(data stored in ACNUC7421 zone)

SWISSPROT: B8IT14_METNO

ID   B8IT14_METNO            Unreviewed;       317 AA.
AC   B8IT14;
DT   03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   03-MAR-2009, sequence version 1.
DT   07-JUN-2017, entry version 55.
DE   RecName: Full=Ribosomal RNA small subunit methyltransferase I {ECO:0000256|HAMAP-Rule:MF_01877};
DE            EC=2.1.1.198 {ECO:0000256|HAMAP-Rule:MF_01877};
DE   AltName: Full=16S rRNA 2'-O-ribose C1402 methyltransferase {ECO:0000256|HAMAP-Rule:MF_01877};
DE   AltName: Full=rRNA (cytidine-2'-O-)-methyltransferase RsmI {ECO:0000256|HAMAP-Rule:MF_01877};
GN   Name=rsmI {ECO:0000256|HAMAP-Rule:MF_01877};
GN   OrderedLocusNames=Mnod_0025 {ECO:0000313|EMBL:ACL55076.1};
OS   Methylobacterium nodulans (strain LMG 21967 / CNCM I-2342 / ORS 2060).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Methylobacteriaceae; Methylobacterium.
OX   NCBI_TaxID=460265 {ECO:0000313|EMBL:ACL55076.1, ECO:0000313|Proteomes:UP000008207};
RN   [1] {ECO:0000313|EMBL:ACL55076.1, ECO:0000313|Proteomes:UP000008207}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LMG 21967 / CNCM I-2342 / ORS 2060
RC   {ECO:0000313|Proteomes:UP000008207};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E.,
RA   Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T.,
RA   Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Ivanova N., Marx C.J., Richardson P.;
RT   "Complete sequence of chromosome of Methylobacterium nodulans ORS
RT   2060.";
RL   Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Catalyzes the 2'-O-methylation of the ribose of cytidine
CC       1402 (C1402) in 16S rRNA. {ECO:0000256|HAMAP-Rule:MF_01877}.
CC   -!- CATALYTIC ACTIVITY: S-adenosyl-L-methionine + cytidine(1402) in
CC       16S rRNA = S-adenosyl-L-homocysteine + 2'-O-methylcytidine(1402)
CC       in 16S rRNA. {ECO:0000256|HAMAP-Rule:MF_01877}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01877}.
CC   -!- SIMILARITY: Belongs to the methyltransferase superfamily. RsmI
CC       family. {ECO:0000256|HAMAP-Rule:MF_01877}.
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DR   EMBL; CP001349; ACL55076.1; -; Genomic_DNA.
DR   RefSeq; WP_012634315.1; NC_011894.1.
DR   ProteinModelPortal; B8IT14; -.
DR   STRING; 460265.Mnod_0025; -.
DR   EnsemblBacteria; ACL55076; ACL55076; Mnod_0025.
DR   KEGG; mno:Mnod_0025; -.
DR   eggNOG; ENOG4105CU0; Bacteria.
DR   eggNOG; COG0313; LUCA.
DR   HOGENOM; HOG000195941; -.
DR   KO; K07056; -.
DR   OMA; RTMVFFE; -.
DR   OrthoDB; POG091H005X; -.
DR   Proteomes; UP000008207; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0070677; F:rRNA (cytosine-2'-O-)-methyltransferase activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0000453; P:enzyme-directed rRNA 2'-O-methylation; IEA:UniProtKB-HAMAP.
DR   CDD; cd11648; RsmI; 1.
DR   Gene3D; 3.30.950.10; -; 1.
DR   Gene3D; 3.40.1010.10; -; 1.
DR   HAMAP; MF_01877; 16SrRNA_methyltr_I; 1.
DR   InterPro; IPR000878; 4pyrrol_Mease.
DR   InterPro; IPR014777; 4pyrrole_Mease_sub1.
DR   InterPro; IPR014776; 4pyrrole_Mease_sub2.
DR   InterPro; IPR008189; rRNA_ssu_MeTfrase_I.
DR   InterPro; IPR018063; SAM_MeTrfase_RsmI_CS.
DR   Pfam; PF00590; TP_methylase; 1.
DR   PIRSF; PIRSF005917; MTase_YraL; 1.
DR   SUPFAM; SSF53790; SSF53790; 1.
DR   TIGRFAMs; TIGR00096; TIGR00096; 1.
DR   PROSITE; PS01296; RSMI; 1.
PE   3: Inferred from homology;
DR   PRODOM; B8IT14.
DR   SWISS-2DPAGE; B8IT14.
KW   Complete proteome {ECO:0000313|Proteomes:UP000008207};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01877};
KW   Methyltransferase {ECO:0000256|HAMAP-Rule:MF_01877,
KW   ECO:0000313|EMBL:ACL55076.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008207};
KW   rRNA processing {ECO:0000256|HAMAP-Rule:MF_01877};
KW   S-adenosyl-L-methionine {ECO:0000256|HAMAP-Rule:MF_01877};
KW   Transferase {ECO:0000256|HAMAP-Rule:MF_01877,
KW   ECO:0000313|EMBL:ACL55076.1}.
FT   DOMAIN       38    237       TP_methylase. {ECO:0000259|Pfam:PF00590}.
SQ   SEQUENCE   317 AA;  32799 MW;  32DFF8956422273F CRC64;
     MSDRADDPPR RPDAPGRGPA VYTAFGLAAE AEPLAPGLHV VATPIGNLKD VTFRALGTLA
     AADAVLAEDT RVTRTLLAHY GITTPLVSYH EHSGEAVRER MVARMKAGEA LALVSDAGTP
     LVSDPGFKLV QAAIAAGLSV TPVPGPSAAI TALMAAGLPT DRFFFEGFLP QKAGARRNRL
     AALASVPGTL VLFEAPHRLP EMLADAAEML GGGRSAAVAR ELTKLFETVR RGDLASLAAE
     FAASGPPKGE VVVVIGAAVE GAPGPEADAD LDARLTAALA RHSIKDAAAL VADETGQKRR
     DVYARALALT RRADDED
//

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