(data stored in ACNUC7421 zone)

SWISSPROT: B4SJ77_STRM5

ID   B4SJ77_STRM5            Unreviewed;       325 AA.
AC   B4SJ77;
DT   23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT   23-SEP-2008, sequence version 1.
DT   08-MAY-2019, entry version 84.
DE   RecName: Full=Tyrosine recombinase XerD {ECO:0000256|HAMAP-Rule:MF_01807};
GN   Name=xerD {ECO:0000256|HAMAP-Rule:MF_01807};
GN   OrderedLocusNames=Smal_0540 {ECO:0000313|EMBL:ACF50245.1};
OS   Stenotrophomonas maltophilia (strain R551-3).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Xanthomonadales;
OC   Xanthomonadaceae; Stenotrophomonas;
OC   Stenotrophomonas maltophilia group.
OX   NCBI_TaxID=391008 {ECO:0000313|EMBL:ACF50245.1, ECO:0000313|Proteomes:UP000001867};
RN   [1] {ECO:0000313|EMBL:ACF50245.1, ECO:0000313|Proteomes:UP000001867}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=R551-3 {ECO:0000313|EMBL:ACF50245.1,
RC   ECO:0000313|Proteomes:UP000001867};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E.,
RA   Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L.,
RA   Lang D., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Mikhailova N., Taghavi S., Monchy S., Newman L., Vangronsveld J.,
RA   van der Lelie D., Richardson P.;
RT   "Complete sequence of Stenotrophomonas maltophilia R551-3.";
RL   Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Site-specific tyrosine recombinase, which acts by
CC       catalyzing the cutting and rejoining of the recombining DNA
CC       molecules. The XerC-XerD complex is essential to convert dimers of
CC       the bacterial chromosome into monomers to permit their segregation
CC       at cell division. It also contributes to the segregational
CC       stability of plasmids. {ECO:0000256|HAMAP-Rule:MF_01807}.
CC   -!- SUBUNIT: Forms a cyclic heterotetrameric complex composed of two
CC       molecules of XerC and two molecules of XerD. {ECO:0000256|HAMAP-
CC       Rule:MF_01807, ECO:0000256|SAAS:SAAS00608017}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01807,
CC       ECO:0000256|SAAS:SAAS00019473}.
CC   -!- SIMILARITY: Belongs to the 'phage' integrase family. XerD
CC       subfamily. {ECO:0000256|HAMAP-Rule:MF_01807}.
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DR   EMBL; CP001111; ACF50245.1; -; Genomic_DNA.
DR   RefSeq; WP_012510008.1; NC_011071.1.
DR   STRING; 391008.Smal_0540; -.
DR   EnsemblBacteria; ACF50245; ACF50245; Smal_0540.
DR   KEGG; smt:Smal_0540; -.
DR   eggNOG; ENOG4105C13; Bacteria.
DR   eggNOG; COG4974; LUCA.
DR   HOGENOM; HOG000045296; -.
DR   KO; K04763; -.
DR   OMA; AFWYLIK; -.
DR   OrthoDB; 745068at2; -.
DR   BioCyc; SMAL391008:SMAL_RS02760-MONOMER; -.
DR   Proteomes; UP000001867; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0009037; F:tyrosine-based site-specific recombinase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006313; P:transposition, DNA-mediated; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.150.130; -; 1.
DR   Gene3D; 1.10.443.10; -; 1.
DR   HAMAP; MF_01808; Recomb_XerC_XerD; 1.
DR   HAMAP; MF_01807; Recomb_XerD; 1.
DR   InterPro; IPR011010; DNA_brk_join_enz.
DR   InterPro; IPR013762; Integrase-like_cat_sf.
DR   InterPro; IPR002104; Integrase_catalytic.
DR   InterPro; IPR010998; Integrase_recombinase_N.
DR   InterPro; IPR004107; Integrase_SAM-like_N.
DR   InterPro; IPR011932; Recomb_XerD.
DR   InterPro; IPR023009; Tyrosine_recombinase_XerC/XerD.
DR   Pfam; PF02899; Phage_int_SAM_1; 1.
DR   Pfam; PF00589; Phage_integrase; 1.
DR   SUPFAM; SSF56349; SSF56349; 1.
DR   TIGRFAMs; TIGR02225; recomb_XerD; 1.
PE   3: Inferred from homology;
DR   PRODOM; B4SJ77.
DR   SWISS-2DPAGE; B4SJ77.
KW   Cell cycle {ECO:0000256|HAMAP-Rule:MF_01807,
KW   ECO:0000256|SAAS:SAAS00608023};
KW   Cell division {ECO:0000256|HAMAP-Rule:MF_01807,
KW   ECO:0000256|SAAS:SAAS00608024};
KW   Chromosome partition {ECO:0000256|HAMAP-Rule:MF_01807,
KW   ECO:0000256|SAAS:SAAS00608018};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001867};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01807,
KW   ECO:0000256|SAAS:SAAS00094312};
KW   DNA integration {ECO:0000256|HAMAP-Rule:MF_01807,
KW   ECO:0000256|SAAS:SAAS00298355};
KW   DNA recombination {ECO:0000256|HAMAP-Rule:MF_01807,
KW   ECO:0000256|SAAS:SAAS00019433};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_01807,
KW   ECO:0000256|SAAS:SAAS00424103}.
FT   DOMAIN       28    109       Integrase_SAM-like_N. {ECO:0000259|Pfam:
FT                                PF02899}.
FT   DOMAIN      132    310       Phage_integrase. {ECO:0000259|Pfam:
FT                                PF00589}.
FT   ACT_SITE    168    168       {ECO:0000256|HAMAP-Rule:MF_01807}.
FT   ACT_SITE    192    192       {ECO:0000256|HAMAP-Rule:MF_01807}.
FT   ACT_SITE    271    271       {ECO:0000256|HAMAP-Rule:MF_01807}.
FT   ACT_SITE    274    274       {ECO:0000256|HAMAP-Rule:MF_01807}.
FT   ACT_SITE    297    297       {ECO:0000256|HAMAP-Rule:MF_01807}.
FT   ACT_SITE    306    306       O-(3'-phospho-DNA)-tyrosine intermediate.
FT                                {ECO:0000256|HAMAP-Rule:MF_01807}.
SQ   SEQUENCE   325 AA;  36307 MW;  842B9AD357C71F92 CRC64;
     MAPVSTPAER RQLVQQLPEL RADDSLRIQR FLDAIWAENG LARATLDSYR RDLEGLARWT
     DGREGGLAGI ERPGLFDYLA WRTRHGWSPR SNARLLSALR AFFADGVRRG DRSEDPSALL
     DPPKLPRLLP KALAESQIDA LLAAPDIDSP LGLRDRAMLE LMYAAGLRVS ELVLLPATAV
     NLRQGVLRVT GKGSKERLVP LGEESQHWLE RYLQQSRPQL VGKGKVQALA DGQTPLFIEP
     TLHALTRQAF WHLVKRHAQV AGIDPARISP HALRHSFATH LLNRGADLRA LQMLLGHSSL
     STTQIYTLVA REHLQKLHAR HHPRG
//

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