(data stored in ACNUC7421 zone)

SWISSPROT: YIDC_SINFN

ID   YIDC_SINFN              Reviewed;         592 AA.
AC   C3MF49;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   16-JUN-2009, sequence version 1.
DT   07-JUN-2017, entry version 43.
DE   RecName: Full=Membrane protein insertase YidC {ECO:0000255|HAMAP-Rule:MF_01810};
DE   AltName: Full=Foldase YidC {ECO:0000255|HAMAP-Rule:MF_01810};
DE   AltName: Full=Membrane integrase YidC {ECO:0000255|HAMAP-Rule:MF_01810};
DE   AltName: Full=Membrane protein YidC {ECO:0000255|HAMAP-Rule:MF_01810};
GN   Name=yidC {ECO:0000255|HAMAP-Rule:MF_01810};
GN   OrderedLocusNames=NGR_c00820;
OS   Sinorhizobium fredii (strain NBRC 101917 / NGR234).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX   NCBI_TaxID=394;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 101917 / NGR234;
RX   PubMed=19376903; DOI=10.1128/AEM.00515-09;
RA   Schmeisser C., Liesegang H., Krysciak D., Bakkou N., Le Quere A.,
RA   Wollherr A., Heinemeyer I., Morgenstern B., Pommerening-Roeser A.,
RA   Flores M., Palacios R., Brenner S., Gottschalk G., Schmitz R.A.,
RA   Broughton W.J., Perret X., Strittmatter A.W., Streit W.R.;
RT   "Rhizobium sp. strain NGR234 possesses a remarkable number of
RT   secretion systems.";
RL   Appl. Environ. Microbiol. 75:4035-4045(2009).
CC   -!- FUNCTION: Required for the insertion and/or proper folding and/or
CC       complex formation of integral membrane proteins into the membrane.
CC       Involved in integration of membrane proteins that insert both
CC       dependently and independently of the Sec translocase complex, as
CC       well as at least some lipoproteins. Aids folding of multispanning
CC       membrane proteins. {ECO:0000255|HAMAP-Rule:MF_01810}.
CC   -!- SUBUNIT: Interacts with the Sec translocase complex via SecD.
CC       Specifically interacts with transmembrane segments of nascent
CC       integral membrane proteins during membrane integration.
CC       {ECO:0000255|HAMAP-Rule:MF_01810}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01810}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01810}.
CC   -!- SIMILARITY: Belongs to the OXA1/ALB3/YidC family. Type 1
CC       subfamily. {ECO:0000255|HAMAP-Rule:MF_01810}.
DR   EMBL; CP001389; ACP23886.1; -; Genomic_DNA.
DR   RefSeq; WP_012706671.1; NC_012587.1.
DR   RefSeq; YP_002824639.1; NC_012587.1.
DR   STRING; 394.NGR_c00820; -.
DR   EnsemblBacteria; ACP23886; ACP23886; NGR_c00820.
DR   GeneID; 7790661; -.
DR   KEGG; rhi:NGR_c00820; -.
DR   PATRIC; fig|394.7.peg.2875; -.
DR   eggNOG; ENOG4105DHW; Bacteria.
DR   eggNOG; COG0706; LUCA.
DR   HOGENOM; HOG000101821; -.
DR   KO; K03217; -.
DR   OMA; INPVAGC; -.
DR   OrthoDB; POG091H00BE; -.
DR   Proteomes; UP000001054; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0051205; P:protein insertion into membrane; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   HAMAP; MF_01810; YidC_type1; 1.
DR   InterPro; IPR019998; Membr_insert_YidC.
DR   InterPro; IPR028055; Membr_insert_YidC/Oxa1_C.
DR   InterPro; IPR028053; Membr_insert_YidC_N.
DR   InterPro; IPR001708; Membrane_insert_OXA1/ALB3/YidC.
DR   PANTHER; PTHR12428; PTHR12428; 1.
DR   Pfam; PF02096; 60KD_IMP; 1.
DR   Pfam; PF14849; YidC_periplas; 1.
DR   PRINTS; PR00701; 60KDINNERMP.
DR   PRINTS; PR01900; YIDCPROTEIN.
DR   TIGRFAMs; TIGR03593; yidC_nterm; 1.
DR   TIGRFAMs; TIGR03592; yidC_oxa1_cterm; 1.
PE   3: Inferred from homology;
DR   PRODOM; C3MF49.
DR   SWISS-2DPAGE; C3MF49.
KW   Cell inner membrane; Cell membrane; Chaperone; Complete proteome;
KW   Membrane; Protein transport; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN         1    592       Membrane protein insertase YidC.
FT                                /FTId=PRO_1000187694.
FT   TRANSMEM      7     27       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01810}.
FT   TRANSMEM    367    387       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01810}.
FT   TRANSMEM    441    461       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01810}.
FT   TRANSMEM    486    506       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01810}.
FT   TRANSMEM    530    550       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01810}.
SQ   SEQUENCE   592 AA;  66033 MW;  27EF135DF9A27F9D CRC64;
     MMENNRNYFV AIALSVLILV AWQYFYVNPR MDKDRIAAEK AQQTQQVQPQ QGGQQPAPGQ
     ALPGGAVPGE SRDQAVAKSA RVAIDTPALS GSINLTGARF DDLKLKGYHE TVDPKSPVIT
     LFSPAETADG YFTEIGYIGN DASGSVPGPQ TVWTLSGGEK LTPATPVTLT YTNDKGITFA
     RTISIDENYM FQVVDSIKND GSAPVSLSSY GRVTRFNKPT TPSIYVLHEG FIGVAGGSLQ
     EVGYSKIEEN LPVEPGKTTG GWHGITDKYW AAAIVPPQET PFDIRFSHFT DGRPRFQSDY
     KGDAVTVAPG QSAEVKNLVF AGAKEVQVVD TYTTAYAIPK FEKLIDWGWF WFITQPMFKM
     MDFFFRLFGN FGVAILVTTI VVKLIFFPLA NKQYASMANM KKVQPKMEEL KKKFGDDRMG
     LQQAMMQLYK DEKINPLAGC WPILIQIPVF FALYKVIYIT IEMRHAPFFG WIRDLSAPDP
     TTIVNLFGLL PFDGPAFLHL GIWPIIMGVT MFLQMRMNPT PPDPTQAMLF TWMPLVFTFM
     LASFPAGLVI YWAWNNTLSI TQQSIIMKRQ GVKIELFDNL KGLFTKRPKP AE
//

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