(data stored in ACNUC7421 zone)

SWISSPROT: MRAZ_ECODH

ID   MRAZ_ECODH              Reviewed;         152 AA.
AC   B1XC58;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   20-MAY-2008, sequence version 1.
DT   30-AUG-2017, entry version 58.
DE   RecName: Full=Transcriptional regulator MraZ;
GN   Name=mraZ {ECO:0000255|HAMAP-Rule:MF_01008};
GN   OrderedLocusNames=ECDH10B_0063;
OS   Escherichia coli (strain K12 / DH10B).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=316385;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / DH10B;
RX   PubMed=18245285; DOI=10.1128/JB.01695-07;
RA   Durfee T., Nelson R., Baldwin S., Plunkett G. III, Burland V., Mau B.,
RA   Petrosino J.F., Qin X., Muzny D.M., Ayele M., Gibbs R.A., Csorgo B.,
RA   Posfai G., Weinstock G.M., Blattner F.R.;
RT   "The complete genome sequence of Escherichia coli DH10B: insights into
RT   the biology of a laboratory workhorse.";
RL   J. Bacteriol. 190:2597-2606(2008).
CC   -!- FUNCTION: Negatively regulates its own expression and that of the
CC       subsequent genes in the proximal part of the division and cell
CC       wall (dcw) gene cluster. Acts by binding directly to DNA. May also
CC       regulate the expression of genes outside the dcw cluster.
CC       {ECO:0000255|HAMAP-Rule:MF_01008}.
CC   -!- SUBUNIT: Forms oligomers. {ECO:0000255|HAMAP-Rule:MF_01008}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, nucleoid {ECO:0000255|HAMAP-
CC       Rule:MF_01008}.
CC   -!- SIMILARITY: Belongs to the MraZ family. {ECO:0000255|HAMAP-
CC       Rule:MF_01008}.
DR   EMBL; CP000948; ACB01262.1; -; Genomic_DNA.
DR   RefSeq; WP_001295770.1; NC_010473.1.
DR   ProteinModelPortal; B1XC58; -.
DR   SMR; B1XC58; -.
DR   EnsemblBacteria; ACB01262; ACB01262; ECDH10B_0063.
DR   KEGG; ecd:ECDH10B_0063; -.
DR   eggNOG; ENOG4108V6E; Bacteria.
DR   eggNOG; COG2001; LUCA.
DR   HOGENOM; HOG000283907; -.
DR   KO; K03925; -.
DR   OMA; FELWDEA; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0009295; C:nucleoid; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:transcription factor activity, sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   CDD; cd16321; MraZ_C; 1.
DR   CDD; cd16320; MraZ_N; 1.
DR   HAMAP; MF_01008; MraZ; 1.
DR   InterPro; IPR003444; MraZ.
DR   InterPro; IPR035644; MraZ_C.
DR   InterPro; IPR020603; MraZ_dom.
DR   InterPro; IPR035642; MraZ_N.
DR   InterPro; IPR007159; SpoVT-AbrB_dom.
DR   Pfam; PF02381; MraZ; 2.
DR   ProDom; PD006745; MraZ; 1.
DR   TIGRFAMs; TIGR00242; TIGR00242; 1.
DR   PROSITE; PS51740; SPOVT_ABRB; 2.
PE   3: Inferred from homology;
DR   PRODOM; B1XC58.
DR   SWISS-2DPAGE; B1XC58.
KW   Cytoplasm; DNA-binding; Repeat; Repressor; Transcription;
KW   Transcription regulation.
FT   CHAIN         1    152       Transcriptional regulator MraZ.
FT                                /FTId=PRO_1000134793.
FT   DOMAIN        5     52       SpoVT-AbrB 1. {ECO:0000255|PROSITE-
FT                                ProRule:PRU01076}.
FT   DOMAIN       81    124       SpoVT-AbrB 2. {ECO:0000255|PROSITE-
FT                                ProRule:PRU01076}.
SQ   SEQUENCE   152 AA;  17360 MW;  48277D972BEDC765 CRC64;
     MFRGATLVNL DSKGRLSVPT RYREQLLENA AGQMVCTIDI HHPCLLLYPL PEWEIIEQKL
     SRLSSMNPVE RRVQRLLLGH ASECQMDGAG RLLIAPVLRQ HAGLTKEVML VGQFNKFELW
     DETTWHQQVK EDIDAEQLAT GDLSERLQDL SL
//

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