(data stored in ACNUC7421 zone)

SWISSPROT: B4SR29_STRM5

ID   B4SR29_STRM5            Unreviewed;       301 AA.
AC   B4SR29;
DT   23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT   23-SEP-2008, sequence version 1.
DT   08-MAY-2019, entry version 61.
DE   RecName: Full=Non-homologous end joining protein Ku {ECO:0000256|HAMAP-Rule:MF_01875};
GN   Name=ku {ECO:0000256|HAMAP-Rule:MF_01875};
GN   OrderedLocusNames=Smal_0025 {ECO:0000313|EMBL:ACF49730.1};
OS   Stenotrophomonas maltophilia (strain R551-3).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Xanthomonadales;
OC   Xanthomonadaceae; Stenotrophomonas;
OC   Stenotrophomonas maltophilia group.
OX   NCBI_TaxID=391008 {ECO:0000313|EMBL:ACF49730.1, ECO:0000313|Proteomes:UP000001867};
RN   [1] {ECO:0000313|EMBL:ACF49730.1, ECO:0000313|Proteomes:UP000001867}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=R551-3 {ECO:0000313|EMBL:ACF49730.1,
RC   ECO:0000313|Proteomes:UP000001867};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E.,
RA   Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L.,
RA   Lang D., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Mikhailova N., Taghavi S., Monchy S., Newman L., Vangronsveld J.,
RA   van der Lelie D., Richardson P.;
RT   "Complete sequence of Stenotrophomonas maltophilia R551-3.";
RL   Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: With LigD forms a non-homologous end joining (NHEJ) DNA
CC       repair enzyme, which repairs dsDNA breaks with reduced fidelity.
CC       Binds linear dsDNA with 5'- and 3'- overhangs but not closed
CC       circular dsDNA nor ssDNA. Recruits and stimulates the ligase
CC       activity of LigD. {ECO:0000256|HAMAP-Rule:MF_01875}.
CC   -!- SUBUNIT: Homodimer. Interacts with LigD. {ECO:0000256|HAMAP-
CC       Rule:MF_01875}.
CC   -!- SIMILARITY: Belongs to the prokaryotic Ku family.
CC       {ECO:0000256|HAMAP-Rule:MF_01875}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; CP001111; ACF49730.1; -; Genomic_DNA.
DR   RefSeq; WP_004132923.1; NC_011071.1.
DR   STRING; 391008.Smal_0025; -.
DR   EnsemblBacteria; ACF49730; ACF49730; Smal_0025.
DR   KEGG; smt:Smal_0025; -.
DR   eggNOG; ENOG4105FDF; Bacteria.
DR   eggNOG; COG1273; LUCA.
DR   HOGENOM; HOG000237248; -.
DR   KO; K10979; -.
DR   OMA; IWKGAVS; -.
DR   OrthoDB; 1724780at2; -.
DR   BioCyc; SMAL391008:SMAL_RS00125-MONOMER; -.
DR   Proteomes; UP000001867; Chromosome.
DR   GO; GO:0003690; F:double-stranded DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006303; P:double-strand break repair via nonhomologous end joining; IEA:UniProtKB-UniRule.
DR   CDD; cd00789; KU_like; 1.
DR   Gene3D; 2.40.290.10; -; 1.
DR   HAMAP; MF_01875; Prokaryotic_Ku; 1.
DR   InterPro; IPR006164; Ku70/Ku80_beta-barrel_dom.
DR   InterPro; IPR009187; Prok_Ku.
DR   InterPro; IPR016194; SPOC-like_C_dom_sf.
DR   PANTHER; PTHR41251; PTHR41251; 1.
DR   Pfam; PF02735; Ku; 1.
DR   PIRSF; PIRSF006493; Prok_Ku; 1.
DR   SMART; SM00559; Ku78; 1.
DR   SUPFAM; SSF100939; SSF100939; 1.
DR   TIGRFAMs; TIGR02772; Ku_bact; 1.
PE   3: Inferred from homology;
DR   PRODOM; B4SR29.
DR   SWISS-2DPAGE; B4SR29.
KW   Complete proteome {ECO:0000313|Proteomes:UP000001867};
KW   DNA damage {ECO:0000256|HAMAP-Rule:MF_01875};
KW   DNA recombination {ECO:0000256|HAMAP-Rule:MF_01875};
KW   DNA repair {ECO:0000256|HAMAP-Rule:MF_01875};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_01875}.
FT   DOMAIN       53    181       Ku. {ECO:0000259|SMART:SM00559}.
SQ   SEQUENCE   301 AA;  34120 MW;  734C94790A27E7FF CRC64;
     MARPIWTGTL SFGLLNVPVS LMSGERKVDL QFRMLDSRDR KPIRFERVNA DTGEEVPWKD
     IVKAYEYDKG SYVVLEEGDI RSAAPESHEA VEVESFVDAA QIDPRYYEKP YLLVPGKKAE
     KGYVLLRETL RSTGKVGIAR VVVRTREYLC AVMPHEDALV LMILRYPQEL VDPEDYKLPT
     GKLSDYRITS KETAMAEQLI ESMAGDWDPS QYHDEFRERL QLVLNKRIKS KGGTTRVEDE
     PSPREDATTN VVDFMALLQK SLDANKRTPA KKTATRKAPA KKAAKKAAKK AVKKTTRRKA
     G
//

If you have problems or comments...

PBIL Back to PBIL home page