(data stored in ACNUC7421 zone)

SWISSPROT: B8I9P5_METNO

ID   B8I9P5_METNO            Unreviewed;       299 AA.
AC   B8I9P5;
DT   03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   03-MAR-2009, sequence version 1.
DT   08-MAY-2019, entry version 69.
DE   RecName: Full=Sulfur carrier protein FdhD {ECO:0000256|HAMAP-Rule:MF_00187, ECO:0000256|SAAS:SAAS01091386};
GN   Name=fdhD {ECO:0000256|HAMAP-Rule:MF_00187};
GN   OrderedLocusNames=Mnod_0254 {ECO:0000313|EMBL:ACL55298.1};
OS   Methylobacterium nodulans (strain LMG 21967 / CNCM I-2342 / ORS 2060).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Methylobacteriaceae; Methylobacterium.
OX   NCBI_TaxID=460265 {ECO:0000313|EMBL:ACL55298.1, ECO:0000313|Proteomes:UP000008207};
RN   [1] {ECO:0000313|EMBL:ACL55298.1, ECO:0000313|Proteomes:UP000008207}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LMG 21967 / CNCM I-2342 / ORS 2060
RC   {ECO:0000313|Proteomes:UP000008207};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E.,
RA   Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T.,
RA   Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Ivanova N., Marx C.J., Richardson P.;
RT   "Complete sequence of chromosome of Methylobacterium nodulans ORS
RT   2060.";
RL   Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for formate dehydrogenase (FDH) activity. Acts
CC       as a sulfur carrier protein that transfers sulfur from IscS to the
CC       molybdenum cofactor prior to its insertion into FDH.
CC       {ECO:0000256|HAMAP-Rule:MF_00187}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00187,
CC       ECO:0000256|SAAS:SAAS00093831}.
CC   -!- SIMILARITY: Belongs to the FdhD family. {ECO:0000256|HAMAP-
CC       Rule:MF_00187, ECO:0000256|SAAS:SAAS00573239}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|HAMAP-Rule:MF_00187}.
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DR   EMBL; CP001349; ACL55298.1; -; Genomic_DNA.
DR   STRING; 460265.Mnod_0254; -.
DR   EnsemblBacteria; ACL55298; ACL55298; Mnod_0254.
DR   KEGG; mno:Mnod_0254; -.
DR   eggNOG; ENOG4107H9G; Bacteria.
DR   eggNOG; COG1526; LUCA.
DR   HOGENOM; HOG000079468; -.
DR   KO; K02379; -.
DR   OMA; TPGHDVE; -.
DR   Proteomes; UP000008207; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0097163; F:sulfur carrier activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0016783; F:sulfurtransferase activity; IEA:InterPro.
DR   GO; GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00187; FdhD; 1.
DR   InterPro; IPR016193; Cytidine_deaminase-like.
DR   InterPro; IPR003786; FdhD.
DR   PANTHER; PTHR30592; PTHR30592; 1.
DR   Pfam; PF02634; FdhD-NarQ; 1.
DR   PIRSF; PIRSF015626; FdhD; 1.
DR   SUPFAM; SSF53927; SSF53927; 1.
DR   TIGRFAMs; TIGR00129; fdhD_narQ; 1.
PE   3: Inferred from homology;
DR   PRODOM; B8I9P5.
DR   SWISS-2DPAGE; B8I9P5.
KW   Complete proteome {ECO:0000313|Proteomes:UP000008207};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00187,
KW   ECO:0000256|SAAS:SAAS00464188};
KW   Molybdenum cofactor biosynthesis {ECO:0000256|HAMAP-Rule:MF_00187,
KW   ECO:0000256|SAAS:SAAS00512471};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008207}.
FT   ACT_SITE    134    134       Cysteine persulfide intermediate.
FT                                {ECO:0000256|HAMAP-Rule:MF_00187}.
SQ   SEQUENCE   299 AA;  31273 MW;  036F2D1843DAB3BA CRC64;
     MRKTSPSPAS PNGSMPPSSG GEAAADTAIR VPTQVVAYGD PQARADTRPL AVEMPVNVIY
     GSVPYAVMMT TPADLVDFAY GFSLTEGIVR GADEIRGAAV EPGEGGLRLV VDLAPGRLRE
     HLARKRAMSG RTGCGVCGID DLADIPKAET RPDAGVRVTM AAVERALSAL YDLQILNRET
     RAVHAAAWAD LDGRILAVRE DVGRHNALDK LIGALLRAGT DPAQGFLVIT SRCSFEMAEK
     AASFGASVLV AISAPTSLAV ERAKAHGLTL AAIARSDTVT VFTGAERLLL APDHPEETP
//

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