(data stored in ACNUC7421 zone)

SWISSPROT: CBID_SULIK

ID   CBID_SULIK              Reviewed;         349 AA.
AC   C4KJM9;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   07-JUL-2009, sequence version 1.
DT   07-JUN-2017, entry version 40.
DE   RecName: Full=Cobalt-precorrin-5B C(1)-methyltransferase {ECO:0000255|HAMAP-Rule:MF_00787};
DE            EC=2.1.1.195 {ECO:0000255|HAMAP-Rule:MF_00787};
DE   AltName: Full=Cobalt-precorrin-6A synthase {ECO:0000255|HAMAP-Rule:MF_00787};
GN   Name=cbiD {ECO:0000255|HAMAP-Rule:MF_00787};
GN   OrderedLocusNames=M164_0113;
OS   Sulfolobus islandicus (strain M.16.4 / Kamchatka #3).
OC   Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC   Sulfolobus.
OX   NCBI_TaxID=426118;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=M.16.4 / Kamchatka #3;
RX   PubMed=19435847; DOI=10.1073/pnas.0808945106;
RA   Reno M.L., Held N.L., Fields C.J., Burke P.V., Whitaker R.J.;
RT   "Biogeography of the Sulfolobus islandicus pan-genome.";
RL   Proc. Natl. Acad. Sci. U.S.A. 106:8605-8610(2009).
CC   -!- FUNCTION: Catalyzes the methylation of C-1 in cobalt-precorrin-5B
CC       to form cobalt-precorrin-6A. {ECO:0000255|HAMAP-Rule:MF_00787}.
CC   -!- CATALYTIC ACTIVITY: Cobalt-precorrin-5B + S-adenosyl-L-methionine
CC       = cobalt-precorrin-6A + S-adenosyl-L-homocysteine.
CC       {ECO:0000255|HAMAP-Rule:MF_00787}.
CC   -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis;
CC       cob(II)yrinate a,c-diamide from sirohydrochlorin (anaerobic
CC       route): step 6/10. {ECO:0000255|HAMAP-Rule:MF_00787}.
CC   -!- SIMILARITY: Belongs to the CbiD family. {ECO:0000255|HAMAP-
CC       Rule:MF_00787}.
DR   EMBL; CP001402; ACR40749.1; -; Genomic_DNA.
DR   RefSeq; WP_012710290.1; NC_012726.1.
DR   SMR; C4KJM9; -.
DR   EnsemblBacteria; ACR40749; ACR40749; M164_0113.
DR   GeneID; 7813722; -.
DR   KEGG; sid:M164_0113; -.
DR   HOGENOM; HOG000009126; -.
DR   KO; K02188; -.
DR   OMA; GGIFHTH; -.
DR   OrthoDB; POG093Z05FA; -.
DR   BioCyc; SISL426118:GI01-113-MONOMER; -.
DR   UniPathway; UPA00148; UER00227.
DR   Proteomes; UP000001479; Chromosome.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR   HAMAP; MF_00787; CbiD; 1.
DR   InterPro; IPR002748; CbiD.
DR   PANTHER; PTHR35863; PTHR35863; 1.
DR   Pfam; PF01888; CbiD; 1.
DR   PIRSF; PIRSF026782; CbiD; 1.
DR   SUPFAM; SSF111342; SSF111342; 1.
DR   TIGRFAMs; TIGR00312; cbiD; 1.
PE   3: Inferred from homology;
DR   PRODOM; C4KJM9.
DR   SWISS-2DPAGE; C4KJM9.
KW   Cobalamin biosynthesis; Complete proteome; Methyltransferase;
KW   S-adenosyl-L-methionine; Transferase.
FT   CHAIN         1    349       Cobalt-precorrin-5B C(1)-
FT                                methyltransferase.
FT                                /FTId=PRO_1000212941.
SQ   SEQUENCE   349 AA;  37432 MW;  BC5895F96867E63C CRC64;
     MIINSLKRFG ITTGAAASAA AKAAVIGLLN REKRNTVVIP TPIGLRLEIP VEKVEIDSGI
     ACAEVKKFSG DNPDILDGLA IRCCAKLNES NEIVIVGGKG VGKVTRSGLK ATMGETAISP
     TVRDMVINAI REVTDKGIQI TIEVPNGDII AENTLNKMVG IVGGISILGT TGIETPVSDD
     DYLEHIKCEL NVIRQSYDFV VIAPGNSAAK YASKLFDSNS IIKVGDRIGD SIKLASSVFR
     KVILAGLPAK LLKVYAGIFN THFSQGDARL ESLTHASVLA GLPYDVLTKI TNALSVEEAF
     TYMTKEQRRK VMKIVAEKIL SRIKSFNGDI NFCVIIFDYD GESLSRVGC
//

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