(data stored in ACNUC7421 zone)

SWISSPROT: HRCA_SINFN

ID   HRCA_SINFN              Reviewed;         359 AA.
AC   C3MEJ2;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   16-JUN-2009, sequence version 1.
DT   07-JUN-2017, entry version 52.
DE   RecName: Full=Heat-inducible transcription repressor HrcA {ECO:0000255|HAMAP-Rule:MF_00081};
GN   Name=hrcA {ECO:0000255|HAMAP-Rule:MF_00081};
GN   OrderedLocusNames=NGR_c00110;
OS   Sinorhizobium fredii (strain NBRC 101917 / NGR234).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX   NCBI_TaxID=394;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 101917 / NGR234;
RX   PubMed=19376903; DOI=10.1128/AEM.00515-09;
RA   Schmeisser C., Liesegang H., Krysciak D., Bakkou N., Le Quere A.,
RA   Wollherr A., Heinemeyer I., Morgenstern B., Pommerening-Roeser A.,
RA   Flores M., Palacios R., Brenner S., Gottschalk G., Schmitz R.A.,
RA   Broughton W.J., Perret X., Strittmatter A.W., Streit W.R.;
RT   "Rhizobium sp. strain NGR234 possesses a remarkable number of
RT   secretion systems.";
RL   Appl. Environ. Microbiol. 75:4035-4045(2009).
CC   -!- FUNCTION: Negative regulator of class I heat shock genes (grpE-
CC       dnaK-dnaJ and groELS operons). Prevents heat-shock induction of
CC       these operons. {ECO:0000255|HAMAP-Rule:MF_00081}.
CC   -!- SIMILARITY: Belongs to the HrcA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00081}.
DR   EMBL; CP001389; ACP23815.1; -; Genomic_DNA.
DR   RefSeq; WP_012706600.1; NC_012587.1.
DR   RefSeq; YP_002824568.1; NC_012587.1.
DR   SMR; C3MEJ2; -.
DR   STRING; 394.NGR_c00110; -.
DR   EnsemblBacteria; ACP23815; ACP23815; NGR_c00110.
DR   GeneID; 7790590; -.
DR   KEGG; rhi:NGR_c00110; -.
DR   PATRIC; fig|394.7.peg.2801; -.
DR   eggNOG; ENOG4105CI8; Bacteria.
DR   eggNOG; COG1420; LUCA.
DR   HOGENOM; HOG000058933; -.
DR   KO; K03705; -.
DR   OMA; GPKRMDY; -.
DR   OrthoDB; POG091H01WV; -.
DR   Proteomes; UP000001054; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 3.30.450.40; -; 1.
DR   HAMAP; MF_00081; HrcA; 1.
DR   InterPro; IPR029016; GAF_dom-like.
DR   InterPro; IPR002571; HrcA.
DR   InterPro; IPR021153; HrcA_C.
DR   InterPro; IPR011991; WHTH_DNA-bd_dom.
DR   PANTHER; PTHR34824:SF2; PTHR34824:SF2; 1.
DR   Pfam; PF01628; HrcA; 1.
DR   PIRSF; PIRSF005485; HrcA; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF55781; SSF55781; 1.
DR   TIGRFAMs; TIGR00331; hrcA; 1.
PE   3: Inferred from homology;
DR   PRODOM; C3MEJ2.
DR   SWISS-2DPAGE; C3MEJ2.
KW   Complete proteome; Reference proteome; Repressor; Stress response;
KW   Transcription; Transcription regulation.
FT   CHAIN         1    359       Heat-inducible transcription repressor
FT                                HrcA.
FT                                /FTId=PRO_1000118312.
SQ   SEQUENCE   359 AA;  39413 MW;  6296EE27CE3B3D19 CRC64;
     MVLRNPEKKG IASTLDERSG EIFRRIVETY LESGEPLGSR NLSRLLPMSL SPASVRNVMS
     DLEDLGLIYS PHVSAGRLPT QTGLRFFVDA FMQVGNLSAE ERTSIERQVR RADRDQPIDS
     LLAEASQMLS GMSRGAGLVI TTKSDPVLKH VEFIRLAPTK ALAVLVGDHD QVENRIIELP
     AGITSAQLTE AANFVNAHLA GQTIPELRSQ LEKVKETVRG ELDALSQDLV ERGLAIWSGS
     EGDEKPARLI VRGRANLLEG LEGTEDIERL RMLFDDLEKK DSLIELLDLA ESGPGVRIFI
     GSENKLFSLS GSSLIVAPYR DSDDRIVGAV GVIGPTRLNY SRIVPMVDYT AQLMSRLSR
//

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