(data stored in ACNUC7421 zone)

SWISSPROT: C3MFR7_SINFN

ID   C3MFR7_SINFN            Unreviewed;       402 AA.
AC   C3MFR7;
DT   16-JUN-2009, integrated into UniProtKB/TrEMBL.
DT   16-JUN-2009, sequence version 1.
DT   30-AUG-2017, entry version 55.
DE   SubName: Full=Acetyl-CoA acetyltransferase {ECO:0000313|EMBL:ACP23968.1};
DE            EC=2.3.1.16 {ECO:0000313|EMBL:ACP23968.1};
GN   Name=fadA {ECO:0000313|EMBL:ACP23968.1};
GN   OrderedLocusNames=NGR_c01680 {ECO:0000313|EMBL:ACP23968.1};
OS   Sinorhizobium fredii (strain NBRC 101917 / NGR234).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX   NCBI_TaxID=394 {ECO:0000313|EMBL:ACP23968.1, ECO:0000313|Proteomes:UP000001054};
RN   [1] {ECO:0000313|EMBL:ACP23968.1, ECO:0000313|Proteomes:UP000001054}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 101917 / NGR234 {ECO:0000313|Proteomes:UP000001054};
RX   PubMed=19376903; DOI=10.1128/AEM.00515-09;
RA   Schmeisser C., Liesegang H., Krysciak D., Bakkou N., Le Quere A.,
RA   Wollherr A., Heinemeyer I., Morgenstern B., Pommerening-Roeser A.,
RA   Flores M., Palacios R., Brenner S., Gottschalk G., Schmitz R.A.,
RA   Broughton W.J., Perret X., Strittmatter A.W., Streit W.R.;
RT   "Rhizobium sp. strain NGR234 possesses a remarkable number of
RT   secretion systems.";
RL   Appl. Environ. Microbiol. 75:4035-4045(2009).
CC   -!- SIMILARITY: Belongs to the thiolase family.
CC       {ECO:0000256|RuleBase:RU003557}.
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DR   EMBL; CP001389; ACP23968.1; -; Genomic_DNA.
DR   RefSeq; WP_012706753.1; NC_012587.1.
DR   RefSeq; YP_002824721.1; NC_012587.1.
DR   STRING; 394.NGR_c01680; -.
DR   EnsemblBacteria; ACP23968; ACP23968; NGR_c01680.
DR   GeneID; 7790746; -.
DR   KEGG; rhi:NGR_c01680; -.
DR   PATRIC; fig|394.7.peg.2963; -.
DR   eggNOG; ENOG4105CHU; Bacteria.
DR   eggNOG; COG0183; LUCA.
DR   HOGENOM; HOG000012239; -.
DR   KO; K00626; -.
DR   OMA; TDMQSLA; -.
DR   OrthoDB; POG091H09ZQ; -.
DR   Proteomes; UP000001054; Chromosome.
DR   GO; GO:0003988; F:acetyl-CoA C-acyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008152; P:metabolic process; IEA:InterPro.
DR   CDD; cd00751; thiolase; 1.
DR   Gene3D; 3.40.47.10; -; 2.
DR   InterPro; IPR002155; Thiolase.
DR   InterPro; IPR016039; Thiolase-like.
DR   InterPro; IPR020615; Thiolase_acyl_enz_int_AS.
DR   InterPro; IPR020610; Thiolase_AS.
DR   InterPro; IPR020617; Thiolase_C.
DR   InterPro; IPR020613; Thiolase_CS.
DR   InterPro; IPR020616; Thiolase_N.
DR   Pfam; PF02803; Thiolase_C; 1.
DR   Pfam; PF00108; Thiolase_N; 1.
DR   PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR   SUPFAM; SSF53901; SSF53901; 2.
DR   TIGRFAMs; TIGR01930; AcCoA-C-Actrans; 1.
DR   PROSITE; PS00098; THIOLASE_1; 1.
DR   PROSITE; PS00737; THIOLASE_2; 1.
DR   PROSITE; PS00099; THIOLASE_3; 1.
PE   3: Inferred from homology;
DR   PRODOM; C3MFR7.
DR   SWISS-2DPAGE; C3MFR7.
KW   Acyltransferase {ECO:0000256|RuleBase:RU003557,
KW   ECO:0000313|EMBL:ACP23968.1};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001054};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001054};
KW   Transferase {ECO:0000256|RuleBase:RU003557,
KW   ECO:0000313|EMBL:ACP23968.1}.
FT   DOMAIN        4    229       Thiolase_N. {ECO:0000259|Pfam:PF00108}.
FT   DOMAIN      279    401       Thiolase_C. {ECO:0000259|Pfam:PF02803}.
FT   ACT_SITE     91     91       Acyl-thioester intermediate.
FT                                {ECO:0000256|PIRSR:PIRSR000429-1}.
FT   ACT_SITE    358    358       Proton acceptor. {ECO:0000256|PIRSR:
FT                                PIRSR000429-1}.
FT   ACT_SITE    388    388       Proton acceptor. {ECO:0000256|PIRSR:
FT                                PIRSR000429-1}.
SQ   SEQUENCE   402 AA;  42564 MW;  FDAECA5F093A92E4 CRC64;
     MTKVFVYDHV RTPRGRGKKD GSLHEVPSVR LAAKVLEAVR DRNGLDTATV DDIVMGCVDP
     VMDAGSVIPK AAAFEAGYST RAPGMQISRF CASGLDAVNF GAAKIAQGAD DIVIAGGVES
     MSRVGLGMSG GSWFMDPSVS LPAYFMPQGV SADLIATKYG FSRDDVDAYA VESQKRAAHA
     WEKGYFENSV VPVKDQNGLT ILDRDEHMRP GTDMQALASL NPSFQMPGEM GGFEAVAIQA
     HPEIERINYV HHAGNSSGIV DGAAAVLLGS KAGGEAMGLK PRARIRAFAN IGSDPALMLT
     GPVDVTEKLL KRADMKLSDI DLFELNEAFA AVVLRFMQAF DIPHDQINVN GGAIAMGHPL
     GATGAMILGT VLDELERRDL NTALVTLCIG AGMGTATIIE RV
//

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