(data stored in ACNUC7421 zone)

SWISSPROT: C3MFX5_SINFN

ID   C3MFX5_SINFN            Unreviewed;        87 AA.
AC   C3MFX5;
DT   16-JUN-2009, integrated into UniProtKB/TrEMBL.
DT   16-JUN-2009, sequence version 1.
DT   07-JUN-2017, entry version 61.
DE   RecName: Full=Translation initiation factor IF-1 {ECO:0000256|HAMAP-Rule:MF_00075};
GN   Name=infA {ECO:0000256|HAMAP-Rule:MF_00075};
GN   OrderedLocusNames=NGR_c02270 {ECO:0000313|EMBL:ACP24026.1};
OS   Sinorhizobium fredii (strain NBRC 101917 / NGR234).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX   NCBI_TaxID=394 {ECO:0000313|EMBL:ACP24026.1, ECO:0000313|Proteomes:UP000001054};
RN   [1] {ECO:0000313|EMBL:ACP24026.1, ECO:0000313|Proteomes:UP000001054}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 101917 / NGR234 {ECO:0000313|Proteomes:UP000001054};
RX   PubMed=19376903; DOI=10.1128/AEM.00515-09;
RA   Schmeisser C., Liesegang H., Krysciak D., Bakkou N., Le Quere A.,
RA   Wollherr A., Heinemeyer I., Morgenstern B., Pommerening-Roeser A.,
RA   Flores M., Palacios R., Brenner S., Gottschalk G., Schmitz R.A.,
RA   Broughton W.J., Perret X., Strittmatter A.W., Streit W.R.;
RT   "Rhizobium sp. strain NGR234 possesses a remarkable number of
RT   secretion systems.";
RL   Appl. Environ. Microbiol. 75:4035-4045(2009).
CC   -!- FUNCTION: One of the essential components for the initiation of
CC       protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the
CC       30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently
CC       binds. Helps modulate mRNA selection, yielding the 30S pre-
CC       initiation complex (PIC). Upon addition of the 50S ribosomal
CC       subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S
CC       translation initation complex. {ECO:0000256|HAMAP-Rule:MF_00075,
CC       ECO:0000256|SAAS:SAAS00571772}.
CC   -!- SUBUNIT: Component of the 30S ribosomal translation pre-initiation
CC       complex which assembles on the 30S ribosome in the order IF-2 and
CC       IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can
CC       occur at any time during PIC assembly. {ECO:0000256|HAMAP-
CC       Rule:MF_00075, ECO:0000256|SAAS:SAAS00385842}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00075}.
CC   -!- SIMILARITY: Belongs to the IF-1 family. {ECO:0000256|HAMAP-
CC       Rule:MF_00075, ECO:0000256|SAAS:SAAS00571750}.
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DR   EMBL; CP001389; ACP24026.1; -; Genomic_DNA.
DR   RefSeq; WP_012706811.1; NC_012587.1.
DR   RefSeq; YP_002824779.1; NC_012587.1.
DR   STRING; 394.NGR_c02270; -.
DR   EnsemblBacteria; ACP24026; ACP24026; NGR_c02270.
DR   GeneID; 7790805; -.
DR   KEGG; rhi:NGR_c02270; -.
DR   PATRIC; fig|394.7.peg.3027; -.
DR   eggNOG; ENOG4105K9U; Bacteria.
DR   eggNOG; COG0361; LUCA.
DR   HOGENOM; HOG000221323; -.
DR   KO; K02518; -.
DR   OMA; AHVSGKM; -.
DR   OrthoDB; POG091H019C; -.
DR   Proteomes; UP000001054; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0043022; F:ribosome binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-HAMAP.
DR   CDD; cd04451; S1_IF1; 1.
DR   HAMAP; MF_00075; IF_1; 1.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR006196; RNA-binding_domain_S1_IF1.
DR   InterPro; IPR004368; TIF_IF1.
DR   Pfam; PF01176; eIF-1a; 1.
DR   SUPFAM; SSF50249; SSF50249; 1.
DR   TIGRFAMs; TIGR00008; infA; 1.
DR   PROSITE; PS50832; S1_IF1_TYPE; 1.
PE   3: Inferred from homology;
DR   PRODOM; C3MFX5.
DR   SWISS-2DPAGE; C3MFX5.
KW   Complete proteome {ECO:0000313|Proteomes:UP000001054};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00075};
KW   Initiation factor {ECO:0000256|HAMAP-Rule:MF_00075,
KW   ECO:0000256|PROSITE-ProRule:PRU00181, ECO:0000256|SAAS:SAAS00090884,
KW   ECO:0000313|EMBL:ACP24026.1};
KW   Protein biosynthesis {ECO:0000256|HAMAP-Rule:MF_00075,
KW   ECO:0000256|PROSITE-ProRule:PRU00181, ECO:0000256|SAAS:SAAS00090890};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001054};
KW   RNA-binding {ECO:0000256|HAMAP-Rule:MF_00075,
KW   ECO:0000256|SAAS:SAAS00571736};
KW   rRNA-binding {ECO:0000256|HAMAP-Rule:MF_00075,
KW   ECO:0000256|SAAS:SAAS00571793}.
FT   DOMAIN       12     87       S1-like. {ECO:0000259|PROSITE:PS50832}.
SQ   SEQUENCE   87 AA;  9958 MW;  E93130E260DC630B CRC64;
     MRGASAVEHE KAQSFMAKEE VLEFPGVVTE LLPNATFRVK LENDHEIIAH TAGRMRKNRI
     RVLAGDKVLV EMTPYDLTKG RITYRFK
//

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