(data stored in ACNUC7421 zone)

SWISSPROT: ADC_RALPJ

ID   ADC_RALPJ               Reviewed;         247 AA.
AC   B2UIG7;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-2008, sequence version 1.
DT   08-MAY-2019, entry version 65.
DE   RecName: Full=Probable acetoacetate decarboxylase {ECO:0000255|HAMAP-Rule:MF_00597};
DE            Short=AAD {ECO:0000255|HAMAP-Rule:MF_00597};
DE            Short=ADC {ECO:0000255|HAMAP-Rule:MF_00597};
DE            EC=4.1.1.4 {ECO:0000255|HAMAP-Rule:MF_00597};
GN   Name=adc {ECO:0000255|HAMAP-Rule:MF_00597};
GN   OrderedLocusNames=Rpic_4271;
OS   Ralstonia pickettii (strain 12J).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Ralstonia.
OX   NCBI_TaxID=402626;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=12J;
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E.,
RA   Tice H., Bruce D., Goodwin L., Pitluck S., Meincke L., Brettin T.,
RA   Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M.,
RA   Hauser L., Kyrpides N., Mikhailova N., Marsh T., Richardson P.;
RT   "Complete sequence of chromosome 2 of Ralstonia pickettii 12J.";
RL   Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Catalyzes the conversion of acetoacetate to acetone and
CC       carbon dioxide. {ECO:0000255|HAMAP-Rule:MF_00597}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=acetoacetate + H(+) = acetone + CO2;
CC         Xref=Rhea:RHEA:19729, ChEBI:CHEBI:13705, ChEBI:CHEBI:15347,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:16526; EC=4.1.1.4;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00597};
CC   -!- SIMILARITY: Belongs to the ADC family. {ECO:0000255|HAMAP-
CC       Rule:MF_00597}.
DR   EMBL; CP001069; ACD29368.1; -; Genomic_DNA.
DR   RefSeq; WP_012430305.1; NC_010678.1.
DR   SMR; B2UIG7; -.
DR   STRING; 402626.Rpic_4271; -.
DR   PRIDE; B2UIG7; -.
DR   EnsemblBacteria; ACD29368; ACD29368; Rpic_4271.
DR   GeneID; 6285765; -.
DR   KEGG; rpi:Rpic_4271; -.
DR   eggNOG; ENOG4107GD3; Bacteria.
DR   eggNOG; COG4689; LUCA.
DR   HOGENOM; HOG000063822; -.
DR   KO; K01574; -.
DR   OMA; CTPRICE; -.
DR   OrthoDB; 978501at2; -.
DR   Proteomes; UP000002566; Chromosome 2.
DR   GO; GO:0047602; F:acetoacetate decarboxylase activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 2.40.400.10; -; 1.
DR   HAMAP; MF_00597; ADC; 1.
DR   InterPro; IPR010451; Acetoacetate_decarboxylase.
DR   InterPro; IPR023653; Acetoacetate_decarboxylase_bac.
DR   InterPro; IPR023375; ADC_dom_sf.
DR   Pfam; PF06314; ADC; 1.
DR   SUPFAM; SSF160104; SSF160104; 1.
PE   3: Inferred from homology;
DR   PRODOM; B2UIG7.
DR   SWISS-2DPAGE; B2UIG7.
KW   Complete proteome; Decarboxylase; Lyase; Reference proteome;
KW   Schiff base.
FT   CHAIN         1    247       Probable acetoacetate decarboxylase.
FT                                /FTId=PRO_1000129880.
FT   ACT_SITE    116    116       Schiff-base intermediate with
FT                                acetoacetate. {ECO:0000255|HAMAP-
FT                                Rule:MF_00597}.
SQ   SEQUENCE   247 AA;  27625 MW;  1998A05FDBFD6F5F CRC64;
     MDIKTVRETA FAMPLTSPAY PPGPYRFIHR EFFIITYRTD PAKLRAMVPE PLEVPEPLVA
     YEFIRMADST GFGDYTESGQ VIPVTYEGKP GTYTLAMYLD DHPPLAGGRE MWGFPKKLAS
     PKLVTDKDTL IGTLDYGPVR VATGTMGYKH RELDLAEQKR RLERPNFLLK IIPHVDGKTA
     RICELSRNLM IDIDMKGAWT GPASLELAHH ALAPVAELPV LEIVEARHII ADLTLGMGEV
     VFDYLAQ
//

If you have problems or comments...

PBIL Back to PBIL home page