(data stored in ACNUC7421 zone)

SWISSPROT: ACPH_ECODH

ID   ACPH_ECODH              Reviewed;         193 AA.
AC   B1XEZ2;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   20-MAY-2008, sequence version 1.
DT   05-JUL-2017, entry version 53.
DE   RecName: Full=Acyl carrier protein phosphodiesterase {ECO:0000255|HAMAP-Rule:MF_01950};
DE            Short=ACP phosphodiesterase {ECO:0000255|HAMAP-Rule:MF_01950};
DE            EC=3.1.4.14 {ECO:0000255|HAMAP-Rule:MF_01950};
GN   Name=acpH {ECO:0000255|HAMAP-Rule:MF_01950};
GN   OrderedLocusNames=ECDH10B_0360;
OS   Escherichia coli (strain K12 / DH10B).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=316385;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / DH10B;
RX   PubMed=18245285; DOI=10.1128/JB.01695-07;
RA   Durfee T., Nelson R., Baldwin S., Plunkett G. III, Burland V., Mau B.,
RA   Petrosino J.F., Qin X., Muzny D.M., Ayele M., Gibbs R.A., Csorgo B.,
RA   Posfai G., Weinstock G.M., Blattner F.R.;
RT   "The complete genome sequence of Escherichia coli DH10B: insights into
RT   the biology of a laboratory workhorse.";
RL   J. Bacteriol. 190:2597-2606(2008).
CC   -!- FUNCTION: Converts holo-ACP to apo-ACP by hydrolytic cleavage of
CC       the phosphopantetheine prosthetic group from ACP.
CC       {ECO:0000255|HAMAP-Rule:MF_01950}.
CC   -!- CATALYTIC ACTIVITY: Holo-[acyl-carrier-protein] + H(2)O = 4'-
CC       phosphopantetheine + apo-[acyl-carrier-protein].
CC       {ECO:0000255|HAMAP-Rule:MF_01950}.
CC   -!- SIMILARITY: Belongs to the AcpH family. {ECO:0000255|HAMAP-
CC       Rule:MF_01950}.
DR   EMBL; CP000948; ACB01532.1; -; Genomic_DNA.
DR   RefSeq; WP_001009885.1; NC_010473.1.
DR   ProteinModelPortal; B1XEZ2; -.
DR   EnsemblBacteria; ACB01532; ACB01532; ECDH10B_0360.
DR   KEGG; ecd:ECDH10B_0360; -.
DR   eggNOG; ENOG4108ZYK; Bacteria.
DR   eggNOG; COG3124; LUCA.
DR   HOGENOM; HOG000275880; -.
DR   KO; K08682; -.
DR   OMA; MNFLAHI; -.
DR   GO; GO:0008770; F:[acyl-carrier-protein] phosphodiesterase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
DR   HAMAP; MF_01950; AcpH; 1.
DR   InterPro; IPR007431; ACP_PD.
DR   InterPro; IPR023491; ACP_phosphodiesterase_gpbac.
DR   Pfam; PF04336; ACP_PD; 1.
DR   PIRSF; PIRSF011489; DUF479; 1.
PE   3: Inferred from homology;
DR   PRODOM; B1XEZ2.
DR   SWISS-2DPAGE; B1XEZ2.
KW   Fatty acid biosynthesis; Fatty acid metabolism; Hydrolase;
KW   Lipid biosynthesis; Lipid metabolism.
FT   CHAIN         1    193       Acyl carrier protein phosphodiesterase.
FT                                /FTId=PRO_1000188804.
SQ   SEQUENCE   193 AA;  22961 MW;  0DE6F0CE01D6C523 CRC64;
     MNFLAHLHLA HLAESSLSGN LLADFVRGNP EESFPPDVVA GIHMHRRIDV LTDNLPEVRE
     AREWFRSETR RVAPITLDVM WDHFLSRHWS QLSPDFPLQE FVCYAREQVM TILPDSPPRF
     INLNNYLWSE QWLVRYRDMD FIQNVLNGMA SRRPRLDALR DSWYDLDAHY DALETRFWQF
     YPRMMAQASR KAL
//

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