(data stored in ACNUC1104 zone)

SWISSPROT: B1K3S2_BURCC

ID   B1K3S2_BURCC            Unreviewed;       683 AA.
AC   B1K3S2;
DT   29-APR-2008, integrated into UniProtKB/TrEMBL.
DT   29-APR-2008, sequence version 1.
DT   08-MAY-2019, entry version 82.
DE   RecName: Full=RNA polymerase sigma factor RpoD {ECO:0000256|HAMAP-Rule:MF_00963};
DE   AltName: Full=Sigma-70 {ECO:0000256|HAMAP-Rule:MF_00963};
GN   Name=rpoD {ECO:0000256|HAMAP-Rule:MF_00963};
GN   OrderedLocusNames=Bcenmc03_3641 {ECO:0000313|EMBL:ACA92793.1};
OS   Burkholderia cenocepacia (strain MC0-3).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX   NCBI_TaxID=406425 {ECO:0000313|EMBL:ACA92793.1, ECO:0000313|Proteomes:UP000002169};
RN   [1] {ECO:0000313|Proteomes:UP000002169}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MC0-3 {ECO:0000313|Proteomes:UP000002169};
RA   Copeland A., Lucas S., Lapidus A., Barry K., Bruce D., Goodwin L.,
RA   Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P.,
RA   Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M.,
RA   Hauser L., Kyrpides N., Mikhailova N., Tiedje J., Richardson P.;
RT   "Complete sequence of chromosome 2 of Burkholderia cenocepacia MC0-
RT   3.";
RL   Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Sigma factors are initiation factors that promote the
CC       attachment of RNA polymerase to specific initiation sites and are
CC       then released. This sigma factor is the primary sigma factor
CC       during exponential growth. {ECO:0000256|HAMAP-Rule:MF_00963,
CC       ECO:0000256|SAAS:SAAS00535554}.
CC   -!- SUBUNIT: Interacts transiently with the RNA polymerase catalytic
CC       core. {ECO:0000256|HAMAP-Rule:MF_00963,
CC       ECO:0000256|SAAS:SAAS00003340}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00963,
CC       ECO:0000256|SAAS:SAAS00003349}.
CC   -!- SIMILARITY: Belongs to the sigma-70 factor family. RpoD/SigA
CC       subfamily. {ECO:0000256|HAMAP-Rule:MF_00963,
CC       ECO:0000256|SAAS:SAAS00535555}.
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DR   EMBL; CP000959; ACA92793.1; -; Genomic_DNA.
DR   EnsemblBacteria; ACA92793; ACA92793; Bcenmc03_3641.
DR   KEGG; bcm:Bcenmc03_3641; -.
DR   HOGENOM; HOG000270272; -.
DR   KO; K03086; -.
DR   OMA; KLPLFND; -.
DR   Proteomes; UP000002169; Chromosome 2.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0016987; F:sigma factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0001123; P:transcription initiation from bacterial-type RNA polymerase promoter; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.10.10; -; 2.
DR   HAMAP; MF_00963; Sigma70_RpoD_SigA; 1.
DR   InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR   InterPro; IPR000943; RNA_pol_sigma70.
DR   InterPro; IPR009042; RNA_pol_sigma70_r1_2.
DR   InterPro; IPR007627; RNA_pol_sigma70_r2.
DR   InterPro; IPR007624; RNA_pol_sigma70_r3.
DR   InterPro; IPR007630; RNA_pol_sigma70_r4.
DR   InterPro; IPR007631; RNA_pol_sigma_70_non-ess.
DR   InterPro; IPR007127; RNA_pol_sigma_70_r1_1.
DR   InterPro; IPR013325; RNA_pol_sigma_r2.
DR   InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR   InterPro; IPR012760; RNA_pol_sigma_RpoD_C.
DR   InterPro; IPR028630; Sigma70_RpoD.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   Pfam; PF04546; Sigma70_ner; 1.
DR   Pfam; PF03979; Sigma70_r1_1; 1.
DR   Pfam; PF00140; Sigma70_r1_2; 1.
DR   Pfam; PF04542; Sigma70_r2; 1.
DR   Pfam; PF04539; Sigma70_r3; 1.
DR   Pfam; PF04545; Sigma70_r4; 1.
DR   PRINTS; PR00046; SIGMA70FCT.
DR   SUPFAM; SSF88659; SSF88659; 2.
DR   SUPFAM; SSF88946; SSF88946; 1.
DR   TIGRFAMs; TIGR02393; RpoD_Cterm; 1.
DR   TIGRFAMs; TIGR02937; sigma70-ECF; 1.
DR   PROSITE; PS00715; SIGMA70_1; 1.
DR   PROSITE; PS00716; SIGMA70_2; 1.
PE   3: Inferred from homology;
DR   PRODOM; B1K3S2.
DR   SWISS-2DPAGE; B1K3S2.
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002169};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00963,
KW   ECO:0000256|SAAS:SAAS00003326};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00963,
KW   ECO:0000256|SAAS:SAAS00611263};
KW   Sigma factor {ECO:0000256|HAMAP-Rule:MF_00963,
KW   ECO:0000256|SAAS:SAAS00611278};
KW   Transcription {ECO:0000256|HAMAP-Rule:MF_00963,
KW   ECO:0000256|SAAS:SAAS00611290};
KW   Transcription regulation {ECO:0000256|HAMAP-Rule:MF_00963,
KW   ECO:0000256|SAAS:SAAS00611294}.
FT   DOMAIN      472    485       RNA_pol_sigma70. {ECO:0000259|PROSITE:
FT                                PS00715}.
FT   DOMAIN      641    667       RNA_pol_sigma70. {ECO:0000259|PROSITE:
FT                                PS00716}.
FT   DNA_BIND    642    661       H-T-H motif. {ECO:0000256|HAMAP-Rule:
FT                                MF_00963}.
FT   REGION      448    518       Sigma-70 factor domain-2.
FT                                {ECO:0000256|HAMAP-Rule:MF_00963}.
FT   REGION      527    603       Sigma-70 factor domain-3.
FT                                {ECO:0000256|HAMAP-Rule:MF_00963}.
FT   REGION      616    669       Sigma-70 factor domain-4.
FT                                {ECO:0000256|HAMAP-Rule:MF_00963}.
FT   COILED       55     75       {ECO:0000256|SAM:Coils}.
FT   COILED      240    267       {ECO:0000256|SAM:Coils}.
FT   COILED      335    355       {ECO:0000256|SAM:Coils}.
FT   COILED      427    454       {ECO:0000256|SAM:Coils}.
FT   COILED      642    662       {ECO:0000256|SAM:Coils}.
FT   MOTIF       472    475       Interaction with polymerase core subunit
FT                                RpoC. {ECO:0000256|HAMAP-Rule:MF_00963}.
SQ   SEQUENCE   683 AA;  77110 MW;  F9DB8E756C44D5C3 CRC64;
     MTKKLNEVSV EDDANQSDEQ PAAAAAPGKS KVRDRRAKEK ALLKEAFATS TPGTAEELEE
     RRVKLRALIK LGKERGFLTY AEINDHLPDN FTETEALEGI IGTFNDMGVA VYEQAPDAET
     LLLNDNAPAA SSDDEVEEEA EVALSTVDSE FGRTTDPVRM YMREMGTVEL LTREGEIEIA
     KRIEDGLRHM VMAISACPTT IADILAMAER VANEEIRVDE LVDGLLDPNA SDSADTDGFS
     AKEAEAIENE DEEAEEEEEE EEEEEDDGAA QASANAAQLE ALKRASLEKF SQISEWFDKM
     RRAFEKEGYK SKAYLKAQET IQSELMTIRF TARTVERLCD TLRAQVDEVR QVERQILHIV
     VDKCGMPRSE FIARFPGSET DLDWAEKITA EGHPYSAVLS RNVPAIREQQ QRLLDLQARV
     VLPLKDLKET NRQMAAGELK ARQAKREMTE ANLRLVISIA KKYTNRGLQF LDLIQEGNIG
     LMKAVDKFEY RRGYKFSTYA TWWIRQAITR SIADQARTIR IPVHMIETIN KMNRISRQIL
     QETGLEPDPA TLAEKMEMPE DKIRKIMKIA KEPISMETPI GDDDDSHLGD FIEDTNTVAP
     ADAALHASMR DVVKDVLDSL TPREAKVLRM RFGIEMSTDH TLEEVGKQFD VTRERIRQIE
     AKALRKLRHP SRSDKLKSFL EGN
//

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