(data stored in ACNUC7421 zone)

SWISSPROT: B4SIH2_STRM5

ID   B4SIH2_STRM5            Unreviewed;       448 AA.
AC   B4SIH2;
DT   23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT   23-SEP-2008, sequence version 1.
DT   16-JAN-2019, entry version 77.
DE   SubName: Full=Integral membrane sensor signal transduction histidine kinase {ECO:0000313|EMBL:ACF50177.1};
GN   OrderedLocusNames=Smal_0472 {ECO:0000313|EMBL:ACF50177.1};
OS   Stenotrophomonas maltophilia (strain R551-3).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Xanthomonadales;
OC   Xanthomonadaceae; Stenotrophomonas;
OC   Stenotrophomonas maltophilia group.
OX   NCBI_TaxID=391008 {ECO:0000313|EMBL:ACF50177.1, ECO:0000313|Proteomes:UP000001867};
RN   [1] {ECO:0000313|EMBL:ACF50177.1, ECO:0000313|Proteomes:UP000001867}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=R551-3 {ECO:0000313|EMBL:ACF50177.1,
RC   ECO:0000313|Proteomes:UP000001867};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E.,
RA   Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L.,
RA   Lang D., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Mikhailova N., Taghavi S., Monchy S., Newman L., Vangronsveld J.,
RA   van der Lelie D., Richardson P.;
RT   "Complete sequence of Stenotrophomonas maltophilia R551-3.";
RL   Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC         histidine.; EC=2.7.13.3;
CC         Evidence={ECO:0000256|SAAS:SAAS01126420};
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; CP001111; ACF50177.1; -; Genomic_DNA.
DR   RefSeq; WP_012509952.1; NC_011071.1.
DR   STRING; 391008.Smal_0472; -.
DR   EnsemblBacteria; ACF50177; ACF50177; Smal_0472.
DR   KEGG; smt:Smal_0472; -.
DR   eggNOG; ENOG4105JJR; Bacteria.
DR   eggNOG; ENOG4111IA6; LUCA.
DR   HOGENOM; HOG000056840; -.
DR   KO; K07639; -.
DR   OMA; INDIHQS; -.
DR   OrthoDB; 1827824at2; -.
DR   BioCyc; SMAL391008:SMAL_RS02425-MONOMER; -.
DR   Proteomes; UP000001867; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   CDD; cd06225; HAMP; 1.
DR   CDD; cd00075; HATPase_c; 1.
DR   CDD; cd00082; HisKA; 1.
DR   Gene3D; 3.30.565.10; -; 1.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR005467; His_kinase_dom.
DR   InterPro; IPR003661; HisK_dim/P.
DR   InterPro; IPR036097; HisK_dim/P_sf.
DR   InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF02518; HATPase_c; 1.
DR   Pfam; PF00512; HisKA; 1.
DR   PRINTS; PR00344; BCTRLSENSOR.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM00387; HATPase_c; 1.
DR   SMART; SM00388; HisKA; 1.
DR   SUPFAM; SSF47384; SSF47384; 1.
DR   SUPFAM; SSF55874; SSF55874; 1.
DR   PROSITE; PS50885; HAMP; 1.
DR   PROSITE; PS50109; HIS_KIN; 1.
PE   4: Predicted;
DR   PRODOM; B4SIH2.
DR   SWISS-2DPAGE; B4SIH2.
KW   ATP-binding {ECO:0000256|SAAS:SAAS00925949};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001867};
KW   Kinase {ECO:0000256|SAAS:SAAS01003914, ECO:0000313|EMBL:ACF50177.1};
KW   Membrane {ECO:0000256|SAAS:SAAS00925724, ECO:0000256|SAM:Phobius};
KW   Nucleotide-binding {ECO:0000256|SAAS:SAAS00925310};
KW   Transferase {ECO:0000256|SAAS:SAAS01003669};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00926038,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00926160,
KW   ECO:0000256|SAM:Phobius};
KW   Two-component regulatory system {ECO:0000256|SAAS:SAAS00924981}.
FT   TRANSMEM     12     37       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    151    173       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      174    226       HAMP. {ECO:0000259|PROSITE:PS50885}.
FT   DOMAIN      234    438       Histidine kinase. {ECO:0000259|PROSITE:
FT                                PS50109}.
SQ   SEQUENCE   448 AA;  49224 MW;  2DD1364DD75DD70E CRC64;
     MKRTPSAMRG HAFHFLRYGI GFLVAHLLLI VLGLWAWDAL LEDRTEASLL AEMRGTHALL
     QQRFAETPRD QWPALARGLD ADFAYALRMV PLAEAEKALS ASQRPPFNNG RVQIDLEHMR
     SLQRIGDSGY AVMLGPLDEA LPEEGWQDSE VSGVAILLLI LMVAVALPMY VMVYRLWRDV
     SQLAQAARQM RDGQLDTRAP RAGTALVRPL ANAFNHMAEQ LQQLLESQRV LAQAVAHEVR
     TPLARMRFGL ADLEDTALDE IQRDALGGLR TDVDRLQHLT DAGVEYAALG RCHQLTRQRL
     QLAALVRGVV AQFAPLPMPV QQVLSPTGLV NVNRHMLELA LRNLLGNALR YARRQIRIAS
     TVNDGWLCLQ VEDDGPGIAP ELRGQVLQPY VRLDPGSPGF GLGLALVQVV ADKHGGHVEV
     TDSELGGACI RLHLPLESGG AVESEAAC
//

If you have problems or comments...

PBIL Back to PBIL home page