(data stored in ACNUC7421 zone)

SWISSPROT: YACG_SINFN

ID   YACG_SINFN              Reviewed;          69 AA.
AC   C3MFX7;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   16-JUN-2009, sequence version 1.
DT   07-JUN-2017, entry version 53.
DE   RecName: Full=DNA gyrase inhibitor YacG {ECO:0000255|HAMAP-Rule:MF_00649};
GN   Name=yacG {ECO:0000255|HAMAP-Rule:MF_00649};
GN   OrderedLocusNames=NGR_c02290;
OS   Sinorhizobium fredii (strain NBRC 101917 / NGR234).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX   NCBI_TaxID=394;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 101917 / NGR234;
RX   PubMed=19376903; DOI=10.1128/AEM.00515-09;
RA   Schmeisser C., Liesegang H., Krysciak D., Bakkou N., Le Quere A.,
RA   Wollherr A., Heinemeyer I., Morgenstern B., Pommerening-Roeser A.,
RA   Flores M., Palacios R., Brenner S., Gottschalk G., Schmitz R.A.,
RA   Broughton W.J., Perret X., Strittmatter A.W., Streit W.R.;
RT   "Rhizobium sp. strain NGR234 possesses a remarkable number of
RT   secretion systems.";
RL   Appl. Environ. Microbiol. 75:4035-4045(2009).
CC   -!- FUNCTION: Inhibits all the catalytic activities of DNA gyrase by
CC       preventing its interaction with DNA. Acts by binding directly to
CC       the C-terminal domain of GyrB, which probably disrupts DNA binding
CC       by the gyrase. {ECO:0000255|HAMAP-Rule:MF_00649}.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00649};
CC       Note=Binds 1 zinc ion. {ECO:0000255|HAMAP-Rule:MF_00649};
CC   -!- SUBUNIT: Interacts with GyrB. {ECO:0000255|HAMAP-Rule:MF_00649}.
CC   -!- SIMILARITY: Belongs to the DNA gyrase inhibitor YacG family.
CC       {ECO:0000255|HAMAP-Rule:MF_00649}.
DR   EMBL; CP001389; ACP24028.1; -; Genomic_DNA.
DR   RefSeq; WP_012706813.1; NC_012587.1.
DR   RefSeq; YP_002824781.1; NC_012587.1.
DR   SMR; C3MFX7; -.
DR   STRING; 394.NGR_c02290; -.
DR   EnsemblBacteria; ACP24028; ACP24028; NGR_c02290.
DR   GeneID; 7790807; -.
DR   KEGG; rhi:NGR_c02290; -.
DR   PATRIC; fig|394.7.peg.3029; -.
DR   eggNOG; ENOG41086Q3; Bacteria.
DR   eggNOG; COG3024; LUCA.
DR   HOGENOM; HOG000255917; -.
DR   KO; K09862; -.
DR   OMA; CSNRCRE; -.
DR   OrthoDB; POG091H04DF; -.
DR   Proteomes; UP000001054; Chromosome.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   Gene3D; 3.30.50.10; -; 1.
DR   HAMAP; MF_00649; DNA_gyrase_inhibitor_YacG; 1.
DR   InterPro; IPR005584; DNA_gyrase_inhibitor_YacG.
DR   InterPro; IPR013088; Znf_NHR/GATA.
DR   Pfam; PF03884; YacG; 1.
PE   3: Inferred from homology;
DR   PRODOM; C3MFX7.
DR   SWISS-2DPAGE; C3MFX7.
KW   Complete proteome; Metal-binding; Reference proteome; Zinc.
FT   CHAIN         1     69       DNA gyrase inhibitor YacG.
FT                                /FTId=PRO_1000200413.
FT   METAL        21     21       Zinc. {ECO:0000255|HAMAP-Rule:MF_00649}.
FT   METAL        24     24       Zinc. {ECO:0000255|HAMAP-Rule:MF_00649}.
FT   METAL        36     36       Zinc. {ECO:0000255|HAMAP-Rule:MF_00649}.
FT   METAL        40     40       Zinc. {ECO:0000255|HAMAP-Rule:MF_00649}.
SQ   SEQUENCE   69 AA;  7824 MW;  DC7F213B4DD4435A CRC64;
     MSGEGKKHGS NVEPLRPTRP CPECGRPSVR ERYPFCSERC RNVDLNRWLS GSYAIPVADD
     ESKADDEDR
//

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