(data stored in ACNUC29543 zone)

SWISSPROT: B2JLG2_PARP8

ID   B2JLG2_PARP8            Unreviewed;        87 AA.
AC   B2JLG2;
DT   10-JUN-2008, integrated into UniProtKB/TrEMBL.
DT   10-JUN-2008, sequence version 1.
DT   08-MAY-2019, entry version 71.
DE   RecName: Full=Translation initiation factor IF-1 {ECO:0000256|HAMAP-Rule:MF_00075};
GN   Name=infA {ECO:0000256|HAMAP-Rule:MF_00075};
GN   OrderedLocusNames=Bphy_3442 {ECO:0000313|EMBL:ACC72595.1};
OS   Paraburkholderia phymatum (strain DSM 17167 / CIP 108236 / LMG 21445 /
OS   STM815) (Burkholderia phymatum).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Paraburkholderia.
OX   NCBI_TaxID=391038 {ECO:0000313|EMBL:ACC72595.1, ECO:0000313|Proteomes:UP000001192};
RN   [1] {ECO:0000313|Proteomes:UP000001192}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 17167 / CIP 108236 / LMG 21445 / STM815
RC   {ECO:0000313|Proteomes:UP000001192};
RX   PubMed=25197461; DOI=10.4056/sigs.4861021;
RA   Moulin L., Klonowska A., Caroline B., Booth K., Vriezen J.A.,
RA   Melkonian R., James E.K., Young J.P., Bena G., Hauser L., Land M.,
RA   Kyrpides N., Bruce D., Chain P., Copeland A., Pitluck S., Woyke T.,
RA   Lizotte-Waniewski M., Bristow J., Riley M.;
RT   "Complete genome sequence of Burkholderia phymatum STM815(T), a broad
RT   host range and efficient nitrogen-fixing symbiont of Mimosa species.";
RL   Stand. Genomic Sci. 9:763-774(2014).
CC   -!- FUNCTION: One of the essential components for the initiation of
CC       protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the
CC       30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently
CC       binds. Helps modulate mRNA selection, yielding the 30S pre-
CC       initiation complex (PIC). Upon addition of the 50S ribosomal
CC       subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S
CC       translation initiation complex. {ECO:0000256|HAMAP-Rule:MF_00075,
CC       ECO:0000256|SAAS:SAAS01025699}.
CC   -!- SUBUNIT: Component of the 30S ribosomal translation pre-initiation
CC       complex which assembles on the 30S ribosome in the order IF-2 and
CC       IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can
CC       occur at any time during PIC assembly. {ECO:0000256|HAMAP-
CC       Rule:MF_00075, ECO:0000256|SAAS:SAAS00326798}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00075}.
CC   -!- SIMILARITY: Belongs to the IF-1 family. {ECO:0000256|HAMAP-
CC       Rule:MF_00075, ECO:0000256|SAAS:SAAS00571750}.
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DR   EMBL; CP001044; ACC72595.1; -; Genomic_DNA.
DR   RefSeq; WP_012402768.1; NC_010623.1.
DR   STRING; 391038.Bphy_3442; -.
DR   EnsemblBacteria; ACC72595; ACC72595; Bphy_3442.
DR   GeneID; 27743121; -.
DR   KEGG; bph:Bphy_3442; -.
DR   eggNOG; ENOG4105K9U; Bacteria.
DR   eggNOG; COG0361; LUCA.
DR   HOGENOM; HOG000221323; -.
DR   KO; K02518; -.
DR   OMA; ECLRSAM; -.
DR   OrthoDB; 2066663at2; -.
DR   BioCyc; BPHY391038:G1GBS-3541-MONOMER; -.
DR   Proteomes; UP000001192; Chromosome 2.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0043022; F:ribosome binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-UniRule.
DR   CDD; cd04451; S1_IF1; 1.
DR   HAMAP; MF_00075; IF_1; 1.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR006196; RNA-binding_domain_S1_IF1.
DR   InterPro; IPR004368; TIF_IF1.
DR   PANTHER; PTHR33370; PTHR33370; 1.
DR   Pfam; PF01176; eIF-1a; 1.
DR   SUPFAM; SSF50249; SSF50249; 1.
DR   TIGRFAMs; TIGR00008; infA; 1.
DR   PROSITE; PS50832; S1_IF1_TYPE; 1.
PE   3: Inferred from homology;
DR   PRODOM; B2JLG2.
DR   SWISS-2DPAGE; B2JLG2.
KW   Complete proteome {ECO:0000313|Proteomes:UP000001192};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00075};
KW   Initiation factor {ECO:0000256|HAMAP-Rule:MF_00075,
KW   ECO:0000256|PROSITE-ProRule:PRU00181, ECO:0000256|SAAS:SAAS00462727,
KW   ECO:0000313|EMBL:ACC72595.1};
KW   Protein biosynthesis {ECO:0000256|HAMAP-Rule:MF_00075,
KW   ECO:0000256|PROSITE-ProRule:PRU00181, ECO:0000256|SAAS:SAAS00462770};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001192};
KW   RNA-binding {ECO:0000256|HAMAP-Rule:MF_00075,
KW   ECO:0000256|SAAS:SAAS00571736};
KW   rRNA-binding {ECO:0000256|HAMAP-Rule:MF_00075,
KW   ECO:0000256|SAAS:SAAS00571793}.
FT   DOMAIN        1     72       S1-like. {ECO:0000259|PROSITE:PS50832}.
SQ   SEQUENCE   87 AA;  9892 MW;  84A2E6D0DB16D5A2 CRC64;
     MAKEELIELD GIVDEVLPDS RYRVTLDNGV VVGAYASGRM RKNHIRILAG DRVTLELSVY
     DLTKGRINFR HKDERSSGPR SAPVRRR
//

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