(data stored in ACNUC7421 zone)

SWISSPROT: B4STA0_STRM5

ID   B4STA0_STRM5            Unreviewed;       306 AA.
AC   B4STA0;
DT   23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT   23-SEP-2008, sequence version 1.
DT   08-MAY-2019, entry version 77.
DE   RecName: Full=Arginase {ECO:0000256|RuleBase:RU361159};
DE            EC=3.5.3.1 {ECO:0000256|RuleBase:RU361159};
GN   OrderedLocusNames=Smal_0238 {ECO:0000313|EMBL:ACF49943.1};
OS   Stenotrophomonas maltophilia (strain R551-3).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Xanthomonadales;
OC   Xanthomonadaceae; Stenotrophomonas;
OC   Stenotrophomonas maltophilia group.
OX   NCBI_TaxID=391008 {ECO:0000313|EMBL:ACF49943.1, ECO:0000313|Proteomes:UP000001867};
RN   [1] {ECO:0000313|EMBL:ACF49943.1, ECO:0000313|Proteomes:UP000001867}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=R551-3 {ECO:0000313|EMBL:ACF49943.1,
RC   ECO:0000313|Proteomes:UP000001867};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E.,
RA   Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L.,
RA   Lang D., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Mikhailova N., Taghavi S., Monchy S., Newman L., Vangronsveld J.,
RA   van der Lelie D., Richardson P.;
RT   "Complete sequence of Stenotrophomonas maltophilia R551-3.";
RL   Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H2O + L-arginine = L-ornithine + urea;
CC         Xref=Rhea:RHEA:20569, ChEBI:CHEBI:15377, ChEBI:CHEBI:16199,
CC         ChEBI:CHEBI:32682, ChEBI:CHEBI:46911; EC=3.5.3.1;
CC         Evidence={ECO:0000256|RuleBase:RU361159};
CC   -!- COFACTOR:
CC       Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC         Evidence={ECO:0000256|RuleBase:RU361159};
CC       Note=Binds 2 manganese ions per subunit.
CC       {ECO:0000256|RuleBase:RU361159};
CC   -!- SIMILARITY: Belongs to the arginase family. {ECO:0000256|PROSITE-
CC       ProRule:PRU00742, ECO:0000256|RuleBase:RU003684}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; CP001111; ACF49943.1; -; Genomic_DNA.
DR   RefSeq; WP_004137058.1; NC_011071.1.
DR   STRING; 391008.Smal_0238; -.
DR   EnsemblBacteria; ACF49943; ACF49943; Smal_0238.
DR   KEGG; smt:Smal_0238; -.
DR   eggNOG; ENOG4105CYW; Bacteria.
DR   eggNOG; COG0010; LUCA.
DR   HOGENOM; HOG000204319; -.
DR   KO; K01476; -.
DR   OMA; GATYREA; -.
DR   OrthoDB; 1598732at2; -.
DR   BioCyc; SMAL391008:SMAL_RS01210-MONOMER; -.
DR   Proteomes; UP000001867; Chromosome.
DR   GO; GO:0004053; F:arginase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006525; P:arginine metabolic process; IEA:UniProtKB-KW.
DR   CDD; cd09989; Arginase; 1.
DR   InterPro; IPR014033; Arginase.
DR   InterPro; IPR006035; Ureohydrolase.
DR   InterPro; IPR023696; Ureohydrolase_dom_sf.
DR   InterPro; IPR020855; Ureohydrolase_Mn_BS.
DR   Pfam; PF00491; Arginase; 1.
DR   PIRSF; PIRSF036979; Arginase; 1.
DR   PRINTS; PR00116; ARGINASE.
DR   SUPFAM; SSF52768; SSF52768; 1.
DR   TIGRFAMs; TIGR01229; rocF_arginase; 1.
DR   PROSITE; PS01053; ARGINASE_1; 1.
DR   PROSITE; PS51409; ARGINASE_2; 1.
PE   3: Inferred from homology;
DR   PRODOM; B4STA0.
DR   SWISS-2DPAGE; B4STA0.
KW   Arginine metabolism {ECO:0000256|RuleBase:RU361159};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001867};
KW   Hydrolase {ECO:0000256|RuleBase:RU003684};
KW   Manganese {ECO:0000256|RuleBase:RU361159};
KW   Metal-binding {ECO:0000256|RuleBase:RU361159}.
SQ   SEQUENCE   306 AA;  32890 MW;  5D4DC3BBF60D4613 CRC64;
     MAHPISVSLI GVPTDVGAGH RGARLGPEAL RVAGLPEALE ARGVDVRDLG NLDGPRNPWT
     APVEGYRHLD EVVAWNHALM EASYAELQAG RMPIMLGGDH CLGIGSITAV ARWCREQGKT
     LRVLWLDAHS DFNTSDVTPS GNIHGMPVAC LCGLGPDALT RLGGTVPAIT PAQMHQIGIR
     SVDPEEKRLI KTHKVDVYDM RYIDENGMKR TVEAALAGID ENTHLHVSFD VDFLDPSIAP
     GVGTTVPGGV NYREAQLVME MIADTGRMGS LDIVELNPLL DKQNATAELA VDLVESLFGK
     STLMRD
//

If you have problems or comments...

PBIL Back to PBIL home page