(data stored in ACNUC7421 zone)

SWISSPROT: RF1_METNO

ID   RF1_METNO               Reviewed;         359 AA.
AC   B8IUB4;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   03-MAR-2009, sequence version 1.
DT   07-JUN-2017, entry version 55.
DE   RecName: Full=Peptide chain release factor 1 {ECO:0000255|HAMAP-Rule:MF_00093};
DE            Short=RF-1 {ECO:0000255|HAMAP-Rule:MF_00093};
GN   Name=prfA {ECO:0000255|HAMAP-Rule:MF_00093};
GN   OrderedLocusNames=Mnod_0112;
OS   Methylobacterium nodulans (strain LMG 21967 / CNCM I-2342 / ORS 2060).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Methylobacteriaceae; Methylobacterium.
OX   NCBI_TaxID=460265;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LMG 21967 / CNCM I-2342 / ORS 2060;
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E.,
RA   Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T.,
RA   Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Ivanova N., Marx C.J., Richardson P.;
RT   "Complete sequence of chromosome of Methylobacterium nodulans ORS
RT   2060.";
RL   Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Peptide chain release factor 1 directs the termination
CC       of translation in response to the peptide chain termination codons
CC       UAG and UAA. {ECO:0000255|HAMAP-Rule:MF_00093}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00093}.
CC   -!- PTM: Methylated by PrmC. Methylation increases the termination
CC       efficiency of RF1. {ECO:0000255|HAMAP-Rule:MF_00093}.
CC   -!- SIMILARITY: Belongs to the prokaryotic/mitochondrial release
CC       factor family. {ECO:0000255|HAMAP-Rule:MF_00093}.
DR   EMBL; CP001349; ACL55159.1; -; Genomic_DNA.
DR   RefSeq; WP_012634398.1; NC_011894.1.
DR   ProteinModelPortal; B8IUB4; -.
DR   SMR; B8IUB4; -.
DR   STRING; 460265.Mnod_0112; -.
DR   EnsemblBacteria; ACL55159; ACL55159; Mnod_0112.
DR   KEGG; mno:Mnod_0112; -.
DR   eggNOG; ENOG4105C8K; Bacteria.
DR   eggNOG; COG0216; LUCA.
DR   HOGENOM; HOG000074815; -.
DR   KO; K02835; -.
DR   OMA; WKVEIVS; -.
DR   OrthoDB; POG091H021P; -.
DR   Proteomes; UP000008207; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016149; F:translation release factor activity, codon specific; IEA:InterPro.
DR   HAMAP; MF_00093; Rel_fac_1; 1.
DR   InterPro; IPR005139; PCRF.
DR   InterPro; IPR000352; Pep_chain_release_fac_I_II.
DR   InterPro; IPR004373; PrfA.
DR   Pfam; PF03462; PCRF; 1.
DR   Pfam; PF00472; RF-1; 1.
DR   SMART; SM00937; PCRF; 1.
DR   TIGRFAMs; TIGR00019; prfA; 1.
DR   PROSITE; PS00745; RF_PROK_I; 1.
PE   3: Inferred from homology;
DR   PRODOM; B8IUB4.
DR   SWISS-2DPAGE; B8IUB4.
KW   Complete proteome; Cytoplasm; Methylation; Protein biosynthesis;
KW   Reference proteome.
FT   CHAIN         1    359       Peptide chain release factor 1.
FT                                /FTId=PRO_1000193496.
FT   MOD_RES     234    234       N5-methylglutamine. {ECO:0000255|HAMAP-
FT                                Rule:MF_00093}.
SQ   SEQUENCE   359 AA;  39100 MW;  36B66152B934E31C CRC64;
     MIAIPSDRLD AILARHDIVT ATLSAGEADS ESFVQLSREL SDLDDVVAAI RAYRAADAEL
     RGVEAMLEEG DPEMRALAAE EKPEVEAARD AAAKALQILL LPKDSADEKS AILEIRAGTG
     GDEAALFAGD LFRMYARYAD LKGWKVEVVS ESPGTMGGYR EVVAEVKGRG VFARLKFESG
     AHRVQRVPET ETQGRIHTSA ATVAVLPEAE EVDIHVNEAD LKIDTMRAQG AGGQHVNKTE
     SAIRITHMPS GIVVFVQEER SQHKNRARAM AVLRARLYEQ ERSQKDAARA ADRRAQVGSG
     DRSERIRTYN FPQGRVTDHR INLTLYKLEE VLAGTALDEL VDALVTEHQA ALLAAEGLG
//

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