(data stored in ACNUC7421 zone)

SWISSPROT: KDPA_ECODH

ID   KDPA_ECODH              Reviewed;         557 AA.
AC   B1X6M9;
DT   24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT   20-MAY-2008, sequence version 1.
DT   05-JUL-2017, entry version 58.
DE   RecName: Full=Potassium-transporting ATPase potassium-binding subunit {ECO:0000255|HAMAP-Rule:MF_00275};
DE   AltName: Full=ATP phosphohydrolase [potassium-transporting] A chain {ECO:0000255|HAMAP-Rule:MF_00275};
DE   AltName: Full=Potassium-binding and translocating subunit A {ECO:0000255|HAMAP-Rule:MF_00275};
DE   AltName: Full=Potassium-translocating ATPase A chain {ECO:0000255|HAMAP-Rule:MF_00275};
GN   Name=kdpA {ECO:0000255|HAMAP-Rule:MF_00275};
GN   OrderedLocusNames=ECDH10B_0764;
OS   Escherichia coli (strain K12 / DH10B).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=316385;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / DH10B;
RX   PubMed=18245285; DOI=10.1128/JB.01695-07;
RA   Durfee T., Nelson R., Baldwin S., Plunkett G. III, Burland V., Mau B.,
RA   Petrosino J.F., Qin X., Muzny D.M., Ayele M., Gibbs R.A., Csorgo B.,
RA   Posfai G., Weinstock G.M., Blattner F.R.;
RT   "The complete genome sequence of Escherichia coli DH10B: insights into
RT   the biology of a laboratory workhorse.";
RL   J. Bacteriol. 190:2597-2606(2008).
CC   -!- FUNCTION: Part of the high-affinity ATP-driven potassium transport
CC       (or Kdp) system, which catalyzes the hydrolysis of ATP coupled
CC       with the electrogenic transport of potassium into the cytoplasm.
CC       This subunit binds and transports the potassium across the
CC       cytoplasmic membrane. {ECO:0000255|HAMAP-Rule:MF_00275}.
CC   -!- SUBUNIT: The system is composed of three essential subunits: KdpA,
CC       KdpB and KdpC. {ECO:0000255|HAMAP-Rule:MF_00275}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_00275}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_00275}.
CC   -!- SIMILARITY: Belongs to the KdpA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00275}.
DR   EMBL; CP000948; ACB01907.1; -; Genomic_DNA.
DR   RefSeq; WP_000741129.1; NC_010473.1.
DR   ProteinModelPortal; B1X6M9; -.
DR   EnsemblBacteria; ACB01907; ACB01907; ECDH10B_0764.
DR   KEGG; ecd:ECDH10B_0764; -.
DR   eggNOG; ENOG4105D9K; Bacteria.
DR   eggNOG; COG2060; LUCA.
DR   HOGENOM; HOG000244102; -.
DR   KO; K01546; -.
DR   OMA; WQNYGGE; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008556; F:potassium-transporting ATPase activity; IEA:InterPro.
DR   HAMAP; MF_00275; KdpA; 1.
DR   InterPro; IPR004623; KdpA.
DR   PANTHER; PTHR30607; PTHR30607; 1.
DR   Pfam; PF03814; KdpA; 1.
DR   PIRSF; PIRSF001294; K_ATPaseA; 1.
DR   TIGRFAMs; TIGR00680; kdpA; 1.
PE   3: Inferred from homology;
DR   PRODOM; B1X6M9.
DR   SWISS-2DPAGE; B1X6M9.
KW   Cell inner membrane; Cell membrane; Ion transport; Membrane;
KW   Potassium; Potassium transport; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN         1    557       Potassium-transporting ATPase potassium-
FT                                binding subunit.
FT                                /FTId=PRO_1000114679.
FT   TRANSMEM      5     25       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_00275}.
FT   TRANSMEM     63     83       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_00275}.
FT   TRANSMEM    132    152       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_00275}.
FT   TRANSMEM    170    190       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_00275}.
FT   TRANSMEM    253    273       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_00275}.
FT   TRANSMEM    283    303       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_00275}.
FT   TRANSMEM    329    349       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_00275}.
FT   TRANSMEM    356    376       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_00275}.
FT   TRANSMEM    379    399       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_00275}.
FT   TRANSMEM    416    436       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_00275}.
FT   TRANSMEM    484    504       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_00275}.
FT   TRANSMEM    526    546       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_00275}.
SQ   SEQUENCE   557 AA;  59189 MW;  88C397FC3D3DC17E CRC64;
     MAAQGFLLIA TFLLVLMVLA RPLGSGLARL INDIPLPGTT GVERVLFRAL GVSDREMNWK
     QYLCAILGLN MLGLAVLFFM LLGQHYLPLN PQQLPGLSWD LALNTAVSFV TNTNWQSYSG
     ETTLSYFSQM AGLTVQNFLS AASGIAVIFA LIRAFTRQSM STLGNAWVDL LRITLWVLVP
     VALLIALFFI QQGALQNFLP YQAVNTVEGA QQLLPMGPVA SQEAIKMLGT NGGGFFNANS
     SHPFENPTAL TNFVQMLAIF LIPTALCFAF GEVMGDRRQG RMLLWAMSVI FVICVGVVMW
     AEVQGNPHLL ALGTDSSINM EGKESRFGVL VSSLFAVVTT AASCGAVIAM HDSFTALGGM
     VPMWLMQIGE VVFGGVGSGL YGMMLFVLLA VFIAGLMIGR TPEYLGKKID VREMKLTALA
     ILVTPTLVLM GAALAMMTDA GRSAMLNPGP HGFSEVLYAV SSAANNNGSA FAGLSANSPF
     WNCLLAFCMF VGRFGVIIPV MAIAGSLVSK KSQAASSGTL PTHGPLFVGL LIGTVLLVGA
     LTFIPALALG PVAEYLS
//

If you have problems or comments...

PBIL Back to PBIL home page