(data stored in ACNUC8465 zone)

SWISSPROT: C1E0Q4_MICCC

ID   C1E0Q4_MICCC            Unreviewed;       235 AA.
AC   C1E0Q4;
DT   26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT   26-MAY-2009, sequence version 1.
DT   08-MAY-2019, entry version 33.
DE   RecName: Full=Proteasome endopeptidase complex {ECO:0000256|PROSITE-ProRule:PRU00808};
DE            EC=3.4.25.1 {ECO:0000256|PROSITE-ProRule:PRU00808};
GN   ORFNames=MICPUN_56599 {ECO:0000313|EMBL:ACO62042.1};
OS   Micromonas commoda (strain RCC299 / NOUM17 / CCMP2709) (Picoplanktonic
OS   green alga).
OC   Eukaryota; Viridiplantae; Chlorophyta; Mamiellophyceae; Mamiellales;
OC   Mamiellaceae; Micromonas.
OX   NCBI_TaxID=296587 {ECO:0000313|EMBL:ACO62042.1, ECO:0000313|Proteomes:UP000002009};
RN   [1] {ECO:0000313|EMBL:ACO62042.1, ECO:0000313|Proteomes:UP000002009}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RCC299 / NOUM17 {ECO:0000313|Proteomes:UP000002009};
RX   PubMed=19359590; DOI=10.1126/science.1167222;
RA   Worden A.Z., Lee J.H., Mock T., Rouze P., Simmons M.P., Aerts A.L.,
RA   Allen A.E., Cuvelier M.L., Derelle E., Everett M.V., Foulon E.,
RA   Grimwood J., Gundlach H., Henrissat B., Napoli C., McDonald S.M.,
RA   Parker M.S., Rombauts S., Salamov A., Von Dassow P., Badger J.H.,
RA   Coutinho P.M., Demir E., Dubchak I., Gentemann C., Eikrem W.,
RA   Gready J.E., John U., Lanier W., Lindquist E.A., Lucas S., Mayer K.F.,
RA   Moreau H., Not F., Otillar R., Panaud O., Pangilinan J., Paulsen I.,
RA   Piegu B., Poliakov A., Robbens S., Schmutz J., Toulza E., Wyss T.,
RA   Zelensky A., Zhou K., Armbrust E.V., Bhattacharya D., Goodenough U.W.,
RA   Van de Peer Y., Grigoriev I.V.;
RT   "Green evolution and dynamic adaptations revealed by genomes of the
RT   marine picoeukaryotes Micromonas.";
RL   Science 324:268-272(2009).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Cleavage of peptide bonds with very broad specificity.;
CC         EC=3.4.25.1; Evidence={ECO:0000256|PROSITE-ProRule:PRU00808};
CC   -!- SIMILARITY: Belongs to the peptidase T1A family.
CC       {ECO:0000256|PROSITE-ProRule:PRU00808}.
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DR   EMBL; CP001324; ACO62042.1; -; Genomic_DNA.
DR   RefSeq; XP_002500784.1; XM_002500738.1.
DR   STRING; 296587.XP_002500784.1; -.
DR   MEROPS; T01.972; -.
DR   GeneID; 8241532; -.
DR   KEGG; mis:MICPUN_56599; -.
DR   HOGENOM; HOG000091085; -.
DR   InParanoid; C1E0Q4; -.
DR   KO; K02726; -.
DR   OMA; MQIEYAL; -.
DR   OrthoDB; 1222564at2759; -.
DR   Proteomes; UP000002009; Chromosome 3.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0051603; P:proteolysis involved in cellular protein catabolic process; IEA:InterPro.
DR   Gene3D; 3.60.20.10; -; 1.
DR   InterPro; IPR029055; Ntn_hydrolases_N.
DR   InterPro; IPR023332; Proteasome_alpha-type.
DR   InterPro; IPR001353; Proteasome_sua/b.
DR   Pfam; PF00227; Proteasome; 1.
DR   SUPFAM; SSF56235; SSF56235; 1.
DR   PROSITE; PS51475; PROTEASOME_ALPHA_2; 1.
PE   3: Inferred from homology;
DR   PRODOM; C1E0Q4.
DR   SWISS-2DPAGE; C1E0Q4.
KW   Complete proteome {ECO:0000313|Proteomes:UP000002009};
KW   Cytoplasm {ECO:0000256|PROSITE-ProRule:PRU00808};
KW   Hydrolase {ECO:0000256|PROSITE-ProRule:PRU00808};
KW   Protease {ECO:0000256|PROSITE-ProRule:PRU00808};
KW   Proteasome {ECO:0000256|PROSITE-ProRule:PRU00808};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002009};
KW   Threonine protease {ECO:0000256|PROSITE-ProRule:PRU00808}.
SQ   SEQUENCE   235 AA;  25866 MW;  B306A9B4437046E8 CRC64;
     MADSRSNYSL TTFNSSGELV QIKHALAAVQ SGATSLGIRA VNGVVLATEK KLPSTLVDET
     TVEKIAQLTP EIGMTYSGMG PDFRVLTKKT RKETQVYYRT YHELVPCSQI VRETASVMQE
     FTQRGGVRPF GVSLLMAGFD SNGPQLYQVD PSGTYFAWKA SAIGKNMVNA KTFLEKRYSE
     DMELEDAIHT AILTLKEGFD GQISAENIEI GIVAEDRKFR VLTSAEVADY LSEVE
//

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