genomic_DNA.
DR   RefSeq; WP_012157884.1; NC_009921.1.
DR   STRING; 298653.Franean1_0444; -.
DR   EnsemblBacteria; ABW09908; ABW09908; Franean1_0444.
DR   KEGG; fre:Franean1_0444; -.
DR   HOGENOM; HOG000121274; -.
DR   OMA; AEYRVGI; -.
DR   OrthoDB; 1968541at2; -.
DR   BioCyc; FSP298653:G1G9X-439-MONOMER; -.
DR   Proteomes; UP000001313; Chromosome.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0004540; F:ribonuclease activity; IEA:InterPro.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR   HAMAP; MF_00265; VapC_Nob1; 1.
DR   InterPro; IPR029060; PIN-like_dom_sf.
DR   InterPro; IPR002716; PIN_dom.
DR   InterPro; IPR022907; VapC_family.
DR   Pfam; PF01850; PIN; 1.
DR   SUPFAM; SSF88723; SSF88723; 1.
PE   3: Inferred from homology;
DR   PRODOM; A8LGG9.
DR   SWISS-2DPAGE; A8LGG9.
KW   Complete proteome {ECO:0000313|Proteomes:UP000001313};
KW   Hydrolase {ECO:0000256|HAMAP-Rule:MF_00265,
KW   ECO:0000256|SAAS:SAAS00423921};
KW   Magnesium {ECO:0000256|HAMAP-Rule:MF_00265,
KW   ECO:0000256|SAAS:SAAS00541414};
KW   Metal-binding {ECO:0000256|HAMAP-Rule:MF_00265,
KW   ECO:0000256|SAAS:SAAS00423897};
KW   Nuclease {ECO:0000256|HAMAP-Rule:MF_00265,
KW   ECO:0000256|SAAS:SAAS00423900};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001313};
KW   Toxin {ECO:0000256|HAMAP-Rule:MF_00265};
KW   Toxin-antitoxin system {ECO:0000256|HAMAP-Rule:MF_00265,
KW   ECO:0000256|SAAS:SAAS00986330}.
FT   DOMAIN        6    118       PINc. {ECO:0000259|Pfam:PF01850}.
FT   METAL         8      8       Magnesium. {ECO:0000256|HAMAP-Rule:
FT                                MF_00265}.
FT   METAL        98     98       Magnesium. {ECO:0000256|HAMAP-Rule:
FT                                MF_00265}.
SQ   SEQUENCE   133 AA;  14226 MW;  1BADBCD005AAE83B CRC64;
     MGRRLILDTN VLIAYERGTI DRSALDDDEL AVAAITIAEY RVGIELADTV ERAASRARAL
     AAIESVVDVL AYTHATAVHH ARLIAHVRRT GARRGAHDLI IAAHAAETGR TVVTRDLKAG
     FAELPGILAV DTP
//

If you have problems or comments...

PBIL Back to PBIL home page