(data stored in ACNUC7421 zone)

SWISSPROT: B8ICG2_METNO

ID   B8ICG2_METNO            Unreviewed;       286 AA.
AC   B8ICG2;
DT   03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   03-MAR-2009, sequence version 1.
DT   07-JUN-2017, entry version 50.
DE   RecName: Full=Purine nucleoside phosphorylase {ECO:0000256|PIRNR:PIRNR000477};
DE            EC=2.4.2.1 {ECO:0000256|PIRNR:PIRNR000477};
DE   AltName: Full=Inosine-guanosine phosphorylase {ECO:0000256|PIRNR:PIRNR000477};
GN   OrderedLocusNames=Mnod_0509 {ECO:0000313|EMBL:ACL55550.1};
OS   Methylobacterium nodulans (strain LMG 21967 / CNCM I-2342 / ORS 2060).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Methylobacteriaceae; Methylobacterium.
OX   NCBI_TaxID=460265 {ECO:0000313|EMBL:ACL55550.1, ECO:0000313|Proteomes:UP000008207};
RN   [1] {ECO:0000313|EMBL:ACL55550.1, ECO:0000313|Proteomes:UP000008207}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LMG 21967 / CNCM I-2342 / ORS 2060
RC   {ECO:0000313|Proteomes:UP000008207};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E.,
RA   Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T.,
RA   Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Ivanova N., Marx C.J., Richardson P.;
RT   "Complete sequence of chromosome of Methylobacterium nodulans ORS
RT   2060.";
RL   Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: The purine nucleoside phosphorylases catalyze the
CC       phosphorolytic breakdown of the N-glycosidic bond in the beta-
CC       (deoxy)ribonucleoside molecules, with the formation of the
CC       corresponding free purine bases and pentose-1-phosphate.
CC       {ECO:0000256|PIRNR:PIRNR000477}.
CC   -!- CATALYTIC ACTIVITY: Purine nucleoside + phosphate = purine +
CC       alpha-D-ribose 1-phosphate. {ECO:0000256|PIRNR:PIRNR000477}.
CC   -!- PATHWAY: Purine metabolism; purine nucleoside salvage.
CC       {ECO:0000256|PIRNR:PIRNR000477}.
CC   -!- SIMILARITY: Belongs to the PNP/MTAP phosphorylase family.
CC       {ECO:0000256|PIRNR:PIRNR000477}.
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DR   EMBL; CP001349; ACL55550.1; -; Genomic_DNA.
DR   RefSeq; WP_015927260.1; NC_011894.1.
DR   ProteinModelPortal; B8ICG2; -.
DR   STRING; 460265.Mnod_0509; -.
DR   EnsemblBacteria; ACL55550; ACL55550; Mnod_0509.
DR   KEGG; mno:Mnod_0509; -.
DR   eggNOG; ENOG4107RHB; Bacteria.
DR   eggNOG; COG0005; LUCA.
DR   HOGENOM; HOG000045183; -.
DR   KO; K03783; -.
DR   OMA; VLISDHI; -.
DR   OrthoDB; POG091H00GC; -.
DR   UniPathway; UPA00606; -.
DR   Proteomes; UP000008207; Chromosome.
DR   GO; GO:0004731; F:purine-nucleoside phosphorylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009116; P:nucleoside metabolic process; IEA:InterPro.
DR   InterPro; IPR000845; Nucleoside_phosphorylase_d.
DR   InterPro; IPR011269; PUNP.
DR   InterPro; IPR011268; Purine_phosphorylase.
DR   PANTHER; PTHR11904; PTHR11904; 1.
DR   Pfam; PF01048; PNP_UDP_1; 1.
DR   PIRSF; PIRSF000477; PurNPase; 1.
DR   SUPFAM; SSF53167; SSF53167; 1.
DR   TIGRFAMs; TIGR01697; PNPH-PUNA-XAPA; 1.
DR   TIGRFAMs; TIGR01698; PUNP; 1.
PE   3: Inferred from homology;
DR   PRODOM; B8ICG2.
DR   SWISS-2DPAGE; B8ICG2.
KW   Complete proteome {ECO:0000313|Proteomes:UP000008207};
KW   Glycosyltransferase {ECO:0000256|PIRNR:PIRNR000477};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008207};
KW   Transferase {ECO:0000256|PIRNR:PIRNR000477}.
FT   DOMAIN       36    274       PNP_UDP_1. {ECO:0000259|Pfam:PF01048}.
SQ   SEQUENCE   286 AA;  28930 MW;  990F2D2FBF3E3BC7 CRC64;
     MSRGADPSAA GAAADPRVGQ AVARLRAGGF GGPFALAVVA GTGLGPLAAR IEAPRILPYA
     EIPHFPVSGV SGHAGQLVAG DLGGRPVLLF QGRAHAYEQG DAAAMRVPLG VLAALGAPPL
     LLTNAAGSLR HEAGPGRLAL ITDHLNLSGL NPLIGEHSEA RFVPMVDAYD PGLRKSLHGA
     AAAADLVLHE GVYAWFLGPS FETPAEIRMA GRLGADLVGM STVPEVILAR FFGLRVAALS
     IVTNYAAGFD GGAPHHAETK RVAAAAAEDV GRLLAVWLAS GGPGEG
//

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