(data stored in ACNUC29543 zone)

SWISSPROT: B2JLK7_PARP8

ID   B2JLK7_PARP8            Unreviewed;      1052 AA.
AC   B2JLK7;
DT   10-JUN-2008, integrated into UniProtKB/TrEMBL.
DT   10-JUN-2008, sequence version 1.
DT   08-MAY-2019, entry version 56.
DE   RecName: Full=Efflux pump membrane transporter {ECO:0000256|RuleBase:RU364070};
GN   OrderedLocusNames=Bphy_3491 {ECO:0000313|EMBL:ACC72640.1};
OS   Paraburkholderia phymatum (strain DSM 17167 / CIP 108236 / LMG 21445 /
OS   STM815) (Burkholderia phymatum).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Paraburkholderia.
OX   NCBI_TaxID=391038 {ECO:0000313|EMBL:ACC72640.1, ECO:0000313|Proteomes:UP000001192};
RN   [1] {ECO:0000313|Proteomes:UP000001192}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 17167 / CIP 108236 / LMG 21445 / STM815
RC   {ECO:0000313|Proteomes:UP000001192};
RX   PubMed=25197461; DOI=10.4056/sigs.4861021;
RA   Moulin L., Klonowska A., Caroline B., Booth K., Vriezen J.A.,
RA   Melkonian R., James E.K., Young J.P., Bena G., Hauser L., Land M.,
RA   Kyrpides N., Bruce D., Chain P., Copeland A., Pitluck S., Woyke T.,
RA   Lizotte-Waniewski M., Bristow J., Riley M.;
RT   "Complete genome sequence of Burkholderia phymatum STM815(T), a broad
RT   host range and efficient nitrogen-fixing symbiont of Mimosa species.";
RL   Stand. Genomic Sci. 9:763-774(2014).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane
CC       {ECO:0000256|RuleBase:RU364070}; Multi-pass membrane protein
CC       {ECO:0000256|RuleBase:RU364070}.
CC   -!- SIMILARITY: Belongs to the resistance-nodulation-cell division
CC       (RND) (TC 2.A.6) family. {ECO:0000256|RuleBase:RU364070,
CC       ECO:0000256|SAAS:SAAS01080844}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|RuleBase:RU364070}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; CP001044; ACC72640.1; -; Genomic_DNA.
DR   RefSeq; WP_012402813.1; NC_010623.1.
DR   STRING; 391038.Bphy_3491; -.
DR   EnsemblBacteria; ACC72640; ACC72640; Bphy_3491.
DR   GeneID; 27743168; -.
DR   KEGG; bph:Bphy_3491; -.
DR   eggNOG; ENOG4105BZS; Bacteria.
DR   eggNOG; COG0841; LUCA.
DR   HOGENOM; HOG000158129; -.
DR   OMA; FFGWFNA; -.
DR   OrthoDB; 91817at2; -.
DR   BioCyc; BPHY391038:G1GBS-3589-MONOMER; -.
DR   Proteomes; UP000001192; Chromosome 2.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015562; F:efflux transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0006855; P:drug transmembrane transport; IEA:InterPro.
DR   Gene3D; 3.30.2090.10; -; 2.
DR   InterPro; IPR027463; AcrB_DN_DC_subdom.
DR   InterPro; IPR001036; Acrflvin-R.
DR   InterPro; IPR004764; HAE1.
DR   PANTHER; PTHR32063; PTHR32063; 1.
DR   Pfam; PF00873; ACR_tran; 1.
DR   PRINTS; PR00702; ACRIFLAVINRP.
DR   SUPFAM; SSF82714; SSF82714; 2.
DR   TIGRFAMs; TIGR00915; 2A0602; 1.
PE   3: Inferred from homology;
DR   PRODOM; B2JLK7.
DR   SWISS-2DPAGE; B2JLK7.
KW   Cell inner membrane {ECO:0000256|RuleBase:RU364070};
KW   Cell membrane {ECO:0000256|RuleBase:RU364070};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001192};
KW   Membrane {ECO:0000256|RuleBase:RU364070};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001192};
KW   Transmembrane {ECO:0000256|RuleBase:RU364070};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU364070};
KW   Transport {ECO:0000256|RuleBase:RU364070}.
FT   TRANSMEM     12     32       Helical. {ECO:0000256|RuleBase:RU364070}.
FT   TRANSMEM    340    359       Helical. {ECO:0000256|RuleBase:RU364070}.
FT   TRANSMEM    366    387       Helical. {ECO:0000256|RuleBase:RU364070}.
FT   TRANSMEM    434    458       Helical. {ECO:0000256|RuleBase:RU364070}.
FT   TRANSMEM    470    497       Helical. {ECO:0000256|RuleBase:RU364070}.
FT   TRANSMEM    541    558       Helical. {ECO:0000256|RuleBase:RU364070}.
FT   TRANSMEM    874    891       Helical. {ECO:0000256|RuleBase:RU364070}.
FT   TRANSMEM    898    918       Helical. {ECO:0000256|RuleBase:RU364070}.
FT   TRANSMEM    924    948       Helical. {ECO:0000256|RuleBase:RU364070}.
FT   TRANSMEM    969    990       Helical. {ECO:0000256|RuleBase:RU364070}.
FT   TRANSMEM   1002   1028       Helical. {ECO:0000256|RuleBase:RU364070}.
SQ   SEQUENCE   1052 AA;  113113 MW;  3E0D422F57595C19 CRC64;
     MAKFFIDRPI FAWVIAIILM LAGIASIFNL PISQYPTIAP PAVQISATYP GASAKTVENT
     VTQVIEQQMS GLDHLLYMSS SSDDSGSATI TLTFEAGTNP DIAQVQVQNK LQLATPLLPE
     SVQQQGTKVT KSSSSFLLVM AFVSTDGSMD RYDLANYVAS HVEDPVSRVN GVGTVQLFGS
     QFAMRVWLDA NKLNQYSLTP VDVETALTNQ NVQVAAGSLG GTPSVPGQVL QATITQATLL
     QTPEQFGNVL LKVNQDGSQV RVKDVARIEL GGENYNFDTE YNGQPTAGFG IQLATGANAL
     ETATLVRAKI DQLSKNFPHG LVVKYPYDTT PFVKMSIEEV VKTLLEGIVL VFLVMYLFLQ
     NLRATLIPTI AVPVVLLGTF AIMSAAGFSI NTLSMFGLVL AIGLLVDDAI VVVENVERVM
     SEEGLSPREA TRKAMGQITG ALVGVALVLS AVFVPVAFSG GSVGAIYRQF SLTIVAAMVL
     SVLVALVLTP ALCATILKPV PKGHHGAKTG FFGWFNRTFD NGRDRYHSGV QHVIRRSGRW
     LVLYVVVIVA VGFLFMRLPK SFLPDEDQGT MFVLVQTPPG STQETTARTL KNVTDYLLND
     EKDIVESVFT VNGFSFAGRG QNAGLAFVRM KDYSVRQHAN QKVQALVGRV FGHYASYKDA
     TVLAVNPPSI PELGTASGFD FELTDNASLG HEALMAARNQ LLGMAAKDPS LALVRPNGLS
     DTPQFKIDID REKAQALGVT VSDIDQTFSI AWASAYVNNF LDTDGRIKKV YLQGDAPFRM
     TPEDMSKWYV RGSSGTMMPL TSVASGHWIY GSPKLERYNG IASVELQGQA AAGKSTGQAM
     SAMEALAAKL PQGIGYEWTG LSFQERQSGS QAPILYGISI LVVFLCLAAL YESWSIPFAV
     ILVVPLGVIG ALLAVTMRGL ENDVFFQVGL LTTVGLSAKN AILIVEFARE LQTNERMTAM
     QAALEASRLR LRPILMTSLA FVLGVLPLAI SNGAGSSSQH AIGTGVIGGM LTATFLAVFM
     IPMFYVVIRS KFSRDGATPN STEPDVEEET AQ
//

If you have problems or comments...

PBIL Back to PBIL home page